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On surfaces with many motile cilia, beats of the individual cilia coordinate to form metachronal waves. We present a theoretical framework that connects the dynamics of an individual cilium to the collective dynamics of a ciliary carpet via…

软凝聚态物质 · 物理学 2021-03-12 Fanlong Meng , Rachel R. Bennett , Nariya Uchida , Ramin Golestanian

Microorganisms develop coordinated beating patterns on surfaces lined with cilia known as metachronal waves. For a chain of cilia attached to a flat ciliate, it has been shown that hydrodynamic interactions alone can lead the system to…

流体动力学 · 物理学 2016-03-23 Babak Nasouri , Gwynn J. Elfring

Large groups of active cilia collectively beat in a fluid medium as metachronal waves, essential for some microorganisms motility and for flow generation in mucociliary clearance. Several models can predict the emergence of metachronal…

软凝聚态物质 · 物理学 2024-05-08 Supravat Dey , Gladys Massiera , Estelle Pitard

Cells or bacteria carrying cilia on their surface show many striking features : alignment of cilia in an array, two-phase asymmetric beating for each cilium, coordination between cilia and existence of metachronal waves with a constant…

生物物理 · 物理学 2009-11-11 Boris Guirao , Jean-François Joanny

The dynamics and motion of multi-ciliated microswimmers with a spherical body and a small number N (with 5 < N < 60) of cilia with length comparable to the body radius, is investigated by mesoscale hydrodynamics simulations. A metachronal…

软凝聚态物质 · 物理学 2024-06-03 Sebastian Rode , Jens Elgeti , Gerhard Gompper

Motile cilia are slender, hair-like cellular appendages that spontaneously oscillate under the action of internal molecular motors and are typically found in dense arrays. These active filaments coordinate their beating to generate…

软凝聚态物质 · 物理学 2022-01-28 Brato Chakrabarti , Sebastian Fürthauer , Michael J. Shelley

Organisms use hair-like cilia that beat in a metachronal fashion to actively transport fluid and suspended particles. Metachronal motion emerges due to a phase difference between beating cycles of neighboring cilia and appears as traveling…

流体动力学 · 物理学 2018-06-13 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

Motile cilia beat in an asymmetric fashion in order to propel the surrounding fluid. When many cilia are located on a surface, their beating can synchronise such that their phases form metachronal waves. Here, we computationally study a…

软凝聚态物质 · 物理学 2023-09-29 David J. Hickey , Ramin Golestanian , Andrej Vilfan

Carpets of actively bending cilia represent arrays of biological oscillators that can exhibit self-organized metachronal synchronization in the form of traveling waves of cilia phase. This metachronal coordination supposedly enhances fluid…

生物物理 · 物理学 2022-01-11 Anton Solovev , Benjamin M. Friedrich

In this work we study the effect of metachronal waves on the flow created by magnetically-driven plate-like artificial cilia in microchannels using numerical simulations. The simulations are performed using a coupled magneto-mechanical…

流体动力学 · 物理学 2015-05-30 Syed Khaderi , Jaap den Toonder , Patrick Onck

Cilia and flagella in biological systems often show large scale cooperative behaviors such as the synchronization of their beats in "metachronal waves". These are beautiful examples of emergent dynamics in biology, and are essential for…

软凝聚态物质 · 物理学 2016-04-20 Nicolas Bruot , Pietro Cicuta

We examine the hydrodynamic performance of two cilia beating patterns reconstructed from experimental data. In their respective natural systems, the two beating patterns correspond to: (A) pumping-specialized cilia, and (B)…

流体动力学 · 物理学 2015-06-19 Hanliang Guo , Janna Nawroth , Yang Ding , Eva Kanso

By taking into account the hydrodynamic interactions in a one dimensional array of model cilia attached to a no-slip cylinderical surface, we investigate their synchronized motion. We show, how does the emergence of metachronal waves depend…

生物物理 · 物理学 2017-05-31 Aref Ghorbani , Ali Najafi

Ciliated tissues such as in the mammalian lungs, brains, and reproductive tracts, are specialized to pump fluid. They generate flows by the collective activity of hundreds of thousands of individual cilia that beat in a striking metachronal…

软凝聚态物质 · 物理学 2022-11-30 Anup Kanale , Feng Ling , Hanliang Guo , Sebastian Fuerthauer , Eva Kanso

We employ a model system, called rowers, as a generic physical framework to define the problem of the coordinated motion of cilia (the metachronal wave) as a far from equilibrium process. Rowers are active (two-state) oscillators…

生物物理 · 物理学 2013-05-29 M. Cosentino Lagomarsino , P. Jona , B. Bassetti

In nature, metachronal coordination is an efficient strategy for fluid pumping and self-propulsion. Yet, mimetic systems for this type of organization are scarce. Recently, metachronal motion was observed in a bead-based magnetocapillary…

We calculate the hydrodynamic flow field generated far from a cilium which is attached to a surface and beats periodically. In the case of two beating cilia, hydrodynamic interactions can lead to synchronization of the cilia, which are…

生物物理 · 物理学 2007-05-23 Andrej Vilfan , Frank Julicher

A variety of swimming microorganisms, called ciliates, exploit the bending of a large number of small and densely-packed organelles, termed cilia, in order to propel themselves in a viscous fluid. We consider a spherical envelope model for…

流体动力学 · 物理学 2011-08-30 Sebastien Michelin , Eric Lauga

We introduce a measure for energetic efficiency of biological cilia acting individually or collectively and numerically determine the optimal beating patterns according to this criterion. Maximizing the efficiency of a single cilium leads…

生物物理 · 物理学 2011-09-21 Natan Osterman , Andrej Vilfan

Filaments on the surface of a microorganism such as Paramecium or Ophalina beat highly synchronized and form so-called metachronal waves that travel along the surfaces. In order to study under what principal conditions these waves form, we…

生物物理 · 物理学 2010-12-16 Christopher Wollin , Holger Stark
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