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Optimization plays an important role in tackling public health problems. Animal instincts can be used effectively to solve complex public health management issues by providing optimal or approximately optimal solutions to complicated…

神经与进化计算 · 计算机科学 2025-03-24 Eliuvish Cuicizion , Haowen Xu , Weng Kee Wong

Comparing mathematical models offers a means to evaluate competing scientific theories. However, exact methods of model calibration are not applicable to many probabilistic models which simulate high-dimensional spatio-temporal data.…

定量方法 · 定量生物学 2026-01-13 Robert A McDonald , Helen M Byrne , Heather A Harrington , Thomas Thorne , Bernadette J Stolz

Bio-inspired optimization (including Evolutionary Computation and Swarm Intelligence) is a growing research topic with many competitive bio-inspired algorithms being proposed every year. In such an active area, preparing a successful…

神经与进化计算 · 计算机科学 2024-10-07 Antonio LaTorre , Daniel Molina , Eneko Osaba , Javier Del Ser , Francisco Herrera

The human nervous system utilizes synaptic plasticity to solve optimization problems. Previous studies have tried to add the plasticity factor to the training process of artificial neural networks, but most of those models require complex…

神经与进化计算 · 计算机科学 2022-04-13 Amir Valizadeh

Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…

医学物理 · 物理学 2023-12-05 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

Increasing nature-inspired metaheuristic algorithms are applied to solving the real-world optimization problems, as they have some advantages over the classical methods of numerical optimization. This paper has proposed a new…

神经与进化计算 · 计算机科学 2017-08-10 Bing Zeng , Liang Gao , Xinyu Li

Recently, there has been a resurgence of interest in rigorous algorithms for the inference of cancer progression from genomic data. The motivations are manifold: (i) growing NGS and single cell data from cancer patients, (ii) need for novel…

机器学习 · 计算机科学 2016-02-25 Daniele Ramazzotti

This letter considers optimizing user association in a heterogeneous network via utility maximization, which is a combinatorial optimization problem due to integer constraints. Different from existing solutions based on convex optimization,…

信息论 · 计算机科学 2018-06-12 Xietian Huang , Wei Xu , Guo Xie , Shi Jin , Xiaohu You

Machine Learning algorithms have been extensively researched throughout the last decade, leading to unprecedented advances in a broad range of applications, such as image classification and reconstruction, object recognition, and text…

人工智能 · 计算机科学 2022-12-20 Gustavo H. de Rosa , Mateus Roder , João Paulo Papa , Claudio F. G. dos Santos

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

统计方法学 · 统计学 2015-11-25 Stéphane Guerrier , Nabil Mili , Roberto Molinari , Samuel Orso , Marco Avella-Medina , Yanyuan Ma

Metaheuristics are stochastic optimization algorithms that mimic natural processes to find optimal solutions to complex problems. The success of metaheuristics largely depends on the ability to effectively explore and exploit the search…

神经与进化计算 · 计算机科学 2024-11-26 Salar Farahmand-Tabar

In the realm of medical science, the pursuit of enhancing treatment efficacy and patient outcomes continues to drive innovation. This study delves into the integration of biomimicry principles within the domain of Radiation Therapy (RT) to…

神经与进化计算 · 计算机科学 2025-01-07 Keshav Kumar K. , NVSL Narasimham

Proton therapy is a modality in fast development. Characterized by a maximum dose deposition at the end of the proton trajectory followed by a sharp fall-off, proton beams can deliver a highly conformal dose to the tumor while sparing…

医学物理 · 物理学 2022-05-18 François Smekens , Nicolas Freud , Bruno Sixou , Guillaume Beslon , Jean M Létang

Bio inspiration is a branch of artificial simulation science that shows pervasive contributions to variety of engineering fields such as automate pattern recognition, systematic fault detection and applied optimization. In this paper, a new…

神经与进化计算 · 计算机科学 2013-12-17 Ahmad Mozaffari , Alireza Fathi

Theoretical and computational tools that can be used in the clinic to predict neoplastic progression and propose individualized optimal treatment strategies to control cancer growth is desired. To develop such a predictive model, one must…

细胞行为 · 定量生物学 2015-05-20 Salvatore Torquato

Understanding how microenvironmental heterogeneity influences tumor progression is essential for advancing both cancer biology and therapeutic strategies. In this study, we develop a cellular automata (CA) model to simulate tumor growth…

细胞行为 · 定量生物学 2026-01-26 Yue Deng , Mingjing Li , Jinzhi Lei

Swarm intelligence and bio-inspired algorithms form a hot topic in the developments of new algorithms inspired by nature. These nature-inspired metaheuristic algorithms can be based on swarm intelligence, biological systems, physical and…

神经与进化计算 · 计算机科学 2013-07-17 Iztok Fister , Xin-She Yang , Iztok Fister , Janez Brest , Dušan Fister

This work focuses on the optimization of the training trajectory orientation using a robot as an advanced exercise machine (AEM) and muscle activations as biofeedback. Muscle recruitment patterns depend on trajectory parameters of the AEMs…

机器人学 · 计算机科学 2021-04-26 Humberto De las Casas , Nicholas Chambers , Hanz Richter , Kenneth Sparks

Based on recent experiments with time-lapse fluorescent imaging, we propose a cellular automaton model for the dynamics of vascular endothelial cells (ECs) in angiogenic morphogenesis. The model successfully reproduces cell mixing behavior,…

元胞自动机与格子气 · 物理学 2015-07-22 Keisuke Matsuya , Hiroki Kurihara , Tetsuji Tokihiro

Angiogenesis is the formation of new blood vessels from pre-existing ones in response to chemical signals secreted by, for example, a wound or a tumour. In this paper, we propose a mesoscopic lattice-based model of angiogenesis, in which…

组织与器官 · 定量生物学 2016-03-02 Fabian Spill , Pilar Guerrero , Tomas Alarcon , Philip K. Maini , Helen M. Byrne