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With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer diagnosis. Limited by the expensive cost of pixel-level…

计算机视觉与模式识别 · 计算机科学 2024-11-19 Jiawen Li , Qiehe Sun , Renao Yan , Yizhi Wang , Yuqiu Fu , Yani Wei , Tian Guan , Huijuan Shi , Yonghonghe He , Anjia Han

Whole slide images~(WSIs) are digitized images of tissues placed in glass slides using advanced scanners. The digital processing of WSIs is challenging as they are gigapixel images and stored in multi-resolution format. A common challenge…

图像与视频处理 · 电气工程与系统科学 2023-10-30 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

计算机视觉与模式识别 · 计算机科学 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu

Digital pathology is revolutionizing the field of pathology by enabling the digitization, storage, and analysis of tissue samples as whole slide images (WSIs). WSIs are gigapixel files that capture the intricate details of tissue samples,…

图像与视频处理 · 电气工程与系统科学 2024-09-10 S. Hemati , Krishna R. Kalari , H. R. Tizhoosh

Enhancing the robustness of deep learning models against adversarial attacks is crucial, especially in critical domains like healthcare where significant financial interests heighten the risk of such attacks. Whole slide images (WSIs) are…

计算机视觉与模式识别 · 计算机科学 2024-03-22 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

Domain generalization in computational histopathology is hindered by heterogeneity in whole slide images (WSIs), caused by variations in tissue preparation, staining, and imaging conditions across institutions. Unlike machine learning…

计算机视觉与模式识别 · 计算机科学 2025-09-03 Hikmat Khan , Syed Farhan Alam Zaidi , Pir Masoom Shah , Kiruthika Balakrishnan , Rabia Khan , Muhammad Waqas , Jia Wu

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

图像与视频处理 · 电气工程与系统科学 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

Whole slide image (WSI) registration is an essential task for analysing the tumour microenvironment (TME) in histopathology. It involves the alignment of spatial information between WSIs of the same section or serial sections of a tissue…

图像与视频处理 · 电气工程与系统科学 2025-02-27 Behnaz Elhaminia , Abdullah Alsalemi , Esha Nasir , Mostafa Jahanifar , Ruqayya Awan , Lawrence S. Young , Nasir M. Rajpoot , Fayyaz Minhas , Shan E Ahmed Raza

Hyperspectral image (HSI) clustering has been a fundamental but challenging task with zero training labels. Currently, some deep graph clustering methods have been successfully explored for HSI due to their outstanding performance in…

计算机视觉与模式识别 · 计算机科学 2025-01-08 Yao Ding , Weijie Kang , Aitao Yang , Zhili Zhang , Junyang Zhao , Jie Feng , Danfeng Hong , Qinhe Zheng

Self-supervised learning (SSL) methods have been increasingly applied to diverse downstream tasks due to their superior generalization capabilities and low annotation costs. However, most existing heterogeneous graph SSL models convert…

机器学习 · 计算机科学 2025-06-10 Di Lin , Wanjing Ren , Xuanbin Li , Rui Zhang

In recent years, histopathological whole slide image (WSI)- based survival analysis has attracted much attention in medical image analysis. In practice, WSIs usually come from different hospitals or laboratories, which can be seen as…

计算机视觉与模式识别 · 计算机科学 2024-11-22 Yuntao Shou , Peiqiang Yan , Xingjian Yuan , Xiangyong Cao , Qian Zhao , Deyu Meng

Generative self-supervised learning (SSL), especially masked autoencoders, has become one of the most exciting learning paradigms and has shown great potential in handling graph data. However, real-world graphs are always heterogeneous,…

机器学习 · 计算机科学 2023-02-13 Yijun Tian , Kaiwen Dong , Chunhui Zhang , Chuxu Zhang , Nitesh V. Chawla

Deep learning is a powerful tool for whole slide image (WSI) analysis. Typically, when performing supervised deep learning, a WSI is divided into small patches, trained and the outcomes are aggregated to estimate disease grade. However,…

计算机视觉与模式识别 · 计算机科学 2022-05-20 Yi Zheng , Rushin H. Gindra , Emily J. Green , Eric J. Burks , Margrit Betke , Jennifer E. Beane , Vijaya B. Kolachalama

Whole Slide Image (WSI) classification is often formulated as a Multiple Instance Learning (MIL) problem. Recently, Vision-Language Models (VLMs) have demonstrated remarkable performance in WSI classification. However, existing methods…

计算机视觉与模式识别 · 计算机科学 2024-04-08 Hao Li , Ying Chen , Yifei Chen , Wenxian Yang , Bowen Ding , Yuchen Han , Liansheng Wang , Rongshan Yu

Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

计算机视觉与模式识别 · 计算机科学 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

Histopathology serves as the gold standard in cancer diagnosis, with clinical reports being vital in interpreting and understanding this process, guiding cancer treatment and patient care. The automation of histopathology report generation…

计算机视觉与模式识别 · 计算机科学 2024-06-19 Zhengrui Guo , Jiabo Ma , Yingxue Xu , Yihui Wang , Liansheng Wang , Hao Chen

Recent years have witnessed the emerging success of graph neural networks (GNNs) for modeling structured data. However, most GNNs are designed for homogeneous graphs, in which all nodes and edges belong to the same types, making them…

机器学习 · 计算机科学 2020-03-04 Ziniu Hu , Yuxiao Dong , Kuansan Wang , Yizhou Sun

The heterogeneity of breast cancer presents considerable challenges for its early detection, prognosis, and treatment selection. Convolutional neural networks often neglect the spatial relationships within histopathological images, which…

计算机视觉与模式识别 · 计算机科学 2023-07-18 Akhila Krishna K , Ravi Kant Gupta , Nikhil Cherian Kurian , Pranav Jeevan , Amit Sethi

In the field of computational histopathology, both whole slide images (WSIs) and diagnostic captions provide valuable insights for making diagnostic decisions. However, aligning WSIs with diagnostic captions presents a significant…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Qifeng Zhou , Wenliang Zhong , Yuzhi Guo , Michael Xiao , Hehuan Ma , Junzhou Huang