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Longitudinal and time-to-event data are often analyzed in biomarker research to study the association between the longitudinal biomarker measurements and the event-time outcome, in which the longitudinal information contributes to the…

统计方法学 · 统计学 2025-09-09 Minzee Kim , Joel A. Dubin

It is often of interest to study the association between covariates and the cumulative incidence of a right-censored time-to-event outcome. When time-varying covariates are measured on a fixed discrete time scale, it is desirable to account…

统计方法学 · 统计学 2026-04-28 Hongxiang Qiu , Marco Carone , Alex Luedtke , Peter B. Gilbert

In many clinical contexts, estimating effects of treatment in time-to-event data is complicated not only by confounding, censoring, and heterogeneity, but also by the presence of a cured subpopulation in which the event of interest never…

统计方法学 · 统计学 2026-02-06 Yuqi Li , Quinn Lanners , Matthew M. Engelhard

Survival analysis is a critical tool for modeling time-to-event data. Recent deep learning-based models have reduced various modeling assumptions including proportional hazard and linearity. However, a persistent challenge remains in…

机器学习 · 计算机科学 2025-12-30 Maxmillan Ries , Sohan Seth

Causal inference methods are widely applied in the fields of medicine, policy, and economics. Central to these applications is the estimation of treatment effects to make decisions. Current methods make binary yes-or-no decisions based on…

机器学习 · 计算机科学 2020-04-24 Will Y. Zou , Smitha Shyam , Michael Mui , Mingshi Wang , Jan Pedersen , Zoubin Ghahramani

A common concern when a policymaker draws causal inferences from and makes decisions based on observational data is that the measured covariates are insufficiently rich to account for all sources of confounding, i.e., the standard no…

统计方法学 · 统计学 2023-10-25 Tao Shen , Yifan Cui

We introduce a novel modeling approach for time series imputation and forecasting, tailored to address the challenges often encountered in real-world data, such as irregular samples, missing data, or unaligned measurements from multiple…

In this work, we study the learning theory of reward modeling with pairwise comparison data using deep neural networks. We establish a novel non-asymptotic regret bound for deep reward estimators in a non-parametric setting, which depends…

机器学习 · 统计学 2025-05-13 Yuanhang Luo , Yeheng Ge , Ruijian Han , Guohao Shen

Utilizing clinical texts in survival analysis is difficult because they are largely unstructured. Current automatic extraction models fail to capture textual information comprehensively since their labels are limited in scope. Furthermore,…

计算与语言 · 计算机科学 2021-05-04 Hyun Gi Lee , Evan Sholle , Ashley Beecy , Subhi Al'Aref , Yifan Peng

We propose a procedure for imputing missing values of time-dependent covariates in a survival model using fully conditional specification. Specifically, we focus on imputing missing values of a longitudinal marker in joint modeling of the…

统计方法学 · 统计学 2024-03-29 Havi Murad , Nirit Agay , Rachel Dankner

Survival analysis aims at modeling the relationship between covariates and event occurrence with some untracked (censored) samples. In implementation, existing methods model the survival distribution with strong assumptions or in a discrete…

机器学习 · 计算机科学 2023-05-25 Yu Ling , Weimin Tan , Bo Yan

Interpreting critical variables involved in complex biological processes related to survival time can help understand prediction from survival models, evaluate treatment efficacy, and develop new therapies for patients. Currently, the…

机器学习 · 计算机科学 2022-10-03 Xinxing Wu , Chong Peng , Richard Charnigo , Qiang Cheng

We present an approach to adaptively utilize deep neural networks in order to reduce the evaluation time on new examples without loss of accuracy. Rather than attempting to redesign or approximate existing networks, we propose two schemes…

机器学习 · 计算机科学 2017-09-20 Tolga Bolukbasi , Joseph Wang , Ofer Dekel , Venkatesh Saligrama

We study the use of Temporal-Difference learning for estimating the structural parameters in dynamic discrete choice models. Our algorithms are based on the conditional choice probability approach but use functional approximations to…

计量经济学 · 经济学 2022-12-23 Karun Adusumilli , Dita Eckardt

The modeling of time-to-event data, also known as survival analysis, requires specialized methods that can deal with censoring and truncation, time-varying features and effects, and that extend to settings with multiple competing events.…

机器学习 · 统计学 2021-04-20 Andreas Bender , David Rügamer , Fabian Scheipl , Bernd Bischl

We introduce NeuralSurv, the first deep survival model to incorporate Bayesian uncertainty quantification. Our non-parametric, architecture-agnostic framework captures time-varying covariate-risk relationships in continuous time via a novel…

机器学习 · 计算机科学 2025-12-17 Mélodie Monod , Alessandro Micheli , Samir Bhatt

There is increasing interest in modeling high-dimensional longitudinal outcomes in applications such as developmental neuroimaging research. Growth curve model offers a useful tool to capture both the mean growth pattern across individuals,…

统计方法学 · 统计学 2023-05-26 Lu Wang , Xiang Lyu , Zhengwu Zhang , Lexin Li

Medical advances have increased cancer survival rates and the possibility of finding a cure. Hence, it is crucial to evaluate the impact of treatments both in terms of cure and prolongation of survival. To achieve this, we may use a Cox…

统计方法学 · 统计学 2024-12-31 Marta Cipriani , Marta Fiocco , Marco Alfò , Maria Quelhas , Eni Musta

When dealing with right-censored data, where some outcomes are missing due to a limited observation period, survival analysis -- known as time-to-event analysis -- focuses on predicting the time until an event of interest occurs. Multiple…

Multivariate time series have many applications, from healthcare and meteorology to life science. Although deep learning models have shown excellent predictive performance for time series, they have been criticised for being "black-boxes"…

机器学习 · 计算机科学 2024-05-06 Qiqi Su , Christos Kloukinas , Artur d'Avila Garcez