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Large Language Models (LLMs) demand significant computational resources, making it essential to enhance their capabilities without retraining from scratch. A key challenge in this domain is \textit{catastrophic forgetting} (CF), which…

机器学习 · 计算机科学 2025-01-31 Haichao Wei , Yunxiang Ren , Zhoutong Fu , Aman Lunia , Yi-Lin Chen , Alice Leung , Ya Xu

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

人工智能 · 计算机科学 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

计算与语言 · 计算机科学 2025-07-10 Garapati Keerthana , Manik Gupta

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face…

计算与语言 · 计算机科学 2025-01-22 Hang Yang , Hao Chen , Hui Guo , Yineng Chen , Ching-Sheng Lin , Shu Hu , Jinrong Hu , Xi Wu , Xin Wang

Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

人工智能 · 计算机科学 2025-12-01 Niccolo Marini , Zhaohui Liang , Sivaramakrishnan Rajaraman , Zhiyun Xue , Sameer Antani

Widely used language models (LMs) are typically built by scaling up a two-stage training pipeline: a pre-training stage that uses a very large, diverse dataset of text and a fine-tuning (sometimes, 'alignment') stage that uses targeted…

计算与语言 · 计算机科学 2023-10-20 Eric Mitchell , Rafael Rafailov , Archit Sharma , Chelsea Finn , Christopher D. Manning

Clinical natural language processing requires methods that can address domain-specific challenges, such as complex medical terminology and clinical contexts. Recently, large language models (LLMs) have shown promise in this domain. Yet,…

计算与语言 · 计算机科学 2025-01-28 Ran Xu , Hejie Cui , Yue Yu , Xuan Kan , Wenqi Shi , Yuchen Zhuang , Wei Jin , Joyce Ho , Carl Yang

Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks such as medical question answering (QA). In addition, LLMs tend to function as "black-boxes", making it challenging to modify…

计算与语言 · 计算机科学 2024-08-19 Yucheng Shi , Shaochen Xu , Tianze Yang , Zhengliang Liu , Tianming Liu , Quanzheng Li , Xiang Li , Ninghao Liu

The recent success of Large Language Models (LLMs) has had a significant impact on the healthcare field, providing patients with medical advice, diagnostic information, and more. However, due to a lack of professional medical knowledge,…

计算与语言 · 计算机科学 2024-06-27 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Xiang Wan , Feng Jiang , Benyou Wang

The rapid advancement of large language models(LLMs) has prompted significant interest in their potential applications in medical domains. This paper presents a comprehensive benchmark evaluation of 27 state-of-the-art LLMs on Chinese…

General large language models (LLMs) such as ChatGPT have shown remarkable success. However, such LLMs have not been widely adopted for medical purposes, due to poor accuracy and inability to provide medical advice. We propose IvyGPT, an…

Large language models (LLMs) show promise for improving the efficiency of qualitative analysis in large, multi-site health-services research. Yet methodological guidance for LLM integration into qualitative analysis and evidence of their…

计算与语言 · 计算机科学 2026-01-22 Sasha Ronaghi , Emma-Louise Aveling , Maria Levis , Rachel Lauren Ross , Emily Alsentzer , Sara Singer

The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

计算与语言 · 计算机科学 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

The simulation of realistic clinical interactions plays a pivotal role in advancing clinical Large Language Models (LLMs) and supporting medical diagnostic education. Existing approaches and benchmarks rely on generic or LLM-generated…

计算与语言 · 计算机科学 2026-01-19 Shijie Jiang , Zefan Zhang , Kehua Zhu , Tian Bai , Ruihong Zhao

Since the rise of large language models (LLMs), the domain adaptation has been one of the hot topics in various domains. Many medical LLMs trained with English medical dataset have made public recently. However, Japanese LLMs in medical…

计算与语言 · 计算机科学 2024-06-24 Issey Sukeda , Risa Kishikawa , Satoshi Kodera

Large language models (LLMs) have become powerful tools for advancing natural language processing applications in the financial industry. However, existing financial LLMs often face challenges such as hallucinations or superficial parameter…

计算与语言 · 计算机科学 2024-08-06 Shujuan Zhao , Lingfeng Qiao , Kangyang Luo , Qian-Wen Zhang , Junru Lu , Di Yin

Models such as GPT-4 and Med-PaLM 2 have demonstrated impressive performance on a wide variety of biomedical NLP tasks. However, these models have hundreds of billions of parameters, are computationally expensive to run, require users to…

Large language models (LLMs) are increasingly adopted in clinical decision support, yet aligning them with the multifaceted reasoning pathways of real-world medicine remains a major challenge. Using more than 8,000 infertility treatment…

机器学习 · 计算机科学 2025-11-25 Dou Liu , Ying Long , Sophia Zuoqiu , Kaipeng Xie , Runze Yang , Di Liu , Kang Li , Yiting Lin , Hanyi Liu , Rong Yin , Tian Tang

Despite the significant improvements achieved by large language models (LLMs) in English reasoning tasks, these models continue to struggle with multilingual reasoning. Recent studies leverage a full-parameter and two-stage training…

计算与语言 · 计算机科学 2025-01-08 Yuchun Fan , Yongyu Mu , Yilin Wang , Lei Huang , Junhao Ruan , Bei Li , Tong Xiao , Shujian Huang , Xiaocheng Feng , Jingbo Zhu

In recent years, there has been substantial progress in using pretrained Language Models (LMs) on a range of tasks aimed at improving the understanding of biomedical texts. Nonetheless, existing biomedical LLMs show limited comprehension of…

计算与语言 · 计算机科学 2025-09-10 Andrey Sakhovskiy , Elena Tutubalina
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