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Unsupervised anomaly detection (UAD) based on deep generative modelling has been increasingly explored for identifying pathological brain abnormalities without requiring voxel-level annotations. By learning the distribution of healthy…

计算机视觉与模式识别 · 计算机科学 2026-03-10 Youwan Mahé , Elise Bannier , Stéphanie Leplaideur , Elisa Fromont , Francesca Galassi

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

图像与视频处理 · 电气工程与系统科学 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

With the development of medical imaging technology, medical images have become an important basis for doctors to diagnose patients. The brain structure in the collected data is complicated, thence, doctors are required to spend plentiful…

图像与视频处理 · 电气工程与系统科学 2020-07-10 Nan Wang , Chengwei Chen , Yuan Xie , Lizhuang Ma

Magnetic resonance imaging (MRI) is the gold standard for brain imaging. Deep learning (DL) algorithms have been proposed to aid in the diagnosis of diseases such as Alzheimer's disease (AD) from MRI scans. However, DL algorithms can suffer…

计算机视觉与模式识别 · 计算机科学 2025-09-12 Akshit Achara , Esther Puyol Anton , Alexander Hammers , Andrew P. King

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

图像与视频处理 · 电气工程与系统科学 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

Congenital malformations of the brain are among the most common fetal abnormalities that impact fetal development. Previous anomaly detection methods on ultrasound images are based on supervised learning, rely on manual annotations, and…

In medical imaging, anomaly detection is a vital element of healthcare diagnostics, especially for neurological conditions which can be life-threatening. Conventional deterministic methods often fall short when it comes to capturing the…

机器学习 · 计算机科学 2025-04-23 Dip Roy

Unsupervised anomaly detection is a popular approach for the analysis of neuroimaging data as it allows to identify a wide variety of anomalies from unlabelled data. It relies on building a subject-specific model of healthy appearance to…

图像与视频处理 · 电气工程与系统科学 2023-11-22 Maëlys Solal , Ravi Hassanaly , Ninon Burgos

Current unsupervised anomaly localization approaches rely on generative models to learn the distribution of normal images, which is later used to identify potential anomalous regions derived from errors on the reconstructed images. However,…

图像与视频处理 · 电气工程与系统科学 2022-07-13 Julio Silva-Rodríguez , Valery Naranjo , Jose Dolz

Current unsupervised anomaly localization approaches rely on generative models to learn the distribution of normal images, which is later used to identify potential anomalous regions derived from errors on the reconstructed images. However,…

图像与视频处理 · 电气工程与系统科学 2021-10-29 Julio Silva-Rodríguez , Valery Naranjo , Jose Dolz

Anomaly detection plays a crucial role in various real-world applications, including healthcare and finance systems. Owing to the limited number of anomaly labels in these complex systems, unsupervised anomaly detection methods have…

机器学习 · 计算机科学 2023-10-10 Zongyuan Huang , Baohua Zhang , Guoqiang Hu , Longyuan Li , Yanyan Xu , Yaohui Jin

The present study performs a comprehensive fairness analysis of machine learning (ML) models for the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) from MRI-derived neuroimaging features. Biases associated with…

机器学习 · 计算机科学 2025-05-30 Maria Eleftheria Vlontzou , Maria Athanasiou , Christos Davatzikos , Konstantina S. Nikita

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

图像与视频处理 · 电气工程与系统科学 2025-06-13 Ana Lawry Aguila , Peirong Liu , Oula Puonti , Juan Eugenio Iglesias

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

图像与视频处理 · 电气工程与系统科学 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Detection of various lesions in brain MRI is clinically critical, but challenging due to the diversity of lesions and variability in imaging conditions. Current unsupervised learning methods detect anomalies mainly through reconstructing…

计算机视觉与模式识别 · 计算机科学 2025-12-29 Tao Yang , Xiuying Wang , Hao Liu , Guanzhong Gong , Lian-Ming Wu , Yu-Ping Wang , Lisheng Wang

In this work, we tackle the problem of Semi-Supervised Anomaly Segmentation (SAS) in Magnetic Resonance Images (MRI) of the brain, which is the task of automatically identifying pathologies in brain images. Our work challenges the…

图像与视频处理 · 电气工程与系统科学 2023-09-26 Felix Meissen , Georgios Kaissis , Daniel Rueckert

Unsupervised anomaly detection (UAD) plays a crucial role in neuroimaging for identifying deviations from healthy subject data and thus facilitating the diagnosis of neurological disorders. In this work, we focus on Bayesian flow networks…

计算机视觉与模式识别 · 计算机科学 2025-10-21 Hugues Roy , Reuben Dorent , Ninon Burgos

Anomaly detection presents a unique challenge in machine learning, due to the scarcity of labeled anomaly data. Recent work attempts to mitigate such problems by augmenting training of deep anomaly detection models with additional labeled…

机器学习 · 计算机科学 2021-05-18 Ziyu Ye , Yuxin Chen , Haitao Zheng

The detection of lesions in magnetic resonance imaging (MRI)-scans of human brains remains challenging, time-consuming and error-prone. Recently, unsupervised anomaly detection (UAD) methods have shown promising results for this task. These…

图像与视频处理 · 电气工程与系统科学 2022-04-13 Finn Behrendt , Marcel Bengs , Frederik Rogge , Julia Krüger , Roland Opfer , Alexander Schlaefer

Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD)…

图像与视频处理 · 电气工程与系统科学 2022-02-01 Marcel Bengs , Finn Behrendt , Max-Heinrich Laves , Julia Krüger , Roland Opfer , Alexander Schlaefer