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Low-dose PET imaging is crucial for reducing patient radiation exposure but faces challenges like noise interference, reduced contrast, and difficulty in preserving physiological details. Existing methods often neglect both…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Mengxiao Geng , Ran Hong , Xiaoling Xu , Bingxuan Li , Qiegen Liu

Early diagnosis of Alzheimer's disease (AD) is critical for intervention before irreversible neurodegeneration occurs. Structural MRI (sMRI) is widely used for AD diagnosis, but conventional deep learning approaches primarily rely on…

图像与视频处理 · 电气工程与系统科学 2025-03-04 Shijia Zhang , Xiyu Ding , Brian Caffo , Junyu Chen , Cindy Zhang , Hadi Kharrazi , Zheyu Wang

Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have…

Positron Emission Tomography (PET) is a vital imaging modality widely used in clinical diagnosis and preclinical research but faces limitations in image resolution and signal-to-noise ratio due to inherent physical degradation factors.…

图像与视频处理 · 电气工程与系统科学 2024-11-11 Boxiao Yu , Kuang Gong

Accurate quantification of cerebral blood flow (CBF) is essential for the diagnosis and assessment of a wide range of neurological diseases. Positron emission tomography (PET) with radiolabeled water (15O-water) is considered the…

计算机视觉与模式识别 · 计算机科学 2022-11-23 Ramy Hussein , David Shin , Moss Zhao , Jia Guo , Guido Davidzon , Michael Moseley , Greg Zaharchuk

Motivation: Alzheimer's Disease hallmarks include amyloid-beta deposits and brain atrophy, detectable via PET and MRI scans, respectively. PET is expensive, invasive and exposes patients to ionizing radiation. MRI is cheaper, non-invasive,…

图像与视频处理 · 电气工程与系统科学 2024-05-06 Fernando Vega , Abdoljalil Addeh , M. Ethan MacDonald

This study introduces a novel framework for joint reconstruction of the activity and the attenuation (JRAA) in positron emission tomography (PET) using diffusion posterior sampling (DPS). By leveraging diffusion models (DMs), this approach…

Diffusion models have shown great promise in medical image denoising and reconstruction, but their application to Positron Emission Tomography (PET) imaging remains limited by tracer-specific contrast variability and high computational…

图像与视频处理 · 电气工程与系统科学 2026-02-03 Fumio Hashimoto , Kuang Gong

Positron Emission Tomography (PET) is now regarded as the gold standard for the diagnosis of Alzheimer's Disease (AD). However, PET imaging can be prohibitive in terms of cost and planning, and is also among the imaging techniques with the…

Positron Emission Tomography (PET) is a functional imaging modality that enables the visualization of biochemical and physiological processes across various tissues. Recently, deep learning (DL)-based methods have demonstrated significant…

图像与视频处理 · 电气工程与系统科学 2026-01-16 Yiran Sun , Osama Mawlawi

Background: Alzheimer's disease (AD) diagnosis heavily relies on amyloid-beta positron emission tomography (Abeta-PET), which is limited by high cost and limited accessibility. This study explores whether Abeta-PET spatial patterns can be…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Zhengjie Zhang , Xiaoxie Mao , Qihao Guo , Shaoting Zhang , Qi Huang , Mu Zhou , Fang Xie , Mianxin Liu

Alzheimer's Disease (AD) is the most common form of dementia and often difficult to diagnose due to the multifactorial etiology of dementia. Recent works on neuroimaging-based computer-aided diagnosis with deep neural networks (DNNs) showed…

图像与视频处理 · 电气工程与系统科学 2022-07-06 Marla Narazani , Ignacio Sarasua , Sebastian Pölsterl , Aldana Lizarraga , Igor Yakushev , Christian Wachinger

Artificial Intelligence (AI) based image analysis has an immense potential to support diagnostic histopathology, including cancer diagnostics. However, developing supervised AI methods requires large-scale annotated datasets. A potentially…

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…

Due to various physical degradation factors and limited counts received, PET image quality needs further improvements. The denoising diffusion probabilistic models (DDPM) are distribution learning-based models, which try to transform a…

图像与视频处理 · 电气工程与系统科学 2022-09-15 Kuang Gong , Keith A. Johnson , Georges El Fakhri , Quanzheng Li , Tinsu Pan

We propose a robust alignment technique for Standard Fundus Images (SFIs) and Ultra-Widefield Fundus Images (UWFIs), which are challenging to align due to differences in scale, appearance, and the scarcity of distinctive features. Our…

计算机视觉与模式识别 · 计算机科学 2026-04-14 Kanggeon Lee , Soochahn Lee , Kyoung Mu Lee

We introduce the Pyramid Diffusion Model (PDM), a novel architecture designed for ultra-high-resolution image synthesis. PDM utilizes a pyramid latent representation, providing a broader design space that enables more flexible, structured,…

计算机视觉与模式识别 · 计算机科学 2024-03-20 Jiajie Yang

Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…

图像与视频处理 · 电气工程与系统科学 2024-11-26 Yunxiang Li , Hua-Chieh Shao , Xiaoxue Qian , You Zhang

Deep learning has significantly advanced PET image re-construction, achieving remarkable improvements in image quality through direct training on sinogram or image data. Traditional methods often utilize masks for inpainting tasks, but…

计算机视觉与模式识别 · 计算机科学 2025-03-12 Bin Huang , Binzhong He , Yanhan Chen , Zhili Liu , Xinyue Wang , Binxuan Li , Qiegen Liu