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Meta-analyses statistically aggregate the findings of different randomized controlled trials (RCTs) to assess treatment effectiveness. Because this yields robust estimates of treatment effectiveness, results from meta-analyses are…

计算与语言 · 计算机科学 2024-07-26 Hye Sun Yun , David Pogrebitskiy , Iain J. Marshall , Byron C. Wallace

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

计算与语言 · 计算机科学 2024-11-18 Diya Li , Asim Kadav , Aijing Gao , Rui Li , Richard Bourgon

The best evidence concerning comparative treatment effectiveness comes from clinical trials, the results of which are reported in unstructured articles. Medical experts must manually extract information from articles to inform…

计算与语言 · 计算机科学 2022-01-11 Benjamin E. Nye , Jay DeYoung , Eric Lehman , Ani Nenkova , Iain J. Marshall , Byron C. Wallace

Systematic reviews are crucial for synthesizing scientific evidence but remain labor-intensive, especially when extracting detailed methodological information. Large language models (LLMs) offer potential for automating methodological…

计算与语言 · 计算机科学 2025-10-14 Wenqing Zhang , Trang Nguyen , Elizabeth A. Stuart , Yiqun T. Chen

Europe's healthcare systems require enhanced interoperability and digitalization, driving a demand for innovative solutions to process legacy clinical data. This paper presents the results of our project, which aims to leverage Large…

计算与语言 · 计算机科学 2025-07-09 Aynur Guluzade , Naguib Heiba , Zeyd Boukhers , Florim Hamiti , Jahid Hasan Polash , Yehya Mohamad , Carlos A Velasco

Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

Evidence-based medicine, the practice in which healthcare professionals refer to the best available evidence when making decisions, forms the foundation of modern healthcare. However, it relies on labour-intensive systematic reviews, where…

计算与语言 · 计算机科学 2021-12-13 Jetsun Whitton , Anthony Hunter

This paper describes a rapid feasibility study of using GPT-4, a large language model (LLM), to (semi)automate data extraction in systematic reviews. Despite the recent surge of interest in LLMs there is still a lack of understanding of how…

Large language models (LLMs) are increasingly used in statistical research and applications. However,they are also notorious for unreliable or biased information. Here, we explore whether LLMs can be used to improve the precision of…

应用统计 · 统计学 2026-05-29 Jaylin Lowe , Adam Sales , Johann A. Gagnon-Bartsch

Large language models (LLMs) have demonstrated impressive abilities in generating unstructured natural language according to instructions. However, their performance can be inconsistent when tasked with producing text that adheres to…

计算与语言 · 计算机科学 2024-02-22 Yinghao Li , Rampi Ramprasad , Chao Zhang

Systematic reviews and meta-analyses rely on converting narrative articles into structured, numerically grounded study records. Despite rapid advances in large language models (LLMs), it remains unclear whether they can meet the structural…

计算与语言 · 计算机科学 2026-02-12 Zhiyin Tan , Jennifer D'Souza

Intelligently extracting and linking complex scientific information from unstructured text is a challenging endeavor particularly for those inexperienced with natural language processing. Here, we present a simple sequence-to-sequence…

Failure is common in clinical trials since the successful failures presented in negative results always indicate the ways that should not be taken. In this paper, we proposed an automated approach to extracting positive and negative…

信息检索 · 计算机科学 2022-12-08 Xuanyu Shi , Shiyao Xie , Wenjia Wang , Ting Chen , Jian Du

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

计算与语言 · 计算机科学 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Large language models (LLMs) are increasingly used to extract structured information from free-text clinical records, but prior work often focuses on single tasks, limited models, and English-language reports. We evaluated 15 open-weight…

Systematic reviews in medicine play a critical role in evidence-based decision-making by aggregating findings from multiple studies. A central bottleneck in automating this process is extracting numeric evidence and determining study-level…

人工智能 · 计算机科学 2026-01-26 Massimiliano Pronesti , Michela Lorandi , Paul Flanagan , Oisin Redmond , Anya Belz , Yufang Hou

Randomized experiments or randomized controlled trials (RCTs) are gold standards for causal inference, yet cost and sample-size constraints limit power. We introduce CALM (Causal Analysis leveraging Language Models), a statistical framework…

统计方法学 · 统计学 2025-12-09 Xinrui Ruan , Xinwei Ma , Yingfei Wang , Waverly Wei , Jingshen Wang

Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a…

We present a simple approach for automatically extracting the number of subjects involved in randomised controlled trials (RCT). Our approach first applies a set of rule-based techniques to extract candidate study sizes from the abstracts…

人工智能 · 计算机科学 2016-06-24 Abeed Sarker

Offline evaluation of search systems depends on test collections. These benchmarks provide the researchers with a corpus of documents, topics and relevance judgements indicating which documents are relevant for each topic. While test…

信息检索 · 计算机科学 2025-07-23 David Otero , Javier Parapar , Álvaro Barreiro
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