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Covariance matrix outcomes arise naturally in neuroimaging experiments to study brain functional connectivity. It is also of interest to understand how brain network organization varies with subject-level covariates. Existing covariance…

统计方法学 · 统计学 2026-05-08 Michelle Murphy Green , Xi Luo , Brian S. Caffo , Yi Zhao

The relationship between brain structure and function has been probed using a variety of approaches, but how the underlying structural connectivity of the human brain drives behavior is far from understood. To investigate the effect of…

神经元与认知 · 定量生物学 2018-11-15 Kanika Bansal , John D. Medaglia , Danielle S. Bassett , Jean M. Vettel , Sarah F. Muldoon

The general linear model (GLM) is a widely popular and convenient tool for estimating the functional brain response and identifying areas of significant activation during a task or stimulus. However, the classical GLM is based on a massive…

统计方法学 · 统计学 2021-10-28 Daniel Spencer , Yu , Yue , David Bolin , Sarah Ryan , Amanda F. Mejia

Decision making can be a complex process requiring the integration of several attributes of choice options. Understanding the neural processes underlying (uncertain) investment decisions is an important topic in neuroeconomics. We analyzed…

应用统计 · 统计学 2025-01-08 Piotr Majer , Peter N. C. Mohr , Hauke R. Heekeren , Wolfgang K. Härdle

In the quest for efficient neural network models for neural data interpretation and user intent classification in brain-computer interfaces (BCIs), learning meaningful sparse representations of the underlying neural subspaces is crucial.…

机器学习 · 计算机科学 2023-12-12 Hye-Bin Shin , Kang Yin , Seong-Whan Lee

Analysis of brain connectivity is important for understanding how information is processed by the brain. We propose a novel Bayesian vector autoregression (VAR) hierarchical model for analyzing brain connectivity in a resting-state fMRI…

应用统计 · 统计学 2021-12-09 Bertil Wegmann , Anders Lundquist , Anders Eklund , Mattias Villani

Longitudinal brain imaging data facilitate the monitoring of structural and functional alterations in individual brains across time, offering essential understanding of dynamic neurobiological mechanisms. Such data improve sensitivity for…

应用统计 · 统计学 2026-02-04 Zhentao Yu , Jiaqi Ding , Guorong Wu , Quefeng Li

Case vs control comparisons have been the classical approach to the study of neurological diseases. However, most patients will not fall cleanly into either group. Instead, clinicians will typically find patients that cannot be classified…

机器学习 · 统计学 2012-07-20 Iead Rezek , Christian Beckmann

Capturing dynamic spatiotemporal neural activity is essential for understanding large-scale brain mechanisms. Functional magnetic resonance imaging (fMRI) provides high-resolution cortical representations that form a strong basis for…

图像与视频处理 · 电气工程与系统科学 2026-04-01 Wanying Qu , Jianxiong Gao , Wei Wang , Yanwei Fu

Motivated by recent data analyses in biomedical imaging studies, we consider a class of image-on-scalar regression models for imaging responses and scalar predictors. We propose using flexible multivariate splines over triangulations to…

统计方法学 · 统计学 2021-06-04 Shan Yu , Guannan Wang , Li Wang , Lijian Yang

Detecting shared neural activity from functional magnetic resonance imaging (fMRI) across individuals exposed to the same stimulus can reveal synchronous brain responses, functional roles of regions, and potential clinical biomarkers.…

应用统计 · 统计学 2026-04-24 Spencer Wadsworth , Nabin Koirala , Nicole Landi , Ofer Harel

Cortical surface fMRI (cs-fMRI) has recently grown in popularity versus traditional volumetric fMRI, as it allows for more meaningful spatial smoothing and is more compatible with the common assumptions of isotropy and stationarity in…

应用统计 · 统计学 2017-06-06 Amanda Mejia , Yu Ryan Yue , David Bolin , Finn Lindren , Martin A. Lindquist

We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…

统计方法学 · 统计学 2020-05-26 Yin Song , Shufei Ge , Jiguo Cao , Liangliang Wang , Farouk S. Nathoo

Functional Magnetic Resonance Image (fMRI) is commonly employed to study human brain activity, since it offers insight into the relationship between functional fluctuations and human behavior. To enhance analysis and comprehension of brain…

人工智能 · 计算机科学 2025-02-04 Song Wang , Zhenyu Lei , Zhen Tan , Jiaqi Ding , Xinyu Zhao , Yushun Dong , Guorong Wu , Tianlong Chen , Chen Chen , Aiying Zhang , Jundong Li

Accurately monitoring cognitive load in real time is critical for Brain-Computer Interfaces (BCIs) that adapt to user engagement and support personalized learning. Electroencephalography (EEG) offers a non-invasive, cost-effective modality…

人机交互 · 计算机科学 2026-05-04 Deeksha M. Shama , Dimitra Emmanouilidou , Ivan J. Tashev

Background: Recent studies have indicated that functional connectivity is dynamic even during rest. A common approach to modeling the dynamic functional connectivity in whole-brain resting-state fMRI is to compute the correlation between…

神经元与认知 · 定量生物学 2019-11-05 Shih-Gu Huang , S. Balqis Samdin , Chee-Ming Ting , Hernando Ombao , Moo K. Chung

Population imaging studies rely upon good quality medical imagery before downstream image quantification. This study provides an automated approach to assess image quality from cardiovascular magnetic resonance (CMR) imaging at scale. We…

图像与视频处理 · 电气工程与系统科学 2025-10-28 Shahabedin Nabavi , Hossein Simchi , Mohsen Ebrahimi Moghaddam , Alejandro F. Frangi , Ahmad Ali Abin

In this paper, we introduce a new Bayesian approach for analyzing task fMRI data that simultaneously detects activation signatures and background connectivity. Our modeling involves a new hybrid tensor spatial-temporal basis strategy that…

应用统计 · 统计学 2023-12-04 Michelle F. Miranda , Jeffrey S. Morris

Human brain functional connectivity (FC) is often measured as the similarity of functional MRI responses across brain regions when a brain is either resting or performing a task. This paper aims to statistically analyze the dynamic nature…

计算机视觉与模式识别 · 计算机科学 2024-10-30 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

Understanding how the brain's complex nonlinear dynamics give rise to cognitive function remains a central challenge in neuroscience. While brain functional dynamics exhibits scale-free and multifractal properties across temporal scales,…

神经元与认知 · 定量生物学 2025-06-18 Sangyoon Bae , Junbeom Kwon , Shinjae Yoo , Jiook Cha