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Multiple instance learning (MIL) has become a standard paradigm for the weakly supervised classification of whole slide images (WSIs). However, this paradigm relies on using a large number of labeled WSIs for training. The lack of training…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Minghao Han , Linhao Qu , Dingkang Yang , Xukun Zhang , Xiaoying Wang , Lihua Zhang

Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical…

计算机视觉与模式识别 · 计算机科学 2024-07-16 Linhao Qu , Dingkang Yang , Dan Huang , Qinhao Guo , Rongkui Luo , Shaoting Zhang , Xiaosong Wang

Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Jayanie Bogahawatte , Sachith Seneviratne , Saman Halgamuge

Computer-aided Whole Slide Image (WSI) classification has the potential to enhance the accuracy and efficiency of clinical pathological diagnosis. It is commonly formulated as a Multiple Instance Learning (MIL) problem, where each WSI is…

计算机视觉与模式识别 · 计算机科学 2025-04-17 Linhao Qu , Shiman Li , Xiaoyuan Luo , Shaolei Liu , Qinhao Guo , Manning Wang , Zhijian Song

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

计算机视觉与模式识别 · 计算机科学 2025-03-24 Devavrat Tomar , Guillaume Vray , Dwarikanath Mahapatra , Sudipta Roy , Jean-Philippe Thiran , Behzad Bozorgtabar

Whole slide pathology image classification presents challenges due to gigapixel image sizes and limited annotation labels, hindering model generalization. This paper introduces a prompt learning method to adapt large vision-language models…

Whole Slide Image (WSI) classification is often formulated as a Multiple Instance Learning (MIL) problem. Recently, Vision-Language Models (VLMs) have demonstrated remarkable performance in WSI classification. However, existing methods…

计算机视觉与模式识别 · 计算机科学 2024-04-08 Hao Li , Ying Chen , Yifei Chen , Wenxian Yang , Bowen Ding , Yuchen Han , Liansheng Wang , Rongshan Yu

The expensive fine-grained annotation and data scarcity have become the primary obstacles for the widespread adoption of deep learning-based Whole Slide Images (WSI) classification algorithms in clinical practice. Unlike few-shot learning…

计算机视觉与模式识别 · 计算机科学 2024-10-01 Kexue Fu , Xiaoyuan Luo , Linhao Qu , Shuo Wang , Ying Xiong , Ilias Maglogiannis , Longxiang Gao , Manning Wang

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

计算机视觉与模式识别 · 计算机科学 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

We address the challenging problem of whole slide image (WSI) classification. WSIs have very high resolutions and usually lack localized annotations. WSI classification can be cast as a multiple instance learning (MIL) problem when only…

计算机视觉与模式识别 · 计算机科学 2021-04-05 Bin Li , Yin Li , Kevin W. Eliceiri

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

计算机视觉与模式识别 · 计算机科学 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

计算机视觉与模式识别 · 计算机科学 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Digital histopathology whole slide images (WSIs) provide gigapixel-scale high-resolution images that are highly useful for disease diagnosis. However, digital histopathology image analysis faces significant challenges due to the limited…

计算机视觉与模式识别 · 计算机科学 2026-02-13 Bodong Zhang , Xiwen Li , Hamid Manoochehri , Xiaoya Tang , Deepika Sirohi , Beatrice S. Knudsen , Tolga Tasdizen

Recent advancements in computational pathology and artificial intelligence have significantly improved whole slide image (WSI) classification. However, the gigapixel resolution of WSIs and the scarcity of manual annotations present…

计算机视觉与模式识别 · 计算机科学 2024-08-26 Mingxi Ouyang , Yuqiu Fu , Renao Yan , ShanShan Shi , Xitong Ling , Lianghui Zhu , Yonghong He , Tian Guan

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Whole Slide Image (WSI) classification has very significant applications in clinical pathology, e.g., tumor identification and cancer diagnosis. Currently, most research attention is focused on Multiple Instance Learning (MIL) using static…

计算机视觉与模式识别 · 计算机科学 2025-04-17 Jiaxiang Gou , Luping Ji , Pei Liu , Mao Ye

Multiple instance learning (MIL) models have achieved remarkable success in analyzing whole slide images (WSIs) for disease classification problems. However, with regard to gigapixel WSI classification problems, current MIL models are often…

计算机视觉与模式识别 · 计算机科学 2023-12-14 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

Whole slide image (WSI) classification is a fundamental task for the diagnosis and treatment of diseases; but, curation of accurate labels is time-consuming and limits the application of fully-supervised methods. To address this, multiple…

计算机视觉与模式识别 · 计算机科学 2022-07-25 Philip Chikontwe , Soo Jeong Nam , Heounjeong Go , Meejeong Kim , Hyun Jung Sung , Sang Hyun Park

Whole Slide Image (WSI) classification relies on Multiple Instance Learning (MIL) with spatial patch features, yet existing methods struggle to capture global dependencies due to the immense size of WSIs and the local nature of patch…

计算机视觉与模式识别 · 计算机科学 2025-10-22 Anthony Bilic , Guangyu Sun , Ming Li , Md Sanzid Bin Hossain , Yu Tian , Wei Zhang , Laura Brattain , Dexter Hadley , Chen Chen

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

计算机视觉与模式识别 · 计算机科学 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang
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