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Large Language Models (LLMs) have shown superior performance in various applications and fields. To achieve better performance on specialized domains such as law and advertisement, LLMs are often continue pre-trained on in-domain data.…

计算与语言 · 计算机科学 2024-06-25 Xiao Liang , Xinyu Hu , Simiao Zuo , Yeyun Gong , Qiang Lou , Yi Liu , Shao-Lun Huang , Jian Jiao

Large Language Models (LLMs) have been widely applied in various professional fields. By fine-tuning the models using domain specific question and answer datasets, the professional domain knowledge and Q\&A abilities of these models have…

计算与语言 · 计算机科学 2024-07-17 Qimin Yang , Rongsheng Wang , Jiexin Chen , Runqi Su , Tao Tan

Recent advancements in large language models (LLMs) have shown promise in medical applications such as disease diagnosis and treatment planning. However, most existing medical LLMs struggle with the deep reasoning required for complex…

计算与语言 · 计算机科学 2025-07-31 Hongzhou Yu , Tianhao Cheng , Yingwen Wang , Wen He , Qing Wang , Ying Cheng , Yuejie Zhang , Rui Feng , Xiaobo Zhang

Neural Transfer Learning (TL) is becoming ubiquitous in Natural Language Processing (NLP), thanks to its high performance on many tasks, especially in low-resourced scenarios. Notably, TL is widely used for neural domain adaptation to…

计算与语言 · 计算机科学 2021-06-10 Sara Meftah , Nasredine Semmar , Youssef Tamaazousti , Hassane Essafi , Fatiha Sadat

For protein sequence datasets, unlabeled data has greatly outpaced labeled data due to the high cost of wet-lab characterization. Recent deep-learning approaches to protein prediction have shown that pre-training on unlabeled data can yield…

机器学习 · 计算机科学 2020-12-02 Pascal Sturmfels , Jesse Vig , Ali Madani , Nazneen Fatema Rajani

Medical consultation dialogues contain critical clinical information, yet their unstructured nature hinders effective utilization in diagnosis and treatment. Traditional methods, relying on rule-based or shallow machine learning techniques,…

Language models (LMs) have demonstrated remarkable capabilities in NLP, yet adapting them efficiently and robustly to specific tasks remains challenging. As their scale and complexity grow, fine-tuning LMs on labelled data often…

计算与语言 · 计算机科学 2025-06-27 Zhengyan Shi

The rapid advancement of large language models (LLMs) has significantly impacted various domains, including healthcare and biomedicine. However, the phenomenon of hallucination, where LLMs generate outputs that deviate from factual accuracy…

计算与语言 · 计算机科学 2024-08-27 Duy Khoa Pham , Bao Quoc Vo

Recent work has shown the importance of adaptation of broad-coverage contextualised embedding models on the domain of the target task of interest. Current self-supervised adaptation methods are simplistic, as the training signal comes from…

计算与语言 · 计算机科学 2020-10-06 Thuy-Trang Vu , Dinh Phung , Gholamreza Haffari

Pretraining DNA language models (DNALMs) on the full human genome is resource-intensive, yet often considered necessary for strong downstream performance. Inspired by recent findings in NLP and long-context modeling, we explore an…

基因组学 · 定量生物学 2025-06-24 Sohan Mupparapu , Parameswari Krishnamurthy , Ratish Puduppully

Language models (LMs) are pre-trained on raw text datasets to generate text sequences token-by-token. While this approach facilitates the learning of world knowledge and reasoning, it does not explicitly optimize for linguistic competence.…

计算与语言 · 计算机科学 2026-04-17 Atsuki Yamaguchi , Maggie Mi , Nikolaos Aletras

Medical multiple-choice question answering (MCQA) is particularly difficult. Questions may describe patient symptoms and ask for the correct diagnosis, which requires domain knowledge and complex reasoning. Standard language modeling…

计算与语言 · 计算机科学 2023-03-14 Damien Sileo , Kanimozhi Uma , Marie-Francine Moens

Post-training of Large Language Models (LLMs) is crucial for unlocking their task generalization potential and domain-specific capabilities. However, the current LLM post-training paradigm faces significant data challenges, including the…

计算与语言 · 计算机科学 2025-10-31 Junyu Luo , Bohan Wu , Xiao Luo , Zhiping Xiao , Yiqiao Jin , Rong-Cheng Tu , Nan Yin , Yifan Wang , Jingyang Yuan , Wei Ju , Ming Zhang

Electronic Health Records (EHRs) provide crucial information for clinical decision-making. However, their high-dimensionality, heterogeneity, and sparsity make clinical prediction challenging. Large Language Models (LLMs) allowed progress…

计算与语言 · 计算机科学 2026-01-28 Jesus Lovon-Melgarejo , Jose G. Moreno , Christine Damase-Michel , Lynda Tamine

Existing domain-specific Large Language Models (LLMs) are typically developed by fine-tuning general-purposed LLMs with large-scale domain-specific corpora. However, training on large-scale corpora often fails to effectively organize domain…

计算与语言 · 计算机科学 2025-02-11 Zhiqiang Liu , Chengtao Gan , Junjie Wang , Yichi Zhang , Zhongpu Bo , Mengshu Sun , Huajun Chen , Wen Zhang

Incremental Learning (IL) has been a long-standing problem in both vision and Natural Language Processing (NLP) communities. In recent years, as Pre-trained Language Models (PLMs) have achieved remarkable progress in various NLP downstream…

计算与语言 · 计算机科学 2024-08-09 Junhao Zheng , Shengjie Qiu , Qianli Ma

Domain-adaptive pre-training (or DA-training for short), also known as post-training, aims to train a pre-trained general-purpose language model (LM) using an unlabeled corpus of a particular domain to adapt the LM so that end-tasks in the…

计算与语言 · 计算机科学 2023-01-24 Zixuan Ke , Yijia Shao , Haowei Lin , Hu Xu , Lei Shu , Bing Liu

Large Language Models (LLMs) have demonstrated remarkable performance on various tasks, yet their ability to extract and internalize deeper insights from domain-specific datasets remains underexplored. In this study, we investigate how…

计算与语言 · 计算机科学 2025-01-30 Pouya Pezeshkpour , Estevam Hruschka

Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

计算与语言 · 计算机科学 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

Recent studies customizing Multimodal Large Language Models (MLLMs) for domain-specific tasks have yielded promising results, especially in the field of scientific chart comprehension. These studies generally utilize visual instruction…

计算机视觉与模式识别 · 计算机科学 2025-07-21 Wan-Cyuan Fan , Yen-Chun Chen , Mengchen Liu , Lu Yuan , Leonid Sigal