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相关论文: Prospects of Single-Cell NMR Spectroscopy with Qua…

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Quantum technologies have seen a rapid developmental surge over the last couple of years. Though often overshadowed by quantum computation, quantum sensors show tremendous potential for widespread applications in chemistry and biology. One…

量子物理 · 物理学 2022-05-30 Robin D. Allert , Karl D. Briegel , Dominik B. Bucher

Single-molecule technology stands as a powerful tool, enabling the characterization of intricate structural and dynamic information that would otherwise remain concealed within the averaged behaviors of numerous molecules. This technology…

量子物理 · 物理学 2025-01-08 Jiangfeng Du , Fazhan Shi , Xi Kong , Fedor Jekezko , Jörg Wrachtrup

Nanomagnetometry using the nitrogen-vacancy (NV) centre in diamond has attracted a great deal of interest because of the combined features of room temperature operation, nanoscale resolution and high sensitivity. One of the important goals…

Characterization of the molecular properties of surfaces under ambient or chemically reactive conditions is a fundamental scientific challenge. Moreover, many traditional analytical techniques used for probing surfaces often lack dynamic or…

Optically-probed nitrogen-vacancy (NV) quantum defects in diamond can detect nuclear magnetic resonance (NMR) signals with high-spectral resolution from micron-scale sample volumes of about 10 picoliters. However, a key challenge for NV-NMR…

Nitrogen-vacancy (NV) centers in diamond have emerged as quantum sensors capable of detecting nuclear magnetic resonance (NMR) signals at unprecedented length scales, ranging from picoliter sample volumes down to single spins at the diamond…

化学物理 · 物理学 2025-01-07 Nick R. von Grafenstein , Karl D. Briegel , Jorge Casanova , Dominik B. Bucher

Nuclear magnetic resonance (NMR) spectroscopy has approached the limit of single molecule sensitivity, however the spectral resolution is currently insufficient to obtain detailed information on chemical structure and molecular…

量子物理 · 物理学 2015-08-19 Xi Kong , Alexander Stark , Jiangfeng Du , Liam P. McGuinness , Fedor Jelezko

Advances in sensing devices that utilize nitrogen-vacancy (NV) center ensembles in diamond are driving progress in microscale nuclear magnetic resonance spectroscopy. Utilizing quantum sensing techniques in the high-field regime…

量子物理 · 物理学 2025-10-22 Ainitze Biteri-Uribarren , Ana Martin , Jorge Casanova

Identification of individual cells within heterogeneous populations is essential for biomedical research and clinical diagnostics. Conventional labeling-based sorting methods, such as fluorescence-activated cell sorting and…

Nuclear magnetic resonance (NMR) spectroscopy is a widely used tool for chemical analysis and molecular structure identification. Because it typically relies on the weak magnetic fields produced by a small thermal nuclear spin polarization,…

Conventional nuclear magnetic resonance (NMR) spectroscopy relies on acquiring signal from a macroscopic ensemble of molecules to gain information about molecular structure and dynamics. Transferring this technique to nanoscale sample sizes…

介观与纳米尺度物理 · 物理学 2019-02-06 Jeffrey Holzgrafe , Qiushi Gu , Jan Beitner , Dhiren Kara , Helena S. Knowles , Mete Atatüre

Nitrogen-vacancy (NV) based quantum sensors hold great potential for real-time single-cell sensing with far-reaching applications in fundamental biology and medical diagnostics. Although highly sensitive, the mapping of quantum measurements…

Powered by the mutual developments in instrumentation, materials andtheoretical descriptions, sensing and imaging capabilities of quantum emitters insolids have significantly increased in the past two decades. Quantum emitters insolids,…

应用物理 · 物理学 2019-09-11 Mariusz Radtke , Ettore Bernardi , Abdallah Slablab , Richard Nelz , Elke Neu

Nuclear magnetic resonance (NMR) imaging with shallow nitrogen-vacancy (NV) centers in diamond offers an exciting route toward sensitive and localized chemical characterization at the nanoscale. Remarkable progress has been made to combat…

Quantum sensing using optically addressable atomic-scale defects, such as the nitrogen--vacancy (NV) center in diamond, provides new opportunities for sensitive and highly localized characterization of chemical functionality. Notably,…

Quantum sensors based on nitrogen-vacancy centers in diamond have emerged as a promising detection modality for nuclear magnetic resonance (NMR) spectroscopy owing to their micron-scale detection volume and non-inductive based detection. A…

Nuclear magnetic resonance (NMR) spectroscopy is, in principle, a promising candidate to study the intracellular chemistry of single microscopic living entities. However, due to sensitivity limitations, NMR experiments were reported only on…

生物物理 · 物理学 2015-11-23 Marco Grisi , Beatrice Volpe , Roberto Guidetti , Nicola Harris , Giovanni Boero

Sensing of signals from biological processes, such as action potential propagation in nerves, are essential for clinical diagnosis and basic understanding of physiology. Sensing can be performed electrically by placing sensor probes near or…

Quantum sensors based on the nitrogen-vacancy (NV) centre in diamond are rapidly advancing from scientific exploration towards the first generation of commercial applications. While significant progress has been made in developing suitable…

A single nitrogen-vacancy (NV) center in diamond is a prime candidate for a solid-state quantum magnetometer capable of detecting single nuclear spins with prospective application to nuclear magnetic resonance (NMR) at the nanoscale.…

量子物理 · 物理学 2020-02-07 Daiki Misonou , Kento Sasaki , Shuntaro Ishizu , Yasuaki Monnai , Kohei M. Itoh , Eisuke Abe
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