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The segmentation of endoscopic images plays a vital role in computer-aided diagnosis and treatment. The advancements in deep learning have led to the employment of numerous models for endoscopic tumor segmentation, achieving promising…

计算机视觉与模式识别 · 计算机科学 2025-02-03 Lingcong Cai , Yun Li , Xiaomao Fan , Kaixuan Song , Ruxin Wang , Wenbin Lei

Vision-and-language pretraining (VLP) in the medical field utilizes contrastive learning on image-text pairs to achieve effective transfer across tasks. Yet, current VLP approaches with the masked modeling strategy face two challenges when…

计算机视觉与模式识别 · 计算机科学 2025-04-17 Biao Wu , Yutong Xie , Zeyu Zhang , Minh Hieu Phan , Qi Chen , Ling Chen , Qi Wu

Semi-supervised learning has demonstrated great potential in medical image segmentation by utilizing knowledge from unlabeled data. However, most existing approaches do not explicitly capture high-level semantic relations between distant…

计算机视觉与模式识别 · 计算机科学 2023-12-07 Qianying Liu , Xiao Gu , Paul Henderson , Fani Deligianni

In ordinal classification, misclassifying neighboring ranks is common, yet the consequences of these errors are not the same. For example, misclassifying benign tumor categories is less consequential, compared to an error at the…

计算机视觉与模式识别 · 计算机科学 2026-01-13 Dileepa Pitawela , Gustavo Carneiro , Hsiang-Ting Chen

Contrastive Language-Image Pretraining (CLIP) has achieved remarkable success, leading to rapid advancements in multimodal studies. However, CLIP faces a notable challenge in terms of inefficient data utilization. It relies on a single…

计算机视觉与模式识别 · 计算机科学 2024-06-05 Yu Zhang , Qi Zhang , Zixuan Gong , Yiwei Shi , Yepeng Liu , Duoqian Miao , Yang Liu , Ke Liu , Kun Yi , Wei Fan , Liang Hu , Changwei Wang

Pan-omics, pan-cancer analysis has advanced our understanding of the molecular heterogeneity of cancer, expanding what was known from single-cancer or single-omics studies. However, pan-cancer, pan-omics analyses have been limited in their…

应用统计 · 统计学 2021-03-02 Sarah Samorodnitsky , Katherine A. Hoadley , Eric F. Lock

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

计算机视觉与模式识别 · 计算机科学 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

Contrastive learning (CL) has been successful as a powerful representation learning method. In this work we propose CLIM: Contrastive Learning with mutual Information Maximization, to explore the potential of CL on cross-domain sentiment…

计算与语言 · 计算机科学 2020-11-13 Tian Li , Xiang Chen , Shanghang Zhang , Zhen Dong , Kurt Keutzer

Virtual screening, which identifies potential drugs from vast compound databases to bind with a particular protein pocket, is a critical step in AI-assisted drug discovery. Traditional docking methods are highly time-consuming, and can only…

机器学习 · 计算机科学 2023-10-11 Bowen Gao , Bo Qiang , Haichuan Tan , Minsi Ren , Yinjun Jia , Minsi Lu , Jingjing Liu , Weiying Ma , Yanyan Lan

Cancer remains one of the most challenging diseases to treat in the medical field. Machine learning has enabled in-depth analysis of rich multi-omics profiles and medical imaging for cancer diagnosis and prognosis. Despite these…

机器学习 · 计算机科学 2024-01-15 Lingchao Mao , Hairong Wang , Leland S. Hu , Nhan L Tran , Peter D Canoll , Kristin R Swanson , Jing Li

Although fusion of information from multiple views of mammograms plays an important role to increase accuracy of breast cancer detection, developing multi-view mammograms-based computer-aided diagnosis (CAD) schemes still faces challenges…

计算机视觉与模式识别 · 计算机科学 2024-04-25 Xuxin Chen , Yuheng Li , Mingzhe Hu , Ella Salari , Xiaoqian Chen , Richard L. J. Qiu , Bin Zheng , Xiaofeng Yang

Cancer evolves continuously over time through a complex interplay of genetic, epigenetic, microenvironmental, and phenotypic changes. This dynamic behavior drives uncontrolled cell growth, metastasis, immune evasion, and therapy resistance,…

定量方法 · 定量生物学 2025-07-08 Luoting Zhuang , Stephen H. Park , Steven J. Skates , Ashley E. Prosper , Denise R. Aberle , William Hsu

Accurately predicting drug responses to cancer is an important problem hindering oncologists' efforts to find the most effective drugs to treat cancer, which is a core goal in precision medicine. The scientific community has focused on…

机器学习 · 计算机科学 2016-12-06 Turki Turki , Zhi Wei

Advances in high-throughput technologies have originated an ever-increasing availability of omics datasets. The integration of multiple heterogeneous data sources is currently an issue for biology and bioinformatics. Multiple kernel…

With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

定量方法 · 定量生物学 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

图像与视频处理 · 电气工程与系统科学 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

Brain tumor is a common and fatal form of cancer which affects both adults and children. The classification of brain tumors into different types is hence a crucial task, as it greatly influences the treatment that physicians will prescribe.…

计算机视觉与模式识别 · 计算机科学 2021-08-10 Tian Yu Liu , Jiashi Feng

Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…

计算机视觉与模式识别 · 计算机科学 2023-09-07 Ting Jin , Xingran Xie , Renjie Wan , Qingli Li , Yan Wang

Multimodal deep learning holds promise for improving clinical prediction by integrating diverse patient data, including text, imaging, time-series, and structured demographics. Contrastive learning facilitates this integration by producing…

机器学习 · 计算机科学 2025-07-08 Michal Golovanevsky , Pranav Mahableshwarkar , Carsten Eickhoff , Ritambhara Singh

We introduce MOSAIC (Masked Objective with Selective Adaptation for In-domain Contrastive learning), a multi-stage framework for domain adaptation of text embedding models that incorporates joint domain-specific masked supervision. Our…

计算与语言 · 计算机科学 2026-01-30 Vera Pavlova , Mohammed Makhlouf