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Graphical model estimation from multi-omics data requires a balance between statistical estimation performance and computational scalability. We introduce a novel pseudolikelihood-based graphical model framework that reparameterizes the…

机器学习 · 统计学 2025-09-23 Sungdong Lee , Joshua Bang , Youngrae Kim , Hyungwon Choi , Sang-Yun Oh , Joong-Ho Won

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

神经与进化计算 · 计算机科学 2024-01-12 Abeer Dyoub , Ivan Letteri

We develop and validate a novel spherical radiomics framework for predicting key molecular biomarkers using multiparametric MRI. Conventional Cartesian radiomics extract tumor features on orthogonal grids, which do not fully capture the…

医学物理 · 物理学 2025-10-22 Haotian Feng , Ke Sheng

In this chapter we illustrate the use of some Machine Learning techniques in the context of omics data. More precisely, we review and evaluate the use of Random Forest and Penalized Multinomial Logistic Regression for integrative analysis…

基因组学 · 定量生物学 2024-02-09 Aida Calviño , Almudena Moreno-Ribera , Silvia Pineda

When oncologists estimate cancer patient survival, they rely on multimodal data. Even though some multimodal deep learning methods have been proposed in the literature, the majority rely on having two or more independent networks that share…

图像与视频处理 · 电气工程与系统科学 2022-09-13 Numan Saeed , Ikboljon Sobirov , Roba Al Majzoub , Mohammad Yaqub

Small data learning problems are characterized by a significant discrepancy between the limited amount of response variable observations and the large feature space dimension. In this setting, the common learning tools struggle to identify…

机器学习 · 计算机科学 2023-10-31 Edoardo Vecchi , Davide Bassetti , Fabio Graziato , Lukas Pospisil , Illia Horenko

Aim: In the present work, we aimed to evaluate a comprehensive radiomics framework that enabled prediction of EGFR and KRAS mutation status in NSCLC cancer patients based on PET and CT multi-modalities radiomic features and machine learning…

Causal effect estimation is a critical task in statistical learning that aims to find the causal effect on subjects by identifying causal links between a number of predictor (or, explanatory) variables and the outcome of a treatment. In a…

统计方法学 · 统计学 2024-11-26 Tathagata Basu , Matthias C. M. Troffaes

Image classification is widely used to build predictive models for breast cancer diagnosis. Most existing approaches overwhelmingly rely on deep convolutional networks to build such diagnosis pipelines. These model architectures, although…

图像与视频处理 · 电气工程与系统科学 2022-01-20 Alireza Rezazadeh , Yasamin Jafarian , Ali Kord

Lung cancer is one of the deadliest diseases and the leading cause of illness and death. Since lung cancer cannot predicted at premature stage, it able to only be discovered more broadly once it has spread to other lung parts. The risk…

图像与视频处理 · 电气工程与系统科学 2023-12-07 V S Priya Sumitha , V. Keerthika , A. Geetha

A significant challenge in solid tumors is reliably distinguishing confounding pathologies from malignant neoplasms on routine imaging. While radiomics methods seek surrogate markers of lesion heterogeneity on CT/MRI, many aggregate…

Causal discovery methods can identify valid adjustment sets for causal effect estimation for a pair of target variables, even when the underlying causal graph is unknown. Global causal discovery methods focus on learning the whole causal…

机器学习 · 统计学 2026-04-01 Mátyás Schubert , Tom Claassen , Sara Magliacane

Algorithm selection (AS) deals with selecting an algorithm from a fixed set of candidate algorithms most suitable for a specific instance of an algorithmic problem, e.g., choosing solvers for SAT problems. Benchmark suites for AS usually…

机器学习 · 计算机科学 2020-10-23 Alexander Tornede , Marcel Wever , Eyke Hüllermeier

Nowadays, Breast cancer has risen to become one of the most prominent causes of death in recent years. Among all malignancies, this is the most frequent and the major cause of death for women globally. Manually diagnosing this disease…

机器学习 · 计算机科学 2022-07-01 Taminul Islam , Arindom Kundu , Nazmul Islam Khan , Choyon Chandra Bonik , Flora Akter , Md Jihadul Islam

The main objective of this work is to accelerate the Maximum-Likelihood (ML) estimation procedure in radio interferometric calibration. We introduce the OS-LS and the OS-SAGE radio interferometric calibration methods, as a combination of…

天体物理仪器与方法 · 物理学 2015-06-16 S. Kazemi , S. Yatawatta , S. Zaroubi

Glioblastoma is profoundly heterogeneous in microstructure and vasculature, which may lead to tumor regional diversity and distinct treatment response. Although successful in tumor sub-region segmentation and survival prediction, radiomics…

图像与视频处理 · 电气工程与系统科学 2021-09-30 Yifan Li , Chao Li , Stephen Price , Carola-Bibiane Schönlieb , Xi Chen

Objective: Radiomics-driven Computer Aided Diagnosis (CAD) has shown considerable promise in recent years as a potential tool for improving clinical decision support in medical oncology, particularly those based around the concept of…

人工智能 · 计算机科学 2017-10-31 Devinder Kumar , Graham W. Taylor , Alexander Wong

3D computer-assisted corrective osteotomy has become the state-of-the-art for surgical treatment of complex bone deformities. Despite available technologies, the automatic generation of clinically acceptable, ready-to-use preoperative…

As a means to extract biomarkers from medical imaging, radiomics has attracted increased attention from researchers. However, reproducibility and performance of radiomics in low dose CT scans are still poor, mostly due to noise. Deep…

定量方法 · 定量生物学 2021-09-17 Junhua Chen , Leonard Wee , Andre Dekker , Inigo Bermejo

Invasive ductal carcinoma is a prevalent, potentially deadly disease associated with a high rate of morbidity and mortality. Its malignancy is the second leading cause of death from cancer in women. The mammogram is an extremely useful…

计算机视觉与模式识别 · 计算机科学 2021-11-09 Rushabh Patel