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In the following short article we adapt a new and popular machine learning model for inference on medical data sets. Our method is based on the Variational AutoEncoder (VAE) framework that we adapt to survival analysis on small data sets…

机器学习 · 统计学 2018-12-06 Cédric Beaulac , Jeffrey S. Rosenthal , David Hodgson

The claims data, containing medical codes, services information, and incurred expenditure, can be a good resource for estimating an individual's health condition and medical risk level. In this study, we developed Transformer-based…

机器学习 · 计算机科学 2021-06-25 Xianlong Zeng , Simon Lin , Chang Liu

The integrative analysis of histopathological images and genomic data has received increasing attention for survival prediction of human cancers. However, the existing studies always hold the assumption that full modalities are available.…

计算机视觉与模式识别 · 计算机科学 2025-03-19 Junjie Zhou , Jiao Tang , Yingli Zuo , Peng Wan , Daoqiang Zhang , Wei Shao

Latent variable models such as the Variational Auto-Encoder (VAE) have become a go-to tool for analyzing biological data, especially in the field of single-cell genomics. One remaining challenge is the interpretability of latent variables…

基因组学 · 定量生物学 2023-02-20 Romain Lopez , Nataša Tagasovska , Stephen Ra , Kyunghyn Cho , Jonathan K. Pritchard , Aviv Regev

The increasing availability of electrocardiogram (ECG) data has motivated the use of data-driven models for automating various clinical tasks based on ECG data. The development of subject-specific models are limited by the cost and…

机器学习 · 计算机科学 2018-08-07 Prashnna K Gyawali , B. Milan Horacek , John L. Sapp , Linwei Wang

Continuous treatment effect estimation holds significant practical importance across various decision-making and assessment domains, such as healthcare and the military. However, current methods for estimating dose-response curves hinge on…

机器学习 · 计算机科学 2024-06-05 Ruijing Cui , Jianbin Sun , Bingyu He , Kewei Yang , Bingfeng Ge

Simultaneous recordings from thousands of neurons across multiple brain areas reveal rich mixtures of activity that are shared between regions and dynamics that are unique to each region. Existing alignment or multi-view methods neglect…

Estimating causal effects from observational data is challenging, especially in the presence of latent confounders. Much work has been done on addressing this challenge, but most of the existing research ignores the bias introduced by the…

机器学习 · 计算机科学 2024-08-15 Yang Xie , Ziqi Xu , Debo Cheng , Jiuyong Li , Lin Liu , Yinghao Zhang , Zaiwen Feng

As in many fields of medical research, survival analysis has witnessed a growing interest in the application of deep learning techniques to model complex, high-dimensional, heterogeneous, incomplete, and censored medical data. Current…

机器学习 · 计算机科学 2023-12-25 Patricia A. Apellániz , Juan Parras , Santiago Zazo

As an important problem in causal inference, we discuss the identification and estimation of treatment effects (TEs) under limited overlap; that is, when subjects with certain features belong to a single treatment group. We use a latent…

机器学习 · 统计学 2022-04-22 Pengzhou Wu , Kenji Fukumizu

Optimal computations under uncertainty require an adequate probabilistic representation about beliefs. Deep generative models, and specifically Variational Autoencoders (VAEs), have the potential to meet this demand by building latent…

This paper introduces the Descriptive Variational Autoencoder (DVAE), an unsupervised and end-to-end trainable neural network for predicting vehicle trajectories that provides partial interpretability. The novel approach is based on the…

机器学习 · 计算机科学 2021-06-25 Marion Neumeier , Andreas Tollkühn , Thomas Berberich , Michael Botsch

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

统计方法学 · 统计学 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

Learning interpretable and disentangled representations of data is a key topic in machine learning research. Variational Autoencoder (VAE) is a scalable method for learning directed latent variable models of complex data. It employs a clear…

机器学习 · 计算机科学 2020-06-04 Andriy Serdega , Dae-Shik Kim

Estimating direct and indirect causal effects from observational data is crucial to understanding the causal mechanisms and predicting the behaviour under different interventions. Causal mediation analysis is a method that is often used to…

机器学习 · 计算机科学 2023-12-19 Ziqi Xu , Debo Cheng , Jiuyong Li , Jixue Liu , Lin Liu , Ke Wang

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

机器学习 · 计算机科学 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Advances in deep learning (DL) have resulted in impressive accuracy in some medical image classification tasks, but often deep models lack interpretability. The ability of these models to explain their decisions is important for fostering…

As an important problem in causal inference, we discuss the estimation of treatment effects (TEs). Representing the confounder as a latent variable, we propose Intact-VAE, a new variant of variational autoencoder (VAE), motivated by the…

机器学习 · 统计学 2022-04-22 Pengzhou Wu , Kenji Fukumizu

This study presents Latent Diffusion Autoencoder (LDAE), a novel encoder-decoder diffusion-based framework for efficient and meaningful unsupervised learning in medical imaging, focusing on Alzheimer disease (AD) using brain MR from the…

计算机视觉与模式识别 · 计算机科学 2026-01-12 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano , Henkjan Huisman

Self-supervised learning has attracted increasing attention as it learns data-driven representation from data without annotations. Vision transformer-based autoencoder (ViT-AE) by He et al. (2021) is a recent self-supervised learning…

计算机视觉与模式识别 · 计算机科学 2023-05-17 Chinmay Prabhakar , Hongwei Bran Li , Jiancheng Yang , Suprosana Shit , Benedikt Wiestler , Bjoern Menze
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