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Bone marrow cytology is required to make a hematological diagnosis, influencing critical clinical decision points in hematology. However, bone marrow cytology is tedious, limited to experienced reference centers and associated with high…

图像与视频处理 · 电气工程与系统科学 2021-07-09 Rohollah Moosavi Tayebi , Youqing Mu , Taher Dehkharghanian , Catherine Ross , Monalisa Sur , Ronan Foley , Hamid R. Tizhoosh , Clinton JV Campbell

Cell shape analysis is important in biomedical research. Deep learning methods may perform to segment individual cells if they use sufficient training data that the boundary of each cell is annotated. However, it is very time-consuming for…

图像与视频处理 · 电气工程与系统科学 2020-02-26 Kazuya Nishimura , Dai Fei Elmer Ker , Ryoma Bise

Gastrointestinal (GI) bleeding is a serious medical condition that presents significant diagnostic challenges, particularly in settings with limited access to healthcare resources. Wireless Capsule Endoscopy (WCE) has emerged as a powerful…

计算机视觉与模式识别 · 计算机科学 2024-12-25 S. Balasubramanian , Ammu Abhishek , Yedu Krishna , Darshan Gera

Blood related invasive pathological investigations play a major role in diagnosis of diseases. But in India and other third world countries there are no enough pathological infrastructures for medical diagnosis. Moreover, most of the remote…

计算机与社会 · 计算机科学 2013-12-04 Pramit Ghosh , Debotosh Bhattacharjee , Mita Nasipuri , Dipak Kumar Basu

Diagnosing basal cell carcinomas (BCC), one of the most common cutaneous malignancies in humans, is a task regularly performed by pathologists and dermato-pathologists. Improving histological diagnosis by providing diagnosis suggestions,…

Our goal is to bridge human and machine intelligence in melanoma detection. We develop a classification system exploiting a combination of visual pre-processing, deep learning, and ensembling for providing explanations to experts and to…

Red blood cells are highly deformable and present in various shapes. In blood cell disorders, only a subset of all cells is morphologically altered and relevant for the diagnosis. However, manually labeling of all cells is laborious,…

计算机视觉与模式识别 · 计算机科学 2020-07-24 Ario Sadafi , Asya Makhro , Anna Bogdanova , Nassir Navab , Tingying Peng , Shadi Albarqouni , Carsten Marr

Cell instance segmentation is critical to analyzing biomedical images, yet accurately distinguishing tightly touching cells remains a persistent challenge. Existing instance segmentation frameworks, including detection-based, contour-based,…

计算机视觉与模式识别 · 计算机科学 2025-06-12 Ye Zhang , Yu Zhou , Yifeng Wang , Jun Xiao , Ziyue Wang , Yongbing Zhang , Jianxu Chen

Brain tumor segmentation intends to delineate tumor tissues from healthy brain tissues. The tumor tissues include necrosis, peritumoral edema, and active tumor. In contrast, healthy brain tissues include white matter, gray matter, and…

图像与视频处理 · 电气工程与系统科学 2020-06-03 Snehal Rajput , Mehul S Raval

Automatic instance segmentation is a problem that occurs in many biomedical applications. State-of-the-art approaches either perform semantic segmentation or refine object bounding boxes obtained from detection methods. Both suffer from…

计算机视觉与模式识别 · 计算机科学 2020-04-22 Long Chen , Martin Strauch , Dorit Merhof

In this paper, we propose a new model to segment cells in phase contrast microscopy images. Cell images collected from the similar scenario share a similar background. Inspired by this, we separate cells from the background in images by…

计算机视觉与模式识别 · 计算机科学 2019-04-02 Lin Zhang

Histopathology images contain essential information for medical diagnosis and prognosis of cancerous disease. Segmentation of glands in histopathology images is a primary step for analysis and diagnosis of an unhealthy patient. Due to the…

图像与视频处理 · 电气工程与系统科学 2019-09-04 Safiyeh Rezaei , Ali Emami , Hamidreza Zarrabi , Shima Rafiei , Kayvan Najarian , Nader Karimi , Shadrokh Samavi , S. M. Reza Soroushmehr

Leukemia is a hematologic cancer which develops in blood tissue and triggers rapid production of immature and abnormal shaped white blood cells. Based on statistics it is found that the leukemia is one of the leading causes of death in men…

计算机视觉与模式识别 · 计算机科学 2018-03-28 Sachin Kumar , Sumita Mishra , Pallavi Asthana , Pragya

In digital pathology, both detection and classification of cells are important for automatic diagnostic and prognostic tasks. Classifying cells into subtypes, such as tumor cells, lymphocytes or stromal cells is particularly challenging.…

计算机视觉与模式识别 · 计算机科学 2022-06-07 Shahira Abousamra , David Belinsky , John Van Arnam , Felicia Allard , Eric Yee , Rajarsi Gupta , Tahsin Kurc , Dimitris Samaras , Joel Saltz , Chao Chen

With the advent of novel cancer treatment options such as immunotherapy, studying the tumour immune micro-environment (TIME) is crucial to inform on prognosis and understand potential response to therapeutic agents. A key approach to…

Extracting single-cell information from microscopy data requires accurate instance-wise segmentations. Obtaining pixel-wise segmentations from microscopy imagery remains a challenging task, especially with the added complexity of…

计算机视觉与模式识别 · 计算机科学 2024-01-02 Christoph Reich , Tim Prangemeier , André O. Françani , Heinz Koeppl

Parkinson's disease (PD) is a neurodegenerative disorder associated with the accumulation of misfolded alpha-synuclein aggregates, forming Lewy bodies and neuritic shape used for pathology diagnostics. Automatic analysis of…

图像与视频处理 · 电气工程与系统科学 2025-12-23 Erwan Dereure , Robin Louiset , Laura Parkkinen , David A Menassa , David Holcman

Segmentation, or the outlining of objects within images, is a critical step in the measurement and analysis of cells within microscopy images. While improvements continue to be made in tools that rely on classical methods for segmentation,…

定量方法 · 定量生物学 2024-03-15 Nodar Gogoberidze , Beth A. Cimini

Segmentation of objects in microscopy images is required for many biomedical applications. We introduce object-centric embeddings (OCEs), which embed image patches such that the spatial offsets between patches cropped from the same object…

机器学习 · 计算机科学 2023-10-13 Steffen Wolf , Manan Lalit , Henry Westmacott , Katie McDole , Jan Funke

Leukemia, the cancer of blood cells, originates in the blood-forming cells of the bone marrow. In Chronic Myeloid Leukemia (CML) conditions, the cells partially become mature that look like normal white blood cells but do not resist…

基因组学 · 定量生物学 2023-02-09 Madiha Hameed , Muhammad Bilal , Tuba Majid , Abdul Majid , Asifullah Khan