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In real-world practice, medical images acquired in different phases possess complementary information, {\em e.g.}, radiologists often refer to both arterial and venous scans in order to make the diagnosis. However, in medical image…

计算机视觉与模式识别 · 计算机科学 2019-09-13 Huangjie Zheng , Lingxi Xie , Tianwei Ni , Ya Zhang , Yan-Feng Wang , Qi Tian , Elliot K. Fishman , Alan L. Yuille

The ability to measure the transcriptomes of single cells has only been feasible for a few years, and is becoming an extremely popular assay. While many types of analysis and questions can be answered using single cell RNA-sequencing, a…

基因组学 · 定量生物学 2017-08-09 Valentine Svensson , Roser Vento-Tormo , Sarah A Teichmann

Single-cell RNA-seq provides detailed molecular snapshots of individual cells but is notoriously noisy. Variability stems from biological differences and technical factors, such as amplification bias and limited RNA capture efficiency,…

机器学习 · 计算机科学 2026-02-27 Victor Chardès

The automated analysis of microscopy images is a challenge in the context of single-cell tracking and quantification. This work has as goals the study of the performance of deep learning for segmenting microscopy images and the improvement…

定量方法 · 定量生物学 2022-10-05 André O. Françani

Consistency learning plays a crucial role in semi-supervised medical image segmentation as it enables the effective utilization of limited annotated data while leveraging the abundance of unannotated data. The effectiveness and efficiency…

计算机视觉与模式识别 · 计算机科学 2023-05-26 Zhenxi Zhang , Ran Ran , Chunna Tian , Heng Zhou , Xin Li , Fan Yang , Zhicheng Jiao

Different from the conventional deep learning work based on an images content in computer vision, deep steganalysis is an art to detect the secret information embedded in an image via deep learning, pose challenge of detection weak…

多媒体 · 计算机科学 2018-04-19 Jianhua Yang , Yun-Qing Shi , Edward K. Wong , Xiangui Kang

Semantic segmentation, like other fields of computer vision, has seen a remarkable performance advance by the use of deep convolution neural networks. However, considering that neighboring pixels are heavily dependent on each other, both…

计算机视觉与模式识别 · 计算机科学 2017-08-08 Hyojin Park , Jisoo Jeong , Youngjoon Yoo , Nojun Kwak

Modern datasets arising from social media, genomics, and biomedical informatics are often heterogeneous and (ultra) high-dimensional, creating substantial challenges for conventional modeling techniques. Quantile regression (QR) not only…

统计方法学 · 统计学 2026-01-07 Hanqing Wu , Jonas Wallin , Iuliana Ionita-Laza

Important tasks in the study of genomic data include the identification of groups of similar cells (for example by clustering), and visualisation of data summaries (for example by dimensional reduction). In this paper, we develop a novel…

统计方法学 · 统计学 2024-10-15 Thomas E. Bartlett , Swati Chandna , Sandipan Roy

Cancer is a complex disease characterized by uncontrolled cell growth and proliferation. T cell receptors (TCRs) are essential proteins for the adaptive immune system, and their specific recognition of antigens plays a crucial role in the…

机器学习 · 计算机科学 2023-09-07 Zahra Tayebi , Sarwan Ali , Prakash Chourasia , Taslim Murad , Murray Patterson

Semi-supervised clustering techniques have emerged as valuable tools for leveraging prior information in the form of constraints to improve the quality of clustering outcomes. Despite the proliferation of such methods, the ability to…

机器学习 · 计算机科学 2023-12-19 Guangjie Zeng , Hao Peng , Angsheng Li , Zhiwei Liu , Runze Yang , Chunyang Liu , Lifang He

The use of deep learning models in computational biology has increased massively in recent years, and it is expected to continue with the current advances in the fields such as Natural Language Processing. These models, although able to…

Convolutional Neural Networks (CNN) has achieved a great success in image recognition task by automatically learning a hierarchical feature representation from raw data. While the majority of Time-Series Classification (TSC) literature is…

计算机视觉与模式识别 · 计算机科学 2017-10-10 Nima Hatami , Yann Gavet , Johan Debayle

The exploration of selected single nucleotide polymorphisms (SNPs) to identify genetic diversity between different sequencing population pools (Pool-seq) is a fundamental task in genetic research. As underlying sequence reads and their…

基因组学 · 定量生物学 2021-01-05 Julia Siekiera , Stefan Kramer

Recent advances in high-resolution sequencing have paved the way for population-scale analysis in single-cell RNA-sequencing (scRNA-seq) data. scRNA-seq data, in particular, have proven to be extremely powerful in profiling a variety of…

统计方法学 · 统计学 2025-10-30 Hanxuan Ye , Zachary Qian , Hongzhe Li

Face recognition is the important field in machine learning and pattern recognition research area. It has a lot of applications in military, finance, public security, to name a few. In this paper, the combination of the tensor sparse PCA…

计算机视觉与模式识别 · 计算机科学 2020-08-12 Loc Hoang Tran , Linh Hoang Tran

Dimensionality reduction methods such as t-SNE and UMAP are popular methods for visualizing data with a potential (latent) clustered structure. They are known to group data points at the same time as they embed them, resulting in…

机器学习 · 计算机科学 2025-09-04 Elizabeth Coda , Ery Arias-Castro , Gal Mishne

Principal component analysis (PCA), the most popular dimension-reduction technique, has been used to analyze high-dimensional data in many areas. It discovers the homogeneity within the data and creates a reduced feature space to capture as…

统计方法学 · 统计学 2026-03-24 Daning Bi , Le Chang , Yanrong Yang

Graph Convolutional Networks (GCNs) are recently getting much attention in bioinformatics and chemoinformatics as a state-of-the-art machine learning approach with high accuracy. GCNs process convolutional operations along with graph…

分布式、并行与集群计算 · 计算机科学 2019-03-28 Yusuke Nagasaka , Akira Nukada , Ryosuke Kojima , Satoshi Matsuoka

Improved understanding of charge-transport in single molecules is essential for harnessing the potential of molecules e.g. as circuit components at the ultimate size limit. However, interpretation and analysis of the large, stochastic…

介观与纳米尺度物理 · 物理学 2020-08-06 Nathan D. Bamberger , Jeffrey A. Ivie , Keshaba N. Parida , Dominic V. McGrath , Oliver L. A. Monti