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In observational studies, treatment may be adapted to covariates at several times without a fixed protocol, in continuous time. Treatment influences covariates, which influence treatment, which influences covariates, and so on. Then even…

统计理论 · 数学 2015-09-02 Judith J. Lok

Causal inference with observational data can be performed under an assumption of no unobserved confounders (unconfoundedness assumption). There is, however, seldom clear subject-matter or empirical evidence for such an assumption. We…

统计方法学 · 统计学 2023-11-13 Minna Genbäck , Xavier de Luna

Two problems that arise in making causal inferences for non-mortality outcomes such as bronchopulmonary dysplasia (BPD) are unmeasured confounding and censoring by death, i.e., the outcome is only observed when subjects survive. In…

统计方法学 · 统计学 2018-02-20 Kwonsang Lee , Scott A. Lorch , Dylan S. Small

When drawing causal inference from observational data, there is always concern about unmeasured confounding. One way to tackle this is to conduct a sensitivity analysis. One widely-used sensitivity analysis framework hypothesizes the…

统计方法学 · 统计学 2022-06-22 Bo Zhang , Eric J. Tchetgen Tchetgen

Recently, interest has grown in the use of proxy variables of unobserved confounding for inferring the causal effect in the presence of unmeasured confounders from observational data. One difficulty inhibiting the practical use is finding…

机器学习 · 计算机科学 2024-05-28 Feng Xie , Zhengming Chen , Shanshan Luo , Wang Miao , Ruichu Cai , Zhi Geng

When studying the causal effect of $x$ on $y$, researchers may conduct regression and report a confidence interval for the slope coefficient $\beta_{x}$. This common confidence interval provides an assessment of uncertainty from sampling…

统计方法学 · 统计学 2019-08-26 Brian Knaeble , Braxton Osting , Mark Abramson

In causal inference, treatment effects are typically estimated under the ignorability, or unconfoundedness, assumption, which is often unrealistic in observational data. By relaxing this assumption and conducting a sensitivity analysis, we…

We examine interval estimation of the effect of a treatment T on an outcome Y given the existence of an unobserved confounder U. Using H\"older's inequality, we derive a set of bounds on the confounding bias |E[Y|T=t]-E[Y|do(T=t)]| based on…

机器学习 · 计算机科学 2021-07-14 Serge Assaad , Shuxi Zeng , Henry Pfister , Fan Li , Lawrence Carin

Across domains such as medicine, employment, and criminal justice, predictive models often target labels that imperfectly reflect the outcomes of interest to experts and policymakers. For example, clinical risk assessments deployed to…

机器学习 · 计算机科学 2023-05-19 Luke Guerdan , Amanda Coston , Kenneth Holstein , Zhiwei Steven Wu

We propose a model-free framework for sensitivity analysis of individual treatment effects (ITEs), building upon ideas from conformal inference. For any unit, our procedure reports the $\Gamma$-value, a number which quantifies the minimum…

统计方法学 · 统计学 2022-04-26 Ying Jin , Zhimei Ren , Emmanuel J. Candès

Proxy variables are commonly used in causal inference when unmeasured confounding exists. While most existing proximal methods assume a unidirectional causal relationship between two primary variables, many social and biological systems…

统计方法学 · 统计学 2025-07-21 Jiaqi Min , Xueyue Zhang , Shanshan Luo

Counterfactual prediction is about predicting outcome of the unobserved situation from the data. For example, given patient is on drug A, what would be the outcome if she switch to drug B. Most of existing works focus on modeling…

机器学习 · 计算机科学 2020-10-29 Yanbo Xu , Cao Xiao , Jimeng Sun

Balanced representation learning methods have been applied successfully to counterfactual inference from observational data. However, approaches that account for survival outcomes are relatively limited. Survival data are frequently…

The assumption of no unmeasured confounders is a critical but unverifiable assumption required for causal inference yet quantitative sensitivity analyses to assess robustness of real-world evidence remains underutilized. The lack of use is…

Causal inference from observational data requires assumptions. These assumptions range from measuring confounders to identifying instruments. Traditionally, causal inference assumptions have focused on estimation of effects for a single…

机器学习 · 统计学 2019-03-04 Rajesh Ranganath , Adler Perotte

Unobserved confounding is one of the main challenges when estimating causal effects. We propose a causal reduction method that, given a causal model, replaces an arbitrary number of possibly high-dimensional latent confounders with a single…

机器学习 · 统计学 2023-02-24 Maximilian Ilse , Patrick Forré , Max Welling , Joris M. Mooij

We study policy evaluation of offline contextual bandits subject to unobserved confounders. Sensitivity analysis methods are commonly used to estimate the policy value under the worst-case confounding over a given uncertainty set. However,…

机器学习 · 统计学 2026-01-13 Kei Ishikawa , Niao He , Takafumi Kanamori

In observational studies, contingency tables provide a simple and intuitive approach to study associations between categorical variables. However, any test of association in contingency tables may be biased due to unmeasured confounders.…

统计方法学 · 统计学 2025-10-10 Elaine K. Chiu , Hyunseung Kang

In this paper, we consider the extent of the biases that may arise when an unmeasured confounder is omitted from a structural equation model (SEM) and we propose sensitivity analysis techniques to correct for such biases. We give an…

统计方法学 · 统计学 2021-03-11 Adam J. Sullivan , Tyler J. VanderWeele

Survey weighting allows researchers to account for bias in survey samples, due to unit nonresponse or convenience sampling, using measured demographic covariates. Unfortunately, in practice, it is impossible to know whether the estimated…

统计方法学 · 统计学 2023-03-07 Erin Hartman , Melody Huang