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Delineation of cancerous regions in gigapixel whole slide images (WSIs) is a crucial diagnostic procedure in digital pathology. This process is time-consuming because of the large search space in the gigapixel WSIs, causing chances of…

图像与视频处理 · 电气工程与系统科学 2020-07-21 Hsien-Tzu Cheng , Chun-Fu Yeh , Po-Chen Kuo , Andy Wei , Keng-Chi Liu , Mong-Chi Ko , Kuan-Hua Chao , Yu-Ching Peng , Tyng-Luh Liu

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

Federated Unsupervised Learning (FUL) aims to learn expressive representations in federated and self-supervised settings. The quality of representations learned in FUL is usually determined by uniformity, a measure of how uniformly…

机器学习 · 计算机科学 2025-08-05 Hung-Chieh Fang , Hsuan-Tien Lin , Irwin King , Yifei Zhang

Classification of gigapixel Whole Slide Images (WSIs) is an important prediction task in the emerging area of computational pathology. There has been a surge of research in deep learning models for WSI classification with clinical…

计算机视觉与模式识别 · 计算机科学 2023-05-04 Sajid Javed , Arif Mahmood , Talha Qaiser , Naoufel Werghi , Nasir Rajpoot

Labelling tissue components in histology whole slide images (WSIs) is prohibitively labour-intensive: a single slide may contain tens of thousands of structures--cells, nuclei, and other morphologically distinct objects--each requiring…

定量方法 · 定量生物学 2026-04-13 Muhammad Haseeb Ahmad , Sharmila Rajendran , Damion Young , Jon Mason

Recent work has shown that augmenting environments with language descriptions improves policy learning. However, for environments with complex language abstractions, learning how to ground language to observations is difficult due to…

机器学习 · 计算机科学 2022-10-04 Victor Zhong , Jesse Mu , Luke Zettlemoyer , Edward Grefenstette , Tim Rocktäschel

Computational pathology has advanced rapidly in recent years, driven by domain-specific image encoders and growing interest in using vision-language models to answer natural-language questions about diseases. Yet, the core problem behind…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Wentao Huang , Weimin Lyu , Peiliang Lou , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Wenchao Han , Ruifeng Guo , Jiawei Zhou , Chao Chen , Chen Wang

This work introduces a novel knowledge distillation framework for classification tasks where information on existing subclasses is available and taken into consideration. In classification tasks with a small number of classes or binary…

机器学习 · 计算机科学 2022-07-06 Ahmad Sajedi , Konstantinos N. Plataniotis

Sparse neural systems are gaining traction for efficient continual learning due to their modularity and low interference. Architectures such as Sparse Distributed Memory Multi-Layer Perceptrons (SDMLP) construct task-specific subnetworks…

机器学习 · 计算机科学 2025-12-18 Huiyan Xue , Xuming Ran , Yaxin Li , Qi Xu , Enhui Li , Yi Xu , Qiang Zhang

Standard Knowledge Distillation (KD) compresses Large Language Models (LLMs) by optimizing final outputs, yet it typically treats the teacher's intermediate layer's thought process as a black box. While feature-based distillation attempts…

计算与语言 · 计算机科学 2026-02-17 Manish Dhakal , Uthman Jinadu , Anjila Budathoki , Rajshekhar Sunderraman , Yi Ding

Knowledge distillation (KD) aims to transfer knowledge from a large teacher model to a smaller student model. Previous work applying KD in the field of large language models (LLMs) typically focused on the post-training phase, where the…

计算与语言 · 计算机科学 2024-10-22 Hao Peng , Xin Lv , Yushi Bai , Zijun Yao , Jiajie Zhang , Lei Hou , Juanzi Li

Recent attention has been devoted to the pursuit of learning semantic segmentation models exclusively from image tags, a paradigm known as image-level Weakly Supervised Semantic Segmentation (WSSS). Existing attempts adopt the Class…

计算机视觉与模式识别 · 计算机科学 2024-08-06 Ye Du , Zehua Fu , Qingjie Liu

Multi-modal learning adeptly integrates visual and textual data, but its application to histopathology image and text analysis remains challenging, particularly with large, high-resolution images like gigapixel Whole Slide Images (WSIs).…

计算机视觉与模式识别 · 计算机科学 2024-05-29 Quan Liu , Ruining Deng , Can Cui , Tianyuan Yao , Vishwesh Nath , Yucheng Tang , Yuankai Huo

Supervised deep learning methods have achieved considerable success in medical image analysis, owing to the availability of large-scale and well-annotated datasets. However, creating such datasets for whole slide images (WSIs) in…

计算机视觉与模式识别 · 计算机科学 2024-06-10 Hao Wang , Euijoon Ahn , Jinman Kim

On-policy self-distillation (SD) improves LLM reasoning by using teacher-side privileged information (PI) to turn sparse verifier outcomes into dense token-level supervision. Existing methods usually assume trusted PI, such as reference…

计算与语言 · 计算机科学 2026-05-28 Jiazhen Huang , Xiao Chen , Xiao Luo , Yong Dai , Senkang Hu , Yuzhi Zhao

Whole slide imaging (WSI) refers to the digitization of a tissue specimen which enables pathologists to explore high-resolution images on a monitor rather than through a microscope. The formation of tissue folds occur during tissue…

图像与视频处理 · 电气工程与系统科学 2019-03-19 Morteza Babaie , H. R. Tizhoosh

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

计算机视觉与模式识别 · 计算机科学 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

Knowledge Distillation (KD) has emerged as a promising approach for transferring knowledge from a larger, more complex teacher model to a smaller student model. Traditionally, KD involves training the student to mimic the teacher's output…

机器学习 · 计算机科学 2024-10-03 Noel Loo , Fotis Iliopoulos , Wei Hu , Erik Vee

Multiple Instance Learning (MIL) methods allow for gigapixel Whole-Slide Image (WSI) analysis with only slide-level annotations. Interpretability is crucial for safely deploying such algorithms in high-stakes medical domains. Traditional…

计算机视觉与模式识别 · 计算机科学 2025-01-07 Susu Sun , Leslie Tessier , Frédérique Meeuwsen , Clément Grisi , Dominique van Midden , Geert Litjens , Christian F. Baumgartner