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We present Clinical Prediction with Large Language Models (CPLLM), a method that involves fine-tuning a pre-trained Large Language Model (LLM) for clinical disease and readmission prediction. We utilized quantization and fine-tuned the LLM…

计算与语言 · 计算机科学 2024-05-03 Ofir Ben Shoham , Nadav Rappoport

Predicting which patients are more likely to be readmitted to a hospital within 30 days after discharge is a valuable piece of information in clinical decision-making. Building a successful readmission risk classifier based on the content…

Hospital readmissions have become one of the key measures of healthcare quality. Preventable readmissions have been identified as one of the primary targets for reducing costs and improving healthcare delivery. However, most data driven…

机器学习 · 计算机科学 2018-04-05 Jialiang Jiang , Sharon Hewner , Varun Chandola

Objective: To compare different deep learning architectures for predicting the risk of readmission within 30 days of discharge from the intensive care unit (ICU). The interpretability of attention-based models is leveraged to describe…

Introduction: Timely care in a specialised neuro-intensive therapy unit (ITU) reduces mortality and hospital stays, with planned admissions being safer than unplanned ones. However, post-operative care decisions remain subjective. This…

Accurate and interpretable prediction of estimated glomerular filtration rate (eGFR) is essential for managing chronic kidney disease (CKD) and supporting clinical decisions. Recent advances in Large Multimodal Models (LMMs) have shown…

机器学习 · 计算机科学 2025-07-31 Peng-Yi Wu , Pei-Cing Huang , Ting-Yu Chen , Chantung Ku , Ming-Yen Lin , Yihuang Kang

Heart failure (HF) is one of the leading causes of hospital admissions in the US. Readmission within 30 days after a HF hospitalization is both a recognized indicator for disease progression and a source of considerable financial burden to…

机器学习 · 计算机科学 2018-12-27 Ahmed Allam , Mate Nagy , George Thoma , Michael Krauthammer

We developed an inherently interpretable multilevel Bayesian framework for representing variation in regression coefficients that mimics the piecewise linearity of ReLU-activated deep neural networks. We used the framework to formulate a…

计算机与社会 · 计算机科学 2023-01-31 Joshua C. Chang , Ted L. Chang , Carson C. Chow , Rohit Mahajan , Sonya Mahajan , Joe Maisog , Shashaank Vattikuti , Hongjing Xia

Hospital readmission has become a critical metric of quality and cost of healthcare. Medicare anticipates that nearly $17 billion is paid out on the 20% of patients who are readmitted within 30 days of discharge. Although several…

应用统计 · 统计学 2014-03-14 Issac Shams , Saeede Ajorlou , Kai Yang

Reducing potentially preventable readmissions has been identified as an important issue for decreasing Medicare costs and improving quality of care provided by hospitals. Based on previous research by medical professionals, preventable…

应用统计 · 统计学 2014-03-06 Saeede Ajorlou , Issac Shams , Kai Yang

We present a comprehensive analysis of deep learning approaches for Electronic Health Record (EHR) time-series imputation, examining how architectural and framework biases combine to influence model performance. Our investigation reveals…

机器学习 · 计算机科学 2025-02-05 Linglong Qian , Tao Wang , Jun Wang , Hugh Logan Ellis , Robin Mitra , Richard Dobson , Zina Ibrahim

Timely and interpretable early warning of sepsis remains a major clinical challenge due to the complex temporal dynamics of physiological deterioration. Traditional data-driven models often provide accurate yet opaque predictions, limiting…

机器学习 · 计算机科学 2026-04-24 Weizhi Nie , Zhen Qu , Weijie Wang , Chunpei Li , Ke Lu , Bingyang Zhou , Hongzhi Yu

Electronic health records (EHR) is an inherently multimodal register of the patient's health status characterized by static data and multivariate time series (MTS). While MTS are a valuable tool for clinical prediction, their fusion with…

In 2019, The Centers for Medicare and Medicaid Services (CMS) launched an Artificial Intelligence (AI) Health Outcomes Challenge seeking solutions to predict risk in value-based care for incorporation into CMS Innovation Center payment and…

机器学习 · 计算机科学 2021-05-21 Chuhong Lahlou , Ancil Crayton , Caroline Trier , Evan Willett

The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

机器学习 · 计算机科学 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep…

机器学习 · 计算机科学 2019-11-13 Justin R. Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

Despite the high performance of neural network-based time series forecasting methods, the inherent challenge in explaining their predictions has limited their applicability in certain application areas. Due to the difficulty in identifying…

机器学习 · 计算机科学 2023-01-09 Ozan Ozyegen , Juyoung Wang , Mucahit Cevik

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

机器学习 · 计算机科学 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Deep learning architectures have an extremely high-capacity for modeling complex data in a wide variety of domains. However, these architectures have been limited in their ability to support complex prediction problems using insurance…