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In recent years, machine learning has become an increasingly powerful tool for supporting seizure detection and monitoring in epilepsy care. Traditional approaches focus on identifying seizures only after they begin, which limits the…

机器学习 · 计算机科学 2025-10-30 Ria Jayanti , Tanish Jain

In this work we investigate time varying networks with complex dynamics at the nodes. We consider two scenarios of network change in an interval of time: first, we have the case where each link can change with probability pt, i.e. the…

适应与自组织系统 · 物理学 2014-04-14 Ankit Kumar , Vidit Agrawal , Sudeshna Sinha

Epilepsy represents the most prevalent neurological disease in the world. One-third of people suffering from mesial temporal lobe epilepsy (MTLE) exhibit drug resistance, urging the need to develop new treatments. A key part in anti-seizure…

The presence of spikes and sharp waves in the recordings of epileptic patients may contaminate background signal synchronization in different ways. In this Technical Note, we present a simple procedure for assessing whether a particular…

神经元与认知 · 定量生物学 2012-11-27 Jesús Pastor , Guillermo Ortega

Accurate prediction of epileptic seizures has remained elusive, despite the many advances in machine learning and time-series classification. In this work, we develop a convolutional network module that exploits Electroencephalogram (EEG)…

图像与视频处理 · 电气工程与系统科学 2020-07-24 Ramy Hussein , Soojin Lee , Rabab Ward , Martin J. McKeown

Over the last years, increasing evidence has fuelled the hypothesis that Autism Spectrum Disorder (ASD) is a condition of altered brain functional connectivity. The great majority of these empirical studies rely on functional magnetic…

神经元与认知 · 定量生物学 2010-08-02 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Mariano Sigman

Detection of nocturnal seizures in epilepsy patients is essential, both for the quick management of the seizure complications, and for the assessment of the ongoing seizure treatment. Traditional seizure detection products (e.g.,…

信号处理 · 电气工程与系统科学 2021-07-29 Belal Korany , Yasamin Mostofi

Synchronous oscillatory dynamics is frequently observed in the human brain. We analyze the fine temporal structure of phase-locking in a realistic network model and match it with the experimental data from parkinsonian patients. We show…

神经元与认知 · 定量生物学 2011-04-18 Choongseok Park , Robert M. Worth , Leonid L. Rubchinsky

Understanding the neural mechanisms underlying the transitions between different states of consciousness is a fundamental challenge in neuroscience. Thus, we investigate the underlying drivers of changes during the resting-state dynamics of…

神经元与认知 · 定量生物学 2024-07-10 Joseph Bodenheimer , Paul Bogdan , Sérgio Pequito , Arian Ashourvan

Complex spatiotemporal patterns, called chimera states, consist of coexisting coherent and incoherent domains and can be observed in networks of coupled oscillators. The interplay of synchrony and asynchrony in complex brain networks is an…

适应与自组织系统 · 物理学 2019-06-20 Teresa Chouzouris , Iryna Omelchenko , Anna Zakharova , Jaroslav Hlinka , Premysl Jiruska , Eckehard Schöll

We present an interacting branching model of neural network dynamics, incorporating key biological features such as inhibition with several types of inhibitory interactions. We establish a hierarchy of analytical mean-field approximations…

无序系统与神经网络 · 物理学 2025-12-29 Jeremy B. Goetz , Naruepon Weerawongphrom , Rashid V. Williams-García , John M. Beggs , Gerardo Ortiz

Epileptic seizure detection from EEG signals remains challenging due to the high dimensionality and nonlinear, potentially stochastic, dynamics of neural activity. In this work, we investigate whether features derived from topological data…

机器学习 · 计算机科学 2026-04-15 Sunia Tanweer , Narayan Puthanmadam Subramaniyam , Firas A. Khasawneh

Electroencephalogram (EEG) is a common tool used to understand brain activities. The data are typically obtained by placing electrodes at the surface of the scalp and recording the oscillations of currents passing through the electrodes.…

信号处理 · 电气工程与系统科学 2021-02-19 Eddy Kwessi , Lloyd Edwards

Interictal spikes and sharp waves in human EEG are characteristic signatures of epilepsy. These potentials originate as a result of synchronous, pathological discharge of many neurons. The reliable detection of such potentials has been the…

生物物理 · 物理学 2009-11-10 Miroslaw Latka , Ziemowit Was , Andrzej Kozik , Bruce J. West

Classification of seizure type is a key step in the clinical process for evaluating an individual who presents with seizures. It determines the course of clinical diagnosis and treatment, and its impact stretches beyond the clinical domain…

信号处理 · 电气工程与系统科学 2024-03-06 David Ahmedt-Aristizabal , Tharindu Fernando , Simon Denman , Lars Petersson , Matthew J. Aburn , Clinton Fookes

Epilepsy is recognised as a dynamic disease, where both seizure susceptibility and seizure characteristics themselves change over time. Specifically, we recently quantified the variable electrographic spatio-temporal seizure evolutions that…

Most brain disorders including Alzheimer's disease (AD) are related to alterations in the normal brain network organization and function. Exploring these network alterations using non-invasive and easy to use technique is a topic of great…

神经元与认知 · 定量生物学 2017-06-14 Aya Kabbara , Mahmoud Hassan , Mohamad Khalil , Wassim El Falou , Hassan Eid

Complex spatial connectivity patterns, such as interictal suppression and ictal propagation, complicate accurate drug-resistant epilepsy (DRE) seizure detection using stereotactic electroencephalography (SEEG) and traditional machine…

信号处理 · 电气工程与系统科学 2025-12-03 Yiping Wang , Peiren Wang , Zhenye Li , Fang Liu , Jinguo Huang

Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…

神经元与认知 · 定量生物学 2022-08-15 Ganchao Wei , Ian H. Stevenson

Epilepsy is a disorder of the nervous system that can affect people of any age group. With roughly 50 million people worldwide diagnosed with the disorder, it is one of the most common neurological disorders. The EEG is an indispensable…

种群与进化 · 定量生物学 2022-02-21 Niamh McCallan , Scot Davidson , Kok Yew Ng , Pardis Biglarbeigi , Dewar Finlay , Boon Leong Lan , James McLaughlin