相关论文: Text2Cohort: Facilitating Intuitive Access to Biom…

The Genomic Data Commons (GDC) provides access to high quality, harmonized cancer genomics data through a unified curation and analysis platform centered around patient cohorts. While GDC users can interactively create complex cohorts…

Clinical trials are a critical process in the medical field for introducing new treatments and innovations. However, cohort selection for clinical trials is a time-consuming process that often requires manual review of patient text records…

The biomedical field relies heavily on concept linking in various areas such as literature mining, graph alignment, information retrieval, question-answering, data, and knowledge integration. Although large language models (LLMs) have made…

BACKGROUND: The amount of biomedical literature is rapidly growing and it is becoming increasingly difficult to keep manually curated knowledge bases and ontologies up-to-date. In this study we applied the word2vec deep learning toolkit to…

Background and Significance: Selecting cohorts for a clinical trial typically requires costly and time-consuming manual chart reviews resulting in poor participation. To help automate the process, National NLP Clinical Challenges (N2C2)…

Participant recruitment based on unstructured medical texts such as clinical notes and radiology reports has been a challenging yet important task for the cohort establishment in clinical research. Recently, Large Language Models (LLMs)…

Background and Objectives: Reproducibility is a major challenge in developing machine learning (ML)-based solutions in computational pathology (CompPath). The NCI Imaging Data Commons (IDC) provides >120 cancer image collections according…

Identifying cohorts of patients based on eligibility criteria such as medical conditions, procedures, and medication use is critical to recruitment for clinical trials. Such criteria are often most naturally described in free-text, using…

Breaking long documents into smaller segments is a fundamental challenge in information retrieval. Whether for search engines, question-answering systems, or retrieval-augmented generation (RAG), effective segmentation determines how well…

A crucial step in cohort studies is to extract the required cohort from one or more study datasets. This step is time-consuming, especially when a researcher is presented with a dataset that they have not previously worked with. When the…

Background: Widespread adoption of electronic health records (EHRs) has enabled secondary use of EHR data for clinical research and healthcare delivery. Natural language processing (NLP) techniques have shown promise in their capability to…

We propose In-Context Clustering (ICC), a flexible LLM-based procedure for clustering data from diverse distributions. Unlike traditional clustering algorithms constrained by predefined similarity measures, ICC flexibly captures complex…

Therapeutics machine learning is an emerging field with incredible opportunities for innovatiaon and impact. However, advancement in this field requires formulation of meaningful learning tasks and careful curation of datasets. Here, we…

Large Language Models (LLMs) exhibit In-Context Learning (ICL), which enables the model to perform new tasks conditioning only on the examples provided in the context without updating the model's weights. While ICL offers fast adaptation…

Invasive ductal carcinoma (IDC) is the most prevalent form of breast cancer, and early, accurate diagnosis is critical to improving patient survival rates by guiding treatment decisions. Combining medical expertise with artificial…

Entity extraction is a key technology for obtaining information from massive texts in natural language processing. The further interaction between them does not meet the standards of human reading comprehension, thus limiting the…

Knowledge graphs use nodes, relationships, and properties to represent arbitrarily complex data. When stored in a graph database, the Cypher query language enables efficient modeling and querying of knowledge graphs. However, using Cypher…

Tool calling allows large language models (LLMs) to interact with external systems like APIs, enabling applications in customer support, data analysis, and dynamic content generation. While recent benchmarks have advanced tool-use research,…

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

The growing demand for dynamic, user-centric data analysis and visualization is evident across domains like healthcare, finance, and research. Traditional visualization tools often fail to meet individual user needs due to their static and…