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Uncertainty estimation is critical for cost-sensitive deep-learning applications (i.e. disease diagnosis). It is very challenging partly due to the inaccessibility of uncertainty groundtruth in most datasets. Previous works proposed to…

机器学习 · 计算机科学 2021-10-18 Bolian Li , Zige Zheng , Changqing Zhang

The objective of this work is to quantify the uncertainty in probability of failure estimates resulting from incomplete knowledge of the probability distributions for the input random variables. We propose a framework that couples the…

统计方法学 · 统计学 2021-10-26 Dimitris G. Giovanis , Michael Shields

We introduce inherent measures for effective quality control of brain segmentation based on a Bayesian fully convolutional neural network, using model uncertainty. Monte Carlo samples from the posterior distribution are efficiently…

计算机视觉与模式识别 · 计算机科学 2018-06-11 Abhijit Guha Roy , Sailesh Conjeti , Nassir Navab , Christian Wachinger

Optimization is widely used in statistics, and often efficiently delivers point estimates on useful spaces involving structural constraints or combinatorial structure. To quantify uncertainty, Gibbs posterior exponentiates the negative loss…

统计方法学 · 统计学 2025-07-23 Cheng Zeng , Eleni Dilma , Jason Xu , Leo L Duan

Network models provide a powerful framework for analysing single-cell count data, facilitating the characterisation of cellular identities, disease mechanisms, and developmental trajectories. However, uncertainty modeling in unsupervised…

基因组学 · 定量生物学 2026-04-27 Shanshan Ren , Thomas E. Bartlett , Lina Gerontogianni , Swati Chandna

Accurately knowing uncertainties in appearance-based gaze tracking is critical for ensuring reliable downstream applications. Due to the lack of individual uncertainty labels, current uncertainty-aware approaches adopt probabilistic models…

计算机视觉与模式识别 · 计算机科学 2026-03-13 Qiaojie Zheng , Jiucai Zhang , Xiaoli Zhang

The generalization performance of deep learning models for medical image analysis often decreases on images collected with different devices for data acquisition, device settings, or patient population. A better understanding of the…

计算机视觉与模式识别 · 计算机科学 2023-07-20 Aleksandar Vakanski , Min Xian

We develop a generative model-based approach to Bayesian inverse problems, such as image reconstruction from noisy and incomplete images. Our framework addresses two common challenges of Bayesian reconstructions: 1) It makes use of complex,…

机器学习 · 统计学 2019-10-24 Vanessa Böhm , François Lanusse , Uroš Seljak

Rigorous statistical methods, including parameter estimation with accompanying uncertainties, underpin the validity of scientific discovery, especially in the natural sciences. With increasingly complex data models such as deep learning…

机器学习 · 计算机科学 2026-02-18 Aurora Grefsrud , Nello Blaser , Trygve Buanes

We consider the problem of estimating fold-changes in the expected value of a multivariate outcome observed with unknown sample-specific and category-specific perturbations. This challenge arises in high-throughput sequencing studies of the…

统计方法学 · 统计学 2026-04-24 David S Clausen , Sarah Teichman , Amy D Willis

3D microscopy is key in the investigation of diverse biological systems, and the ever increasing availability of large datasets demands automatic cell identification methods that not only are accurate, but also can imply the uncertainty in…

计算机视觉与模式识别 · 计算机科学 2021-02-24 Alvaro Gomariz , Tiziano Portenier , César Nombela-Arrieta , Orcun Goksel

We propose a novel approach to Bayesian analysis that is provably robust to outliers in the data and often has computational advantages over standard methods. Our technique is based on splitting the data into non-overlapping subgroups,…

统计理论 · 数学 2016-06-03 Stanislav Minsker , Sanvesh Srivastava , Lizhen Lin , David B. Dunson

Deep learning based methods for automatic organ segmentation have shown promise in aiding diagnosis and treatment planning. However, quantifying and understanding the uncertainty associated with model predictions is crucial in critical…

图像与视频处理 · 电气工程与系统科学 2023-08-16 Jadie Adams , Shireen Y. Elhabian

Progress in probabilistic generative models has accelerated, developing richer models with neural architectures, implicit densities, and with scalable algorithms for their Bayesian inference. However, there has been limited progress in…

机器学习 · 统计学 2017-10-31 Dustin Tran , David M. Blei

Bayesian deep learning counts on the quality of posterior distribution estimation. However, the posterior of deep neural networks is highly multi-modal in nature, with local modes exhibiting varying generalization performance. Given a…

机器学习 · 计算机科学 2024-03-27 Bolian Li , Ruqi Zhang

Over the past decades, computer-aided diagnosis tools for breast cancer have been developed to enhance screening procedures, yet their clinical adoption remains challenged by data variability and inherent biases. Although foundation models…

计算机视觉与模式识别 · 计算机科学 2025-05-20 Elodie Germani , Ilayda Selin Türk , Fatima Zeineddine , Charbel Mourad , Shadi Albarqouni

When random effects are correlated with sample design variables, the usual approach of employing individual survey weights (constructed to be inversely proportional to the unit survey inclusion probabilities) to form a pseudo-likelihood no…

统计方法学 · 统计学 2021-08-26 Terrance D. Savitsky , Matthew R. Williams

Modern neural networks tend to be overconfident on unseen, noisy or incorrectly labelled data and do not produce meaningful uncertainty measures. Bayesian deep learning aims to address this shortcoming with variational approximations (such…

机器学习 · 统计学 2018-05-28 Nick Pawlowski , Andrew Brock , Matthew C. H. Lee , Martin Rajchl , Ben Glocker

Validation metrics are a key prerequisite for the reliable tracking of scientific progress and for deciding on the potential clinical translation of methods. While recent initiatives aim to develop comprehensive theoretical frameworks for…

Despite the promise of Convolutional neural network (CNN) based classification models for histopathological images, it is infeasible to quantify its uncertainties. Moreover, CNNs may suffer from overfitting when the data is biased. We show…

计算机视觉与模式识别 · 计算机科学 2021-11-09 Ponkrshnan Thiagarajan , Pushkar Khairnar , Susanta Ghosh