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Low-dose Positron Emission Tomography (PET) reduces radiation exposure but suffers from severe noise and quantitative degradation. Diffusion-based denoising models achieve strong final reconstructions, yet their reverse trajectories are…

Positron emission tomography (PET) is a widely recognized technique for diagnosing neurodegenerative diseases, offering critical functional insights. However, its high costs and radiation exposure hinder its widespread use. In contrast,…

计算机视觉与模式识别 · 计算机科学 2026-03-20 Yitong Li , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger

Dynamic positron emission tomography (PET) and kinetic modeling are pivotal in advancing tracer development research in small animal studies. Accurate kinetic modeling requires precise input function estimation, traditionally achieved via…

Fully Field Programmable Gate Array (FPGA)based digitizer for high-resolution time and energy measurement is an attractive low cost solution for the readout electronics in positron emission computed tomography (PET)detector. In recent…

仪器与探测器 · 物理学 2022-01-07 Cong Ma , Wubin Wang , Xiaokun Zhao , Li Yu , Guocheng Wu

Dynamic positron emission tomography (PET) with [$^{18}$F]FDG enables non-invasive quantification of glucose metabolism through kinetic analysis, often modelled by the two-tissue compartment model (TCKM). However, voxel-wise kinetic…

图像与视频处理 · 电气工程与系统科学 2025-04-25 Kartikay Tehlan , Thomas Wendler

Positron emission tomography (PET) is widely utilized for cancer detection due to its ability to visualize functional and biological processes in vivo. PET images are usually reconstructed from histogrammed raw data (sinograms) using…

图像与视频处理 · 电气工程与系统科学 2024-11-26 Yiran Sun , Osama Mawlawi

To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One…

图像与视频处理 · 电气工程与系统科学 2023-08-22 Zeyu Han , Yuhan Wang , Luping Zhou , Peng Wang , Binyu Yan , Jiliu Zhou , Yan Wang , Dinggang Shen

Purpose: To test the feasibility of using deep learning for optical coherence tomography angiography (OCTA) detection of diabetic retinopathy (DR). Methods: A deep learning convolutional neural network (CNN) architecture VGG16 was employed…

定量方法 · 定量生物学 2021-12-16 David Le , Minhaj Alam , Cham Yao , Jennifer I. Lim , R. V. P. Chan , Devrim Toslak , Xincheng Yao

Parkinson's Disease (PD) is a neurodegenerative disease that currently does not have a cure. In order to facilitate disease management and reduce the speed of symptom progression, early diagnosis is essential. The current clinical,…

图像与视频处理 · 电气工程与系统科学 2019-09-11 Justin Quan , Lin Xu , Rene Xu , Tyrael Tong , Jean Su

Small animal Positron Emission Tomography (PET) is dedicated to small animal imaging. Animals used in experiments, such as rats and monkeys, are often much smaller than human bodies, which requires higher position and energy precision of…

信号处理 · 电气工程与系统科学 2018-06-26 Jiaming Lu , Lei Zhao , Peipei Deng , Bowen Li , Kairen Chen , Shubin Liu , Qi An

Positron emission tomography (PET) imaging is widely used in a number of clinical applications, including cancer and Alzheimer's disease (AD) diagnosis, monitoring of disease development, and treatment effect evaluation. Statistical…

组织与器官 · 定量生物学 2025-11-07 Akhil Ambekar , Robert Zielinski , Ani Eloyan

Tumor segmentation in medical imaging is crucial and relies on precise delineation. Fluorodeoxyglucose Positron-Emission Tomography (FDG-PET) is widely used in clinical practice to detect metabolically active tumors. However, FDG-PET scans…

图像与视频处理 · 电气工程与系统科学 2023-10-05 Matthias Hadlich , Zdravko Marinov , Rainer Stiefelhagen

Low-dose Positron Emission Tomography (PET) imaging presents a significant challenge due to increased noise and reduced image quality, which can compromise its diagnostic accuracy and clinical utility. Denoising diffusion probabilistic…

图像与视频处理 · 电气工程与系统科学 2025-03-03 Boxiao Yu , Savas Ozdemir , Jiong Wu , Yizhou Chen , Ruogu Fang , Kuangyu Shi , Kuang Gong

A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…

The great success of Deep Neural Networks (DNNs) has inspired the algorithmic development of DNN-based Fixed-Point (DNN-FP) for computer vision tasks. DNN-FP methods, trained by Back-Propagation Through Time or computing the inaccurate…

计算机视觉与模式识别 · 计算机科学 2023-01-31 Peng Qiao , Sidun Liu , Tao Sun , Ke Yang , Yong Dou

Dynamic 2-[18F] fluoro-2-deoxy-D-glucose positron emission tomography (dFDG-PET) for human brain imaging has considerable clinical potential, yet its utilization remains limited. A key challenge in the quantitative analysis of dFDG-PET is…

Background and Objective. Research in the cross-modal medical image translation domain has been very productive over the past few years in tackling the scarce availability of large curated multimodality datasets with the promising…

图像与视频处理 · 电气工程与系统科学 2025-05-13 Daria Zotova , Nicolas Pinon , Robin Trombetta , Romain Bouet , Julien Jung , Carole Lartizien

Positron Emission Tomography (PET) and Computed Tomography (CT) are essential for diagnosing, staging, and monitoring various diseases, particularly cancer. Despite their importance, the use of PET/CT systems is limited by the necessity for…

图像与视频处理 · 电气工程与系统科学 2024-10-30 Dac Thai Nguyen , Trung Thanh Nguyen , Huu Tien Nguyen , Thanh Trung Nguyen , Huy Hieu Pham , Thanh Hung Nguyen , Thao Nguyen Truong , Phi Le Nguyen

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

医学物理 · 物理学 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

医学物理 · 物理学 2021-01-27 Karl Spuhler , Mario Serrano-Sosa , Renee Cattell , Christine DeLorenzo , Chuan Huang