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Artificial Intelligence is a field that lives many lives, and the term has come to encompass a motley collection of scientific and commercial endeavours. In this paper, I articulate the contours of a rather neglected but central scientific…

人工智能 · 计算机科学 2024-08-19 Dimitri Coelho Mollo

The increasing interest in complex networks research has been a consequence of several intrinsic features of this area, such as the generality of the approach to represent and model virtually any discrete system, and the incorporation of…

With the completion of human genome mapping, the focus of scientists seeking to explain the biological complexity of living systems is shifting from analyzing the individual components (such as a particular gene or biochemical reaction) to…

分子网络 · 定量生物学 2010-01-28 Sitabhra Sinha , T Jesan , Nivedita Chatterjee

When viewed at a certain coarse grain, the brain seems a relatively small dynamical system composed by a few dozen interacting areas, performing a number of stereotypical behaviors. It is known that, even relatively small dynamical systems…

神经元与认知 · 定量生物学 2015-06-26 Dante R. Chialvo

Insect production for food and feed presents a promising supplement to ensure food safety and address the adverse impacts of agriculture on climate and environment in the future. However, optimisation is required for insect production to…

计算机视觉与模式识别 · 计算机科学 2024-06-27 Min Ren , Yunlong Wang , Yuhao Zhu , Yongzhen Huang , Zhenan Sun , Qi Li , Tieniu Tan

In this work, we introduce a computational model for the study of the host-bacteria interaction and the influence of the intestinal microbiota on the behavior and feeding pattern of an individual. The model is based on digital entities,…

Whole-brain network analyses remain the vanguard in neuroimaging research, coming to prominence within the last decade. Network science approaches have facilitated these analyses and allowed examining the brain as an integrated system.…

应用统计 · 统计学 2015-05-04 Sean L. Simpson , Paul J. Laurienti

The features in high dimensional biomedical prediction problems are often well described with lower dimensional manifolds. An example is genes that are organised in smaller functional networks. The outcome can then be described with the…

统计方法学 · 统计学 2024-09-02 Magnus M. Münch , Mark A. van de Wiel , Aad W. van der Vaart , Carel F. W. Peeters

Fungal Biosynthetic Gene Clusters (BGCs) of secondary metabolites are clusters of genes capable of producing natural products, compounds that play an important role in the production of a wide variety of bioactive compounds, including…

基因组学 · 定量生物学 2020-03-31 Hayda Almeida , Adrian Tsang , Abdoulaye Baniré Diallo

Bio-inspired algorithms utilize natural processes such as evolution, swarm behavior, foraging, and plant growth to solve complex, nonlinear, high-dimensional optimization problems. However, a plethora of these algorithms require a more…

In recent years, substantial advancements have been achieved in understanding the diversity of the human virome and its intricate roles in human health and diseases. Despite this progress, the field of human virome research remains nascent,…

定量方法 · 定量生物学 2024-02-26 Yifan Wu , Yousong Peng

The aim of this paper is to give an overview of brain organoid computing, its characteristics, challenges, as well as possible advantages for future applications in the field of artificial intelligence. An important part is the extensive…

新兴技术 · 计算机科学 2025-11-04 Yannic Talavera , Bernd Ulmann

Graphs are quickly emerging as a leading abstraction for the representation of data. One important application domain originates from an emerging discipline called "connectomics". Connectomics studies the brain as a graph; vertices…

To further advance our understanding of the brain, new concepts and theories are needed. In particular, the ability of the brain to create information flows must be reconciled with its propensity for synchronization and mass action. The…

神经元与认知 · 定量生物学 2014-07-04 Emmanuelle Tognoli , J. A. Scott Kelso

Optimization plays an important role in tackling public health problems. Animal instincts can be used effectively to solve complex public health management issues by providing optimal or approximately optimal solutions to complicated…

神经与进化计算 · 计算机科学 2025-03-24 Eliuvish Cuicizion , Haowen Xu , Weng Kee Wong

Diverse subfields of neuroscience have enriched artificial intelligence for many decades. With recent advances in machine learning and artificial neural networks, many neuroscientists are partnering with AI researchers and machine learning…

神经元与认知 · 定量生物学 2019-12-03 Thomas Dean , Chaofei Fan , Francis E. Lewis , Megumi Sano

Human associated microbial communities exert tremendous influence over human health and disease. With modern metagenomic sequencing methods it is possible to follow the relative abundance of microbes in a community over time. These…

定量方法 · 定量生物学 2015-06-18 Charles K. Fisher , Pankaj Mehta

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

图像与视频处理 · 电气工程与系统科学 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Mammalian gut microbiomes are essential for host functions like digestion, immunity, and nutrient utilization. This study examines the gut microbiome of horses, donkeys, and their hybrids, mules and hinnies, to explore the role of…

基因组学 · 定量生物学 2024-07-09 Yihang Zhou

Recent multi-omic microbiome studies enable integrative analysis of microbes and metabolites, uncovering their associations with various host conditions. Such analyses require multivariate models capable of accounting for the complex…