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We study analytically and numerically a model metabolic cycle composed of an arbitrary number of species of catalytically active particles. Each species converts a substrate into a product, the latter being used as the substrate by the next…

软凝聚态物质 · 物理学 2023-09-29 Vincent Ouazan-Reboul , Jaime Agudo-Canalejo , Ramin Golestanian

Mixtures of particles that interact through phoretic effects are known to aggregate if they belong to species that exhibit attractive self-interactions. We study self-organization in a model metabolic cycle composed of three species of…

软凝聚态物质 · 物理学 2023-09-29 Vincent Ouazan-Reboul , Ramin Golestanian , Jaime Agudo-Canalejo

Living systems contain intricate biochemical networks whose structure is closely related to their function and allows them to exhibit robust behavior in the presence of external stimuli. Such networks typically involve catalytic enzymes,…

生物物理 · 物理学 2025-10-27 Vincent Ouazan-Reboul , Ramin Golestanian , Jaime Agudo-Canalejo

A common feature of biological self-organization is how active agents communicate with each other or their environment via chemical signaling. Such communications, mediated by self-generated chemical gradients, have consequences for both…

Active particles with their characteristic feature of self-propulsion are regarded as the simplest models for motility in living systems. The accumulation of active particles in low activity regions has led to the general belief that…

软凝聚态物质 · 物理学 2021-05-26 Hidde D. Vuijk , Holger Merlitz , Michael Lang , Abhinav Sharma , Jens-Uwe Sommer

We investigate the stability properties of two different classes of metabolic cycles using a combination of analytical and computational methods. Using principles from structural kinetic modeling (SKM), we show that the stability of…

分子网络 · 定量生物学 2010-07-29 Ed Reznik , Daniel Segrè

In complex systems, groups of interacting objects may form prevalent and persistent spatiotemporal patterns, which we refer to as motifs. These motifs can exhibit features that reveal how individual objects interact with one another.…

生物物理 · 物理学 2025-12-12 Ying Chen Lim , Rakesh Das , Tetsuya Hiraiwa , N. Duane Loh

Collectives of actively-moving particles can spontaneously segregate into dilute and dense phases through a process known as motility-induced phase separation (MIPS). This captivating phenomenon is well-studied for randomly-moving particles…

软凝聚态物质 · 物理学 2026-03-04 Hongbo Zhao , Qiwei Yu , Andrej Košmrlj , Sujit S. Datta

Active matter systems comprise self-propelled particles that move on a substrate while leaving chemical trails that influence other particles through chemotaxis (e.g., slime-depositing bacteria). Orientational chemotaxis manifests as a…

软凝聚态物质 · 物理学 2025-12-11 Aymeric Lutier , Frédéric van Wijland , Jean-Baptiste Fournier

Self-propelled colloidal particles exhibit rich non-equilibrium phenomena and have promising applications in fields such as drug delivery and self-assembled active materials. Previous experimental and theoretical studies have shown that…

软凝聚态物质 · 物理学 2024-02-01 Zhiwei Peng , Raymond Kapral

We cast the metabolism of interacting cells within a statistical mechanics framework considering both, the actual phenotypic capacities of each cell and its interaction with its neighbors. Reaction fluxes will be the components of…

分子网络 · 定量生物学 2020-04-08 Jorge Fernandez-de-Cossio-Diaz , Roberto Mulet

Molecular building blocks interacting at the nanoscale organize spontaneously into stable mono- layers that display intriguing long-range ordering motifs on the surface of atomic substrates. The patterning process, if appropriately…

介观与纳米尺度物理 · 物理学 2011-02-18 Marta Balbás Gambra , Carsten Rohr , Kathrin Gruber , Bianca Hermann , Thomas Franosch

In the last years, a remarkable theoretical effort has been made in order to understand stability and complexity in ecological communities. The non-random structures of real ecological interaction networks has been recognized as one key…

种群与进化 · 定量生物学 2013-01-09 Samir Suweis , Jacopo Grilli , Amos Maritan

Chemotaxis, i.e. motion generated by chemical gradients, is a motility mode shared by many living species that has been developed by evolution to optimize certain biological processes such as foraging or immune response. In particular,…

软凝聚态物质 · 物理学 2023-05-24 Hugues Meyer , Heiko Rieger

Biomolecular condensates help organize the cell cytoplasm and nucleoplasm into spatial compartments with different chemical compositions. A key feature of such compositional patterning is the local enrichment of enzymatically active…

生物物理 · 物理学 2024-08-06 Andriy Goychuk , Leonardo Demarchi , Ivan Maryshev , Erwin Frey

We theoretically study mixtures of chemically-interacting particles, which produce or consume a chemical to which they are attracted or repelled, in the most general case of many coexisting species. We find a new class of active phase…

软凝聚态物质 · 物理学 2019-07-15 Jaime Agudo-Canalejo , Ramin Golestanian

The large scale behaviour of a population of cells that grow and interact through the concentration field of the chemicals they secrete is studied using dynamical renormalization group methods. The combination of the effective long-range…

细胞行为 · 定量生物学 2015-01-19 Anatolij Gelimson , Ramin Golestanian

Bacteria possess diverse mechanisms to regulate their motility in response to environmental and physiological signals, enabling them to navigate complex habitats and adapt their behavior. Among these mechanisms, interspecies recognition…

种群与进化 · 定量生物学 2025-12-01 Mattia Mattei , David Soriano Paños , Mahantesh Halappanavar , Alex Arenas

Active particle systems of interacting self-propelled particles offer a versatile framework for modeling complex systems. When employed to describe aspects of animal behavior, the complexity of animal movement and decision-making often…

生物物理 · 物理学 2025-01-09 Amir Haluts , Dan Gorbonos , Nir S. Gov

We demonstrate that active rotations in chemically signalling particles, such as autochemotactic {\it E. coli} close to walls, create a route for pattern formation based on a nonlinear yet deterministic instability mechanism. For slow…

软凝聚态物质 · 物理学 2016-08-19 Benno Liebchen , Michael E. Cates , Davide Marenduzzo
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