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Medical machine learning algorithms are typically evaluated based on accuracy vs. a clinician-defined ground truth, a reasonable initial choice since trained clinicians are usually better classifiers than ML models. However, this metric…

机器学习 · 计算机科学 2024-05-21 Charles B. Delahunt , Courosh Mehanian , Matthew P. Horning

Machine learning (ML) involves private data and proprietary model parameters. MPC-based ML allows multiple parties to collaboratively run an ML workload without sharing their private data or model parameters using multi-party computing…

密码学与安全 · 计算机科学 2025-11-26 Jinyu Liu , Gang Tan , Kiwan Maeng

Machine learning (ML) models show strong promise for new biomedical prediction tasks, but concerns about trustworthiness have hindered their clinical adoption. In particular, it is often unclear whether a model relies on true clinical cues…

机器学习 · 计算机科学 2026-01-13 Dushan N. Wadduwage , Dineth Jayakody , Leonidas Zimianitis

Autonomous research systems capable of generating complete scientific manuscripts have advanced rapidly, yet robust and realistic evaluation frameworks have failed to keep pace. To bridge this gap, we introduce MLReplicate, an end-to-end…

机器学习 · 计算机科学 2026-05-19 Sasi Kiran Gaddipati , Diyana Muhammed , Farhana Keya , Gollam Rabby , Sören Auer

YAMLE: Yet Another Machine Learning Environment is an open-source framework that facilitates rapid prototyping and experimentation with machine learning (ML) models and methods. The key motivation is to reduce repetitive work when…

机器学习 · 计算机科学 2024-02-12 Martin Ferianc , Miguel Rodrigues

Data-driven modeling based on Machine Learning (ML) is becoming a central component of protein engineering workflows. This perspective presents the elements necessary to develop effective, reliable, and reproducible ML models, and a set of…

生物大分子 · 定量生物学 2025-07-11 Fabio Herrera-Rocha , David Medina-Ortiz , Fabian Mauz , Juergen Pleiss , Mehdi D. Davari

Clinical and biomedical research in low-resource settings often faces significant challenges due to the need for high-quality data with sufficient sample sizes to construct effective models. These constraints hinder robust model training…

Given the inherent non-deterministic nature of machine learning (ML) systems, their behavior in production environments can lead to unforeseen and potentially dangerous outcomes. For a timely detection of unwanted behavior and to prevent…

软件工程 · 计算机科学 2025-10-01 Hira Naveed , John Grundy , Chetan Arora , Hourieh Khalajzadeh , Omar Haggag

Reliable identification of molecular biomarkers is essential for accurate patient stratification. While state-of-the-art machine learning approaches for sample classification continue to push boundaries in terms of performance, most of…

分子网络 · 定量生物学 2019-11-07 Matteo Manica , Joris Cadow , Roland Mathis , María Rodríguez Martínez

New medical treatment development requires multiple phases of clinical trials. Despite the significant human and financial costs of bringing a drug to market, less than 20% of drugs in testing will make it from the first phase to final…

计算与语言 · 计算机科学 2024-08-21 Michael Reinisch , Jianfeng He , Chenxi Liao , Sauleh Ahmad Siddiqui , Bei Xiao

Machine learning research depends on objectively interpretable, comparable, and reproducible algorithm benchmarks. We advocate the use of curated, comprehensive suites of machine learning tasks to standardize the setup, execution, and…

Nowadays, machine learning (ML) is being used in software systems with multiple application fields, from medicine to software engineering (SE). On the one hand, the popularity of ML in the industry can be seen in the statistics showing its…

软件工程 · 计算机科学 2023-05-09 Anamaria Mojica-Hanke

Estimating treatment effects from observational data provides insights about causality guiding many real-world applications such as different clinical study designs, which are the formulations of trials, experiments, and observational…

机器学习 · 计算机科学 2022-03-11 Zhixuan Chu , Stephen L. Rathbun , Sheng Li

Performance comparison of supervised machine learning (ML) models are widely done in terms of different confusion matrix based scores obtained on test datasets. However, a dataset comprises several instances having different difficulty…

机器学习 · 计算机科学 2022-09-27 Anupam Biswas

A key challenge in developing and deploying Machine Learning (ML) systems is understanding their performance across a wide range of inputs. To address this challenge, we created the What-If Tool, an open-source application that allows…

机器学习 · 计算机科学 2019-10-04 James Wexler , Mahima Pushkarna , Tolga Bolukbasi , Martin Wattenberg , Fernanda Viegas , Jimbo Wilson

Advancements in scientific instrument sensors and connected devices provide unprecedented insight into ongoing experiments and present new opportunities for control, optimization, and steering. However, the diversity of sensors and…

分布式、并行与集群计算 · 计算机科学 2022-05-04 Jakob R. Elias , Ryan Chard , Maksim Levental , Zhengchun Liu , Ian Foster , Santanu Chaudhuri

The development and deployment of machine learning (ML) systems can be executed easily with modern tools, but the process is typically rushed and means-to-an-end. The lack of diligence can lead to technical debt, scope creep and misaligned…

The growing adoption and deployment of Machine Learning (ML) systems came with its share of ethical incidents and societal concerns. It also unveiled the necessity to properly audit these systems in light of ethical principles. For such a…

Reliable seizure detection is critical for diagnosing and managing epilepsy, yet clinical workflows remain dependent on time-consuming manual EEG interpretation. While machine learning has shown promise, existing approaches often rely on…

While machine learning (ML) methods have received a lot of attention in recent years, these methods are primarily for prediction. Empirical researchers conducting policy evaluations are, on the other hand, pre-occupied with causal problems,…

机器学习 · 统计学 2019-03-04 Noemi Kreif , Karla DiazOrdaz
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