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Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

流体动力学 · 物理学 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…

Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…

We propose a fully automated algorithm based on a deep learning framework enabling screening of a coronary computed tomography angiography (CCTA) examination for confident detection of the presence or absence of coronary artery…

图像与视频处理 · 电气工程与系统科学 2020-06-09 Sema Candemir , Richard D. White , Mutlu Demirer , Vikash Gupta , Matthew T. Bigelow , Luciano M. Prevedello , Barbaros S. Erdal

Accurate and rapid estimation of hemodynamic metrics, such as pressure and wall shear stress (WSS), is important for assessing the severity of Coronary Artery Disease (CAD). Existing approaches, including invasive Fractional Flow Reserve…

计算工程、金融与科学 · 计算机科学 2026-05-28 Reza Akbarian Bafghi , Sukirt Thakur , Maziar Raissi

Background and Objective: Hemodynamic analysis of blood flow through arteries and veins is critical for diagnosing cardiovascular diseases, such as aneurysms and stenoses, and for investigating cardiovascular parameters, such as turbulence…

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

机器学习 · 计算机科学 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

Computational Fluid Dynamics (CFD) simulations are a very important tool for many industrial applications, such as aerodynamic optimization of engineering designs like cars shapes, airplanes parts etc. The output of such simulations, in…

计算机视觉与模式识别 · 计算机科学 2021-03-12 Theodoros Georgiou , Sebastian Schmitt , Thomas Bäck , Nan Pu , Wei Chen , Michael Lew

Coronary artery disease (CAD) is one of the most common causes of death in the European Union and the USA. The crucial biomarker in its diagnosis is called Fractional Flow Reserve (FFR) and its in-vivo measurement is obtained via an…

图像与视频处理 · 电气工程与系统科学 2024-05-22 Patryk Rygiel

Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…

机器学习 · 计算机科学 2026-01-30 Yiying Sheng , Wenhao Ding , Dylan Roi , Leonard Leong Litt Yeo , Hwa Liang Leo , Choon Hwai Yap

Computational fluid dynamics (CFD) models of blood flow in the left ventricle (LV) and aorta are important tools for analyzing the mechanistic links between myocardial deformation and flow patterns. Typically, the use of image-based…

The emergence of computational fluid dynamics (CFD) enabled the simulation of intricate transport processes, including flow in physiological structures, such as blood vessels. While these so-called hemodynamic simulations offer…

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

计算机视觉与模式识别 · 计算机科学 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

计算物理 · 物理学 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

The heart is the central part of the cardiovascular network. Its role is to pump blood to various body organs. Many cardiovascular diseases occur due to an abnormal functioning of the heart. A diseased heart leads to severe complications…

医学物理 · 物理学 2024-11-19 Mahesh S. Nagargoje , Eneko Lazpita , Jesús Garicano-Mena , Soledad Le Clainche

We present a novel deep learning framework for flow field predictions in irregular domains when the solution is a function of the geometry of either the domain or objects inside the domain. Grid vertices in a computational fluid dynamics…

机器学习 · 计算机科学 2021-09-20 Ali Kashefi , Davis Rempe , Leonidas J. Guibas

Image-based computational fluid dynamics (CFD) has emerged as a powerful tool to study cardiovascular flows while 2D echocardiography (echo) is the most widely used non-invasive imaging modality for diagnosis of heart disease. Here, echo is…

Predictive modeling of blood flow and pressure have numerous applications ranging from non-invasive assessment of functional significance of disease to planning invasive procedures. While several such predictive modeling techniques have…

Cerebral aneurysms are pathological dilations of intracranial arteries that can rupture with devastating consequences, including subarachnoid hemorrhage, stroke, and death. Accumulating evidence indicates that local hemodynamic forces play…

其他定量生物学 · 定量生物学 2025-05-22 Reza Bozorgpour , Pilwan Kim

Cerebral autoregulation plays a key physiological role by limiting blood flow changes in the face of pressure fluctuations. Although the involved cellular processes are mechanically driven, the quantification of haemodynamic forces in…

定量方法 · 定量生物学 2024-11-15 Alberto Coccarelli , Ioannis Polydoros , Alex Drysdale , Osama F. Harraz , Chennakesava Kadapa