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Swimming eukaryotic microorganisms such as spermatozoa, algae and ciliates self-propel in viscous fluids using travelling wave-like deformations of slender appendages called flagella. Waves are predominant because Purcell's scallop theorem…

流体动力学 · 物理学 2020-11-18 Eric Lauga

Many eukaryotic cells use the active waving motion of flexible flagella to self-propel in viscous fluids. However, the criteria governing the selection of particular flagellar waveforms among all possible shapes has proved elusive so far.…

生物物理 · 物理学 2013-08-02 Christophe Eloy , Eric Lauga

Several micro-organisms, such as bacteria, algae, or spermatozoa, use flagella or cilia to swim in a fluid, while many other micro-organisms instead use ample shape deformation, described as amoeboid, to propel themselves by either crawling…

生物物理 · 物理学 2016-09-19 Hao Wu , A. Farutin , W. -F. Hu , M. Thiébaud , S. Rafaï , P. Peyla , M. -C. Lai , C. Misbah

Eukaryotic cell motility is crucial during development, wound healing, the immune response, and cancer metastasis. Some eukaryotic cells can swim, but cells more commonly adhere to and crawl along the extracellular matrix. We study the…

细胞行为 · 定量生物学 2019-09-02 Melissa H. Mai , Brian A. Camley

Recent research has shown that motile cells can adapt their mode of propulsion to the mechanical properties of the environment in which they find themselves--crawling in some environments while swimming in others. The latter can involve…

生物物理 · 物理学 2018-05-24 Hao Wu , Marco Avila Ponce de Leon , Hans G. Othmer

The motility of microorganisms is influenced greatly by their hydrodynamic interactions with the fluidic environment they inhabit. We show by direct experimental observation of the bi-flagellated alga Chlamydomonas reinhardtii that fluid…

生物物理 · 物理学 2015-11-03 Boyang Qin , Arvind Gopinath , Jing Yang , Jerry P Gollub , Paulo E Arratia

The swimming properties of an E. coli-type model bacterium are investigated by mesoscale hy- drodynamic simulations, combining molecular dynamics simulations of the bacterium with the multiparticle particle collision dynamics method for the…

软凝聚态物质 · 物理学 2016-08-23 Jinglei Hu , Mingcheng Yang , Gerhard Gompper , Roland G. Winkler

The propulsion of many eukaryotic cells is generated by flagella, flexible slender filaments that are actively oscillating in space and time. The dynamics of these biological appendages have inspired the design of many types of artificial…

软凝聚态物质 · 物理学 2025-04-15 Mariia Dvoriashyna , Eric Lauga

Unicellular microscopic organisms living in aqueous environments outnumber all other creatures on Earth. A large proportion of them are able to self-propel in fluids with a vast diversity of swimming gaits and motility patterns. In this…

生物物理 · 物理学 2021-07-14 Marcos F. Velho Rodrigues , Maciej Lisicki , Eric Lauga

Interactions between swimming cells and surfaces are essential to many microbiological processes, from bacterial biofilm formation to human fertilization. However, in spite of their fundamental importance, relatively little is known about…

生物物理 · 物理学 2013-02-04 Vasily Kantsler , Jörn Dunkel , Marco Polin , Raymond E. Goldstein

Motile eukaryotic cells propel themselves in viscous fluids by passing waves of bending deformation down their flagella. An infinitely long flagellum achieves a hydrodynamically optimal low-Reynolds number locomotion when the angle between…

生物物理 · 物理学 2010-03-03 Saverio E. Spagnolie , Eric Lauga

The intricate wobbling motion of flagellated bacteria, characterized by the periodic precession of the cell body, is a determinant factor in their motility and navigation within complex fluid environments. While well-studied in quiescent…

软凝聚态物质 · 物理学 2026-01-26 Wei Feng , Fanglong Dang , Hao Luo , Alan C. H. Tsang , Yanan Liu , Guangyin Jing

Cilia and flagella are actively bending slender organelles, performing functions such as motility, feeding and embryonic symmetry breaking. We review the mechanics of viscous-dominated microscale flow, including time-reversal symmetry, drag…

定量方法 · 定量生物学 2013-09-06 Thomas D. Montenegro-Johnson , Andrew A. Smith , David J. Smith , Daniel Loghin , John R. Blake

Cell motility in viscous fluids is ubiquitous and affects many biological processes, including reproduction, infection, and the marine life ecosystem. Here we review the biophysical and mechanical principles of locomotion at the small…

软凝聚态物质 · 物理学 2009-09-16 Eric Lauga , Thomas R. Powers

Cells swimming in confined environments are attracted by surfaces. We measure the steady-state distribution of smooth-swimming bacteria (Escherichia coli) between two glass plates. In agreement with earlier studies, we find a strong…

软凝聚态物质 · 物理学 2008-10-02 Allison P. Berke , Linda Turner , Howard C. Berg , Eric Lauga

Eukaryote cells have a flexible shape, which dynamically changes according to the function performed by the cell. One mechanism for deforming the cell membrane into the desired shape is through the expression of curved membrane proteins.…

生物物理 · 物理学 2018-12-05 Miha Fošnarič , Samo Penič , Aleš Iglič , Veronika Kralj-Iglič , Mitja Drab , Nir Gov

A variety of swimming microorganisms, called ciliates, exploit the bending of a large number of small and densely-packed organelles, termed cilia, in order to propel themselves in a viscous fluid. We consider a spherical envelope model for…

流体动力学 · 物理学 2011-08-30 Sebastien Michelin , Eric Lauga

Some microorganisms, such as spermatozoa, synchronize their flagella when swimming in close proximity. Using a simplified model (two infinite, parallel, two-dimensional waving sheets), we show that phase-locking arises from hydrodynamics…

生物物理 · 物理学 2009-09-15 Gwynn J. Elfring , Eric Lauga

Although the motility of the flagellated bacteria, Escherichia coli, has been widely studied, the effect of viscosity on swimming speed remains controversial. The swimming mode of wild-type E.coli is often idealized as a "run-and- tumble"…

生物物理 · 物理学 2018-05-09 Zijie Qu , Fatma Zeynep Temel , Rene Henderikx , Kenneth S. Breuer

In a variety of biological processes, eukaryotic cells use cilia to transport flow. Although cilia have a remarkably conserved internal molecular structure, experimental observations report very diverse kinematics. To address this…

生物物理 · 物理学 2012-07-19 Christophe Eloy , Eric Lauga
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