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Synthetic generation of three-dimensional cell models from histopathological images aims to enhance understanding of cell mutation, and progression of cancer, necessary for clinical assessment and optimal treatment. Classical reconstruction…

图像与视频处理 · 电气工程与系统科学 2021-02-09 Yoav Alon , Xiang Yu , Huiyu Zhou

Graph generation has emerged as a crucial task in machine learning, with significant challenges in generating graphs that accurately reflect specific properties. Existing methods often fall short in efficiently addressing this need as they…

Diffusion models have become a new SOTA generative modeling method in various fields, for which there are multiple survey works that provide an overall survey. With the number of articles on diffusion models increasing exponentially in the…

机器学习 · 计算机科学 2023-04-05 Mengchun Zhang , Maryam Qamar , Taegoo Kang , Yuna Jung , Chenshuang Zhang , Sung-Ho Bae , Chaoning Zhang

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

图像与视频处理 · 电气工程与系统科学 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Deep learning has proven to yield fast and accurate predictions of quantum-chemical properties to accelerate the discovery of novel molecules and materials. As an exhaustive exploration of the vast chemical space is still infeasible, we…

机器学习 · 统计学 2020-01-10 Niklas W. A. Gebauer , Michael Gastegger , Kristof T. Schütt

The lack of analytical models describing diffusion time dependence at intermediate time scales in complex tissue microstructure limits the accurate quantification of extracellular diffusivity and tissue microstructure. We introduce TRACED,…

Glioblastoma exhibits diverse, infiltrative, and patient-specific growth patterns that are only partially visible on routine MRI, making it difficult to reliably assess true tumor extent and personalize treatment planning and follow-up. We…

计算机视觉与模式识别 · 计算机科学 2026-03-06 Valentin Biller , Niklas Bubeck , Lucas Zimmer , Ayhan Can Erdur , Sandeep Nagar , Anke Meyer-Baese , Daniel Rückert , Benedikt Wiestler , Jonas Weidner

Deep generative models can emulate the perceptual properties of complex image datasets, providing a latent representation of the data. However, manipulating such representation to perform meaningful and controllable transformations in the…

机器学习 · 计算机科学 2019-12-13 Michel Besserve , Arash Mehrjou , Rémy Sun , Bernhard Schölkopf

Temporal graphs represent the dynamic relationships among entities and occur in many real life application like social networks, e commerce, communication, road networks, biological systems, and many more. They necessitate research beyond…

机器学习 · 计算机科学 2022-08-26 Shubham Gupta , Srikanta Bedathur

Application of deep learning in digital pathology shows promise on improving disease diagnosis and understanding. We present a deep generative model that learns to simulate high-fidelity cancer tissue images while mapping the real images…

图像与视频处理 · 电气工程与系统科学 2020-04-15 Adalberto Claudio Quiros , Roderick Murray-Smith , Ke Yuan

The presence of tertiary lymphoid structures (TLSs) on pancreatic pathological images is an important prognostic indicator of pancreatic tumors. Therefore, TLSs detection on pancreatic pathological images plays a crucial role in diagnosis…

图像与视频处理 · 电气工程与系统科学 2023-07-28 Bingxue Wang , Liwen Zou , Jun Chen , Yingying Cao , Zhenghua Cai , Yudong Qiu , Liang Mao , Zhongqiu Wang , Jingya Chen , Luying Gui , Xiaoping Yang

Biological networks are one of the most studied object in computational biology. Several methods have been developed for studying qualitative properties of biological networks. Last decade had seen the improvement of molecular techniques…

定量方法 · 定量生物学 2016-08-14 Jérémie Bourdon , Damien Eveillard

We consider multivariate two-sample tests of means, where the location shift between the two populations is expected to be related to a known graph structure. An important application of such tests is the detection of differentially…

定量方法 · 定量生物学 2014-05-16 Laurent Jacob , Pierre Neuvial , Sandrine Dudoit

Molecular graphs generally contain subgraphs (known as groups) that are identifiable and significant in composition, functionality, geometry, etc. Flat latent representations (node embeddings or graph embeddings) fail to represent, and…

机器学习 · 计算机科学 2019-04-05 Daniel T. Chang

Deep graph generative modeling has proven capable of learning the distribution of complex, multi-scale structures characterizing real-world graphs. However, one of the main limitations of existing methods is their large output space, which…

机器学习 · 计算机科学 2023-06-01 Nathaniel Diamant , Alex M. Tseng , Kangway V. Chuang , Tommaso Biancalani , Gabriele Scalia

Generative tasks about molecules, including but not limited to molecule generation, are crucial for drug discovery and material design, and have consistently attracted significant attention. In recent years, diffusion models have emerged as…

机器学习 · 计算机科学 2025-02-14 Liang Wang , Chao Song , Zhiyuan Liu , Yu Rong , Qiang Liu , Shu Wu , Liang Wang

Graph neural network models have been extensively used to learn node representations for graph structured data in an end-to-end setting. These models often rely on localized first order approximations of spectral graph convolutions and…

机器学习 · 计算机科学 2020-10-20 Mohammed Haroon Dupty , Wee Sun Lee

The development of robust deep learning models for breast ultrasound (BUS) image analysis is significantly constrained by the scarcity of expert-annotated data. To address this limitation, we propose a clinically controllable generative…

图像与视频处理 · 电气工程与系统科学 2025-07-11 Haoyu Pan , Hongxin Lin , Zetian Feng , Chuxuan Lin , Junyang Mo , Chu Zhang , Zijian Wu , Yi Wang , Qingqing Zheng

In this paper, we present a survey of the use of graph theoretical techniques in Biology. In particular, we discuss recent work on identifying and modelling the structure of bio-molecular networks, as well as the application of centrality…

分子网络 · 定量生物学 2007-05-23 Oliver Mason , Mark Verwoerd

Diffusion models are a special type of generative model, capable of synthesising new data from a learnt distribution. We introduce DISPR, a diffusion-based model for solving the inverse problem of three-dimensional (3D) cell shape…

计算机视觉与模式识别 · 计算机科学 2023-03-15 Dominik J. E. Waibel , Ernst Röell , Bastian Rieck , Raja Giryes , Carsten Marr