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We present the first general purpose framework for marginal maximum a posteriori estimation of probabilistic program variables. By using a series of code transformations, the evidence of any probabilistic program, and therefore of any…

机器学习 · 统计学 2017-07-17 Tom Rainforth , Tuan Anh Le , Jan-Willem van de Meent , Michael A. Osborne , Frank Wood

Risk prediction is central to both clinical medicine and public health. While many machine learning models have been developed to predict mortality, they are rarely applied in the clinical literature, where classification tasks typically…

机器学习 · 统计学 2017-12-05 Maggie Makar , Marzyeh Ghassemi , David Cutler , Ziad Obermeyer

In Bayesian accelerated life testing, the most used tool for model comparison is the deviance information criterion. An alternative and more formal approach is to use Bayes factors to compare models. However, Bayesian accelerated life…

统计方法学 · 统计学 2026-01-16 Neill Smit , Lizanne Raubenheimer

Two fundamental research tasks in science and engineering are forward predictions and data inversion. This article introduces a recent R package RobustCalibration for Bayesian data inversion and model calibration by experiments and field…

统计计算 · 统计学 2024-02-20 Mengyang Gu

Background: Mathematical models based on ordinary differential equations (ODEs) are essential tools across various scientific disciplines, including biology, ecology, and healthcare informatics. They are used to simulate complex dynamic…

定量方法 · 定量生物学 2025-09-03 Hamed Karami , Amanda Bleichrodt , Ruiyan Luo , Gerardo Chowell

A new stochastic method for describing mortality is proposed and explored. It is based on differences of observed times series of the transform $\log(-\log x)$ of survival probabilities which seem to follow simple patterns over the years.…

应用统计 · 统计学 2015-02-26 Meitner Cadena

In this article, we introduce the BNPqte R package which implements the Bayesian nonparametric approach of Xu, Daniels and Winterstein (2018) for estimating quantile treatment effects in observational studies. This approach provides…

统计计算 · 统计学 2021-06-29 Chuji Luo , Michael J. Daniels

A novel data-driven methodology is presented for the joint selection of prior parameters for both fixed and random effects in Linear Mixed Models (LMMs). This approach facilitates the estimation of complex random-effects structures, as well…

统计方法学 · 统计学 2026-04-28 Matteo Amestoy , R. Vermeulen , Mark A. van de Wiel , Wessel N. van Wieringen

Integrating multiple observational studies for meta-analysis has sparked much interest. The presented R package WMAP (Weighted Meta-Analysis with Pseudo-Population) addresses a critical gap in the implementation of integrative weighting…

统计方法学 · 统计学 2025-07-01 Subharup Guha , Mengqi Xu , Kashish Priyam , Yi Li

Discrete biomarkers derived as cell densities or counts from tissue microarrays and immunostaining are widely used to study immune signatures in relation to survival outcomes in cancer. Although routinely collected, these signatures are not…

\noindent The modal age at death is an increasingly used measure for understanding longevity and mortality patterns. However, existing estimation methods focus on point estimates, overlooking the inherent variability and uncertainty in…

应用统计 · 统计学 2025-10-07 Silvio C. Patricio , Paola Vazquez-Castillo

Many scientific and engineering applications require fitting regression models that are nonlinear in the parameters. Advances in computer hardware and software in recent decades have made it easier to fit such models. Relative to fitting…

统计方法学 · 统计学 2024-03-20 Peng Liu , William Q. Meeker

The software package $\texttt{mstate}$, in articulation with the package $\texttt{survival}$, provides not only a well-established multi-state survival analysis framework in R, but also one of the most complete, as it includes point and…

统计计算 · 统计学 2022-01-21 Rui J. Costa , Moritz Gerstung

We present a Bayesian nonparametric system reliability model which scales well and provides a great deal of flexibility in modeling. The Bayesian approach naturally handles the disparate amounts of component and subsystem data that may…

统计方法学 · 统计学 2022-03-22 Richard L. Warr , Jeremy M. Meyer , Jackson T. Curtis

Clinical decision making regarding treatments based on personal characteristics leads to effective health improvements. Machine learning (ML) has been the primary concern of diagnosis support according to comprehensive patient information.…

Accurate forecasts of weekly mortality are essential for public health and the insurance industry. We develop a forecasting framework that extends the Lee-Carter model with age- and region-specific seasonal effects and penalized distributed…

应用统计 · 统计学 2026-05-22 Jens Robben , Karim Barigou

Modern epidemiological analytics increasingly use machine learning models that offer strong prediction but often lack calibrated uncertainty. Bayesian methods provide principled uncertainty quantification, yet are viewed as difficult to…

机器学习 · 统计学 2025-11-18 Debashis Chatterjee

Demographic projections of future mortality rates involve a high level of uncertainty and require stochastic mortality models. The current paper investigates forward mortality models driven by a (possibly infinite dimensional) Wiener…

概率论 · 数学 2025-11-21 Stefan Tappe , Stefan Weber

Bayesian networks are a class of models that are widely used for risk assessment of complex operational systems. There are now multiple approaches, as well as implemented software, that guide their construction via data learning or expert…

统计方法学 · 统计学 2021-07-27 Manuele Leonelli , Ramsiya Ramanathan , Rachel L. Wilkerson

BAYES-LIN is an extension of the LISP-STAT object-oriented statistical computing environment, which adds to LISP-STAT some object prototypes appropriate for carrying out local computation via message-passing between clique-tree nodes of…

数据分析、统计与概率 · 物理学 2007-05-23 Darren J Wilkinson