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Controlling the False Discovery Rate (FDR) in a variable selection procedure is critical for reproducible discoveries, and it has been extensively studied in sparse linear models. However, it remains largely open in scenarios where the…

统计方法学 · 统计学 2023-11-16 Yang Cao , Xinwei Sun , Yuan Yao

Controlling the False Discovery Rate (FDR) is critical for reproducible variable selection, especially given the prevalence of complex predictive modeling. The recent Split Knockoff method, an extension of the canonical Knockoffs framework,…

统计方法学 · 统计学 2025-09-05 Yang Cao , Hangyu Lin , Xinwei Sun , Yuan Yao

This paper develops a framework for testing for associations in a possibly high-dimensional linear model where the number of features/variables may far exceed the number of observational units. In this framework, the observations are split…

统计方法学 · 统计学 2018-05-04 Rina Foygel Barber , Emmanuel J. Candes

Continuous improvement in medical imaging techniques allows the acquisition of higher-resolution images. When these are used in a predictive setting, a greater number of explanatory variables are potentially related to the dependent…

统计理论 · 数学 2019-03-13 Tuan-Binh Nguyen , Jérôme-Alexis Chevalier , Bertrand Thirion

Controlling false discovery rate (FDR) is crucial for variable selection, multiple testing, among other signal detection problems. In literature, there is certainly no shortage of FDR control strategies when selecting individual features,…

统计方法学 · 统计学 2022-04-11 Jingyuan Liu , Ao Sun , Yuan Ke

Selecting important features that have substantial effects on the response with provable type-I error rate control is a fundamental concern in statistics, with wide-ranging practical applications. Existing knockoff filters, although shown…

统计方法学 · 统计学 2024-02-29 Jiaqi Gu , Zihuai He

The false discovery rate (FDR)---the expected fraction of spurious discoveries among all the discoveries---provides a popular statistical assessment of the reproducibility of scientific studies in various disciplines. In this work, we…

机器学习 · 统计学 2015-11-10 Weijie Su , Junyang Qian , Linxi Liu

Alzheimer's detection efforts aim to develop accurate models for early disease diagnosis. Significant advances have been achieved with convolutional neural networks and vision transformer based approaches. However, medical datasets suffer…

计算机视觉与模式识别 · 计算机科学 2025-05-29 Zobia Batool , Huseyin Ozkan , Erchan Aptoula

With the increasing amounts of high-dimensional heterogeneous data to be processed, multi-modality feature selection has become an important research direction in medical image analysis. Traditional methods usually depict the data structure…

计算机视觉与模式识别 · 计算机科学 2022-04-11 Yuang Shi , Chen Zu , Mei Hong , Luping Zhou , Lei Wang , Xi Wu , Jiliu Zhou , Daoqiang Zhang , Yan Wang

Testing multiple hypotheses of conditional independence with provable error rate control is a fundamental problem with various applications. To infer conditional independence with family-wise error rate (FWER) control when only summary…

统计方法学 · 统计学 2023-10-17 Catherine Xinrui Yu , Jiaqi Gu , Zhaomeng Chen , Zihuai He

We introduce a novel framework for the classification of functional data supported on nonlinear, and possibly random, manifold domains. The motivating application is the identification of subjects with Alzheimer's disease from their…

统计方法学 · 统计学 2024-04-15 Eardi Lila , Wenbo Zhang , Swati Rane Levendovszky

Simultaneously performing variable selection and inference in high-dimensional regression models is an open challenge in statistics and machine learning. The increasing availability of vast amounts of variables requires the adoption of…

统计方法学 · 统计学 2025-05-08 Marco Molinari , Magne Thoresen

In many fields of science, we observe a response variable together with a large number of potential explanatory variables, and would like to be able to discover which variables are truly associated with the response. At the same time, we…

统计方法学 · 统计学 2015-10-15 Rina Foygel Barber , Emmanuel J. Candès

Recent research in neuroimaging has focused on assessing associations between genetic variants that are measured on a genomewide scale and brain imaging phenotypes. A large number of works in the area apply massively univariate analyses on…

Model-free knockoffs is a recently proposed technique for identifying covariates that is likely to have an effect on a response variable. The method is an efficient method to control the false discovery rate in hypothesis tests for separate…

统计方法学 · 统计学 2019-03-29 Lars Holden , Kristoffer Hellton

Variable selection has been widely used in data analysis for the past decades, and it becomes increasingly important in the Big Data era as there are usually hundreds of variables available in a dataset. To enhance interpretability of a…

统计方法学 · 统计学 2020-08-17 Yuxiang Xie , Kwun Chuen Gary Chan

False discovery rate (FDR) control methods are essential for voxel-wise multiple testing in neuroimaging data analysis, where hundreds of thousands or even millions of tests are conducted to detect brain regions associated with…

机器学习 · 统计学 2025-05-30 Taehyo Kim , Qiran Jia , Mony J. de Leon , Hai Shu

Barber and Candes recently introduced a feature selection method called knockoff+ that controls the false discovery rate (FDR) among the selected features in the classical linear regression problem. Knockoff+ uses the competition between…

统计方法学 · 统计学 2019-11-25 Kristen Emery , Uri Keich

False discovery rate (FDR) is commonly used for correction for multiple testing in neuroimaging studies. However, when using two-tailed tests, making directional inferences about the results can lead to a vastly inflated error rate, even…

统计方法学 · 统计学 2025-12-16 Anderson M. Winkler , Paul A. Taylor , Thomas E. Nichols , Chris Rorden

Traditional voxel-level multiple testing procedures in neuroimaging, mostly $p$-value based, often ignore the spatial correlations among neighboring voxels and thus suffer from substantial loss of power. We extend the…

应用统计 · 统计学 2016-07-29 Hai Shu , Bin Nan , Robert Koeppe
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