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Lung cancer (LC) ranks among the most frequently diagnosed cancers and is one of the most common causes of death for men and women worldwide. Computed Tomography (CT) images are the most preferred diagnosis method because of their low cost…

图像与视频处理 · 电气工程与系统科学 2025-08-11 Mobarak Abumohsen , Enrique Costa-Montenegro , Silvia García-Méndez , Amani Yousef Owda , Majdi Owda

Autopsy studies of adults dying of non-cancer causes have shown that virtually all of us possess occult, cancerous lesions. This suggests that, for most individuals, cancer will become dormant and not progress, while only in some will it…

定量方法 · 定量生物学 2014-06-06 Sébastien Benzekry , Alberto Gandolfi , Philip Hahnfeldt

Lung cancer, a severe form of malignant tumor that originates in the tissues of the lungs, can be fatal if not detected in its early stages. It ranks among the top causes of cancer-related mortality worldwide. Detecting lung cancer manually…

计算机视觉与模式识别 · 计算机科学 2025-04-22 Santanu Roy , Shweta Singh , Palak Sahu , Ashvath Suresh , Debashish Das

Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

计算机视觉与模式识别 · 计算机科学 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…

Tumor shape is a key factor that affects tumor growth and metastasis. This paper proposes a topological feature computed by persistent homology to characterize tumor progression from digital pathology and radiology images and examines its…

计算机视觉与模式识别 · 计算机科学 2023-03-01 Chul Moon , Qiwei Li , Guanghua Xiao

Until the beginning of 2021, lung cancer is known to be the most common cancer in the world. The disease is common due to factors such as occupational exposure, smoking and environmental pollution. The early diagnosis and treatment of the…

机器学习 · 计算机科学 2021-05-21 Asim Leblebici , Omer Gesoglu , Yasemin Basbinar

Lung cancer is the primary cause of cancer-related mortality, claiming approximately 1.79 million lives globally in 2020, with an estimated 2.21 million new cases diagnosed within the same period. Among these, Non-Small Cell Lung Cancer…

定量方法 · 定量生物学 2024-02-16 Mahtab Darvish , Ryan Trask , Patrick Tallon , Mélina Khansari , Lei Ren , Michelle Hershman , Bardia Yousefi

Metastatic Progression remains the leading cause of cancer-related mortality, yet predicting whether a primary tumor will metastasize and where it will disseminate directly from histopathology remains a fundamental challenge. Although…

计算机视觉与模式识别 · 计算机科学 2026-05-07 Yixin Chen , Ziyu Su , Lingbin Meng , Elshad Hasanov , Wei Chen , Anil Parwani , M. Khalid Khan Niazi

Disease maps are an important tool in cancer epidemiology used for the analysis of geographical variations in disease rates and the investigation of environmental risk factors underlying spatial patterns. Cancer maps help epidemiologists…

应用统计 · 统计学 2020-12-08 Leiwen Gao , Sudipto Banerjee , Abhirup Datta

Background: Stratifying cancer patients according to risk of relapse can personalize their care. In this work, we provide an answer to the following research question: How to utilize machine learning to estimate probability of relapse in…

Lung cancer is a major issue in worldwide public health, requiring early diagnosis using stable techniques. This work begins a thorough investigation of the use of machine learning (ML) methods for precise classification of lung cancer…

计算机视觉与模式识别 · 计算机科学 2025-01-31 Shayli Farshchiha , Salman Asoudeh , Maryam Shavali Kuhshuri , Mehrshad Eisaeid , Mohamadreza Azadie , Saba Hesaraki

Lung cancer, particularly in its advanced stages, remains a leading cause of death globally. Though early detection via low-dose computed tomography (CT) is promising, the identification of high-risk factors crucial for surgical mode…

图像与视频处理 · 电气工程与系统科学 2023-08-29 Xiaotong Fu , Xiangyu Meng , Jing Zhou , Ying Ji

Metastatic presence in lymph nodes is one of the most important prognostic variables of breast cancer. The current diagnostic procedure for manually reviewing sentinel lymph nodes, however, is very time-consuming and subjective.…

计算机视觉与模式识别 · 计算机科学 2016-08-05 Richard Chen , Yating Jing , Hunter Jackson

Understanding the progression of cancer is crucial for defining treatments for patients. The objective of this study is to automate the detection of metastatic liver disease from free-style computed tomography (CT) radiology reports. Our…

机器学习 · 计算机科学 2023-10-31 Maede Ashofteh Barabadi , Xiaodan Zhu , Wai Yip Chan , Amber L. Simpson , Richard K. G. Do

The spatial distributions of different types of cells could reveal a cancer cell growth pattern, its relationships with the tumor microenvironment and the immune response of the body, all of which represent key hallmarks of cancer. However,…

计算机视觉与模式识别 · 计算机科学 2018-09-28 Shidan Wang , Tao Wang , Lin Yang , Faliu Yi , Xin Luo , Yikun Yang , Adi Gazdar , Junya Fujimoto , Ignacio I. Wistuba , Bo Yao , ShinYi Lin , Yang Xie , Yousheng Mao , Guanghua Xiao

Metastasis is the leading cause of cancer-related mortality, yet most predictive models rely on shallow architectures and neglect patient-specific regulatory mechanisms. Here, we integrate classical machine learning and deep learning to…

其他定量生物学 · 定量生物学 2025-12-29 Jiwei Fu , Chunyu Yang

Lung cancer remains one of the leading causes of cancer-related mortality, yet most survival models rely only on baseline factors and overlook posttreatment variables that reflect disease progression. To address this gap, we applied Cox…

应用统计 · 统计学 2025-10-03 Varun Vishwanathan Nair , Victor Miranda Soberanis

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

图像与视频处理 · 电气工程与系统科学 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

Lung adenocarcinoma is a morphologically heterogeneous disease, characterized by five primary histologic growth patterns. The quantity of these patterns can be related to tumor behavior and has a significant impact on patient prognosis. In…

图像与视频处理 · 电气工程与系统科学 2024-05-17 Arwa Al-Rubaian , Gozde N. Gunesli , Wajd A. Althakfi , Ayesha Azam , Nasir Rajpoot , Shan E Ahmed Raza