相关论文: Toward more accurate and generalizable brain defor…
Brain strain and strain rate are effective in predicting traumatic brain injury (TBI) caused by head impacts. However, state-of-the-art finite element modeling (FEM) demands considerable computational time in the computation, limiting its…
Strain and strain rate are effective traumatic brain injury predictors. Kinematics-based models estimating these metrics suffer from significant different distributions of both kinematics and the injury metrics across head impact types. To…
Objective: Many recent studies have suggested that brain deformation resulting from a head impact is linked to the corresponding clinical outcome, such as mild traumatic brain injury (mTBI). Even though several finite element (FE) head…
Brain deformation caused by a head impact leads to traumatic brain injury (TBI). The maximum principal strain (MPS) was used to measure the extent of brain deformation and predict injury, and the recent evidence has indicated that…
Purpose: Computational head models are essential tools for studying the risk of mild traumatic brain injury (mTBI) under different activities and across populations. However, different computational models incorporate varied levels of…
Traumatic brain injury (TBI) is a complex injury that is hard to predict and diagnose, with many studies focused on associating head kinematics to brain injury risk. Recently, there has been a push towards using computationally expensive…
Mild traumatic brain injury is a growing public health problem with an estimated incidence of over 1.7 million people annually in US. Diagnosis is based on clinical history and symptoms, and accurate, concrete measures of injury are…
Head motion induced by impacts has been deemed as one of the most important measures in brain injury prediction, given that the majority of brain injury metrics use head kinematics as input. Recently, researchers have focused on using fast…
Brain midline shift (MLS) is one of the most critical factors to be considered for clinical diagnosis and treatment decision-making for intracranial hemorrhage. Existing computational methods on MLS quantification not only require intensive…
Objective: Traumatic brain injury can be caused by head impacts, but many brain injury risk estimation models are not equally accurate across the variety of impacts that patients may undergo and the characteristics of different types of…
Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…
Supervised learning algorithms trained on medical images will often fail to generalize across changes in acquisition parameters. Recent work in domain adaptation addresses this challenge and successfully leverages labeled data in a source…
Traumatic brain injury (TBI) presents a significant public health challenge, often resulting in mortality or lasting disability. Predicting outcomes such as mortality and Functional Status Scale (FSS) scores can enhance treatment strategies…
Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted…
Mild traumatic brain injuries (mTBI) are a highly prevalent condition with heterogeneous outcomes between individuals. A key factor governing brain tissue deformation and the risk of mTBI is the rotational kinematics of the head.…
Prognoses of Traumatic Brain Injury (TBI) outcomes are neither easily nor accurately determined from clinical indicators. This is due in part to the heterogeneity of damage inflicted to the brain, ultimately resulting in diverse and complex…
Mild Traumatic Brain Injuries (mTBI) are caused by violent head motions or impacts. Most mTBI prevention strategies explicitly or implicitly rely on a "brain injury criterion". A brain injury criterion takes some descriptor of the head's…
Background: High-resolution MRI is critical for diagnosis, but long acquisition times limit clinical use. Super-resolution (SR) can enhance resolution post-scan, yet existing deep learning methods face fidelity-efficiency trade-offs.…
The segmentation of lesions in Moderate to Severe Traumatic Brain Injury (msTBI) presents a significant challenge in neuroimaging due to the diverse characteristics of these lesions, which vary in size, shape, and distribution across brain…
Magnetic Resonance Imaging (MRI) sequences provide rich spatial and frequency domain information, which is crucial for accurate lesion classification in medical imaging. However, effectively integrating multi-sequence MRI data for robust 3D…