相关论文: Gotta be SAFE: A New Framework for Molecular Desig…

In this paper, we address the problem of having characters with different scales in scene text recognition. We propose a novel scale aware feature encoder (SAFE) that is designed specifically for encoding characters with different scales.…

Image segmentation is a popular area of research in computer vision that has many applications in automated image processing. A recent technique called piecewise flat embeddings (PFE) has been proposed for use in image segmentation; PFE…

Segment Anything (SAM) has recently pushed the boundaries of segmentation by demonstrating zero-shot generalization and flexible prompting after training on over one billion masks. Despite this, its mask prediction accuracy often falls…

Protein structure prediction often hinges on multiple sequence alignments (MSAs), which underperform on low-homology and orphan proteins. We introduce PLAME, a lightweight MSA design framework that leverages evolutionary embeddings from…

Molecular representation learning methods typically tokenize molecules as individual atoms or use rigid, rule-based fragment decompositions, limiting their ability to capture meaningful chemical substructure context. We introduce…

Textual interaction networks (TINs) are an omnipresent data structure used to model the interplay between users and items on e-commerce websites, social networks, etc., where each interaction is associated with a text description.…

Sparse autoencoders (SAEs) enable interpretability research by decomposing entangled model activations into monosemantic features. However, under what circumstances SAEs derive most fine-grained latent features for safety, a low-frequency…

Cross-lingual Speech Emotion Recognition (CLSER) aims to identify emotional states in unseen languages. However, existing methods heavily rely on the semantic synchrony of complete labels and static feature stability, hindering low-resource…

Peptide-based drugs can bind to protein interaction sites that small molecules often cannot, and are easier to produce than large protein drugs. However, designing effective peptide binders is difficult. A typical peptide has an enormous…

As the rapid development of computer vision and the emergence of powerful network backbones and architectures, the application of deep learning in medical imaging has become increasingly significant. Unlike natural images, medical images…

Understanding and predicting polymer solubility in various solvents is critical for applications ranging from recycling to pharmaceutical formulation. This work presents a deep learning framework that predicts polymer solubility, expressed…

Semantic segmentation is a computer vision task that associates a label with each pixel in an image. Modern approaches tend to introduce class embeddings into semantic segmentation for deeply utilizing category semantics, and regard…

Graph self-supervised learning (GSSL) has demonstrated strong potential for generating expressive graph embeddings without the need for human annotations, making it particularly valuable in domains with high labeling costs such as molecular…

Traditional transformer-based semantic segmentation relies on quantized embeddings. However, our analysis reveals that autoencoder accuracy on segmentation mask using quantized embeddings (e.g. VQ-VAE) is 8% lower than continuous-valued…

Segmentation is a fundamental vision task underlying numerous downstream applications. Recent promptable segmentation models, such as Segment Anything Model 3 (SAM3), extend segmentation from category-agnostic mask prediction to…

Searching for novel molecular compounds with desired properties is an important problem in drug discovery. Many existing frameworks generate molecules one atom at a time. We instead propose a flexible editing paradigm that generates…

Searching new molecules in areas like drug discovery often starts from the core structures of candidate molecules to optimize the properties of interest. The way as such has called for a strategy of designing molecules retaining a…

Deep neural networks are powerful tools for biomedical image segmentation. These models are often trained with heavy supervision, relying on pairs of images and corresponding voxel-level labels. However, obtaining segmentations of…

Modern SMILES-based chemical language models obtain strong MoleculeNet performance by treating SMILES as generic text and compensating with multi-million-molecule self-supervised pretraining. We ask: when a domain carries structural priors…

State-of-the-art semantic segmentation models are typically optimized in a data-driven fashion, minimizing solely per-pixel or per-segment classification objectives on their training data. This purely data-driven paradigm often leads to…