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A Deep Autoencoder based content retrieval algorithm is proposed for prediction and differentiation of cancer types based on the presence of epigenetic patterns of DNA methylation identified in genetic regions known as CpG islands. The…

定量方法 · 定量生物学 2018-10-08 Mohammed Khwaja , Melpomeni Kalofonou , Chris Toumazou

The spatial distributions of different types of cells could reveal a cancer cell growth pattern, its relationships with the tumor microenvironment and the immune response of the body, all of which represent key hallmarks of cancer. However,…

计算机视觉与模式识别 · 计算机科学 2018-09-28 Shidan Wang , Tao Wang , Lin Yang , Faliu Yi , Xin Luo , Yikun Yang , Adi Gazdar , Junya Fujimoto , Ignacio I. Wistuba , Bo Yao , ShinYi Lin , Yang Xie , Yousheng Mao , Guanghua Xiao

Breast cancer is the most common cancer in women worldwide. The most common screening technology is mammography. To reduce the cost and workload of radiologists, we propose a computer aided detection approach for classifying and localizing…

计算机视觉与模式识别 · 计算机科学 2018-03-07 Pengcheng Xi , Chang Shu , Rafik Goubran

This study introduces a novel and accurate approach to breast cancer classification using histopathology images. It systematically compares leading Convolutional Neural Network (CNN) models across varying image datasets, identifies their…

计算机视觉与模式识别 · 计算机科学 2024-10-07 Gary Murphy , Raghubir Singh

Deep learning for regression tasks on medical imaging data has shown promising results. However, compared to other approaches, their power is strongly linked to the dataset size. In this study, we evaluate 3D-convolutional neural networks…

计算机视觉与模式识别 · 计算机科学 2018-11-13 Yannick Suter , Alain Jungo , Michael Rebsamen , Urspeter Knecht , Evelyn Herrmann , Roland Wiest , Mauricio Reyes

Early and accurate detection through Pap smear analysis is critical to improving patient outcomes and reducing mortality of Cervical cancer. State-of-the-art (SOTA) Convolutional Neural Networks (CNNs) require substantial computational…

组织与器官 · 定量生物学 2025-09-23 Saifuddin Sagor , Md Taimur Ahad , Faruk Ahmed , Rokonozzaman Ayon , Sanzida Parvin

Breast cancer molecular subtypes classification plays an import role to sort patients with divergent prognosis. The biomarkers used are Estrogen Receptor (ER), Progesterone Receptor (PR), HER2, and Ki67. Based on these biomarkers expression…

机器学习 · 计算机科学 2023-10-24 Matheus del-Valle , Emerson Soares Bernardes , Denise Maria Zezell

Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…

图像与视频处理 · 电气工程与系统科学 2025-08-22 Jinliang Yu , Mingduo Xie , Yue Wang , Tianfan Fu , Xianglai Xu , Jiajun Wang

Based on digital pathology slice scanning technology, artificial intelligence algorithms represented by deep learning have achieved remarkable results in the field of computational pathology. Compared to other medical images, pathology…

图像与视频处理 · 电气工程与系统科学 2023-11-17 Hao Quan , Xingyu Li , Weixing Chen , Qun Bai , Mingchen Zou , Ruijie Yang , Tingting Zheng , Ruiqun Qi , Xinghua Gao , Xiaoyu Cui

Breast cancer is one of the leading causes of death among women across the globe. It is difficult to treat if detected at advanced stages, however, early detection can significantly increase chances of survival and improves lives of…

图像与视频处理 · 电气工程与系统科学 2023-08-17 Unaiza Sajid , Rizwan Ahmed Khan , Shahid Munir Shah , Sheeraz Arif

Efficient and precise classification of histological cell nuclei is of utmost importance due to its potential applications in the field of medical image analysis. It would facilitate the medical practitioners to better understand and…

计算机视觉与模式识别 · 计算机科学 2019-11-19 S H Shabbeer Basha , Soumen Ghosh , Kancharagunta Kishan Babu , Shiv Ram Dubey , Viswanath Pulabaigari , Snehasis Mukherjee

Colorectal cancer remains a major global health concern, with early detection being pivotal for improving patient outcomes. In this study, we leveraged high throughput methylation profiling of cellfree DNA to identify and validate…

基因组学 · 定量生物学 2025-05-19 Kartavya Mathur , Shipra Jain , Nisha Bajiya , Nishant Kumar , Gajendra P. S. Raghava

Pancreatic cancer will soon be the second leading cause of cancer-related death in Western society. Imaging techniques such as CT, MRI and ultrasound typically help providing the initial diagnosis, but histopathological assessment is still…

图像与视频处理 · 电气工程与系统科学 2022-01-26 Pierpaolo Vendittelli , Esther M. M. Smeets , Geert Litjens

Artificial intelligence (AI) models have been developed for predicting clinically relevant biomarkers, including microsatellite instability (MSI), for colorectal cancers (CRC). However, the current deep-learning networks are data-hungry and…

定量方法 · 定量生物学 2024-12-24 Bangwei Guo , Xingyu Li , Jitendra Jonnagaddala , Hong Zhang , Xu Steven Xu

Computer assisted diagnosis in digital pathology is becoming ubiquitous as it can provide more efficient and objective healthcare diagnostics. Recent advances have shown that the convolutional Neural Network (CNN) architectures, a…

图像与视频处理 · 电气工程与系统科学 2022-01-05 Sruthi Krishna , Suganthi S. S , Shivsubramani Krishnamoorthy , Arnav Bhavsar

Accurate and robust drug response prediction is of utmost importance in precision medicine. Although many models have been developed to utilize the representations of drugs and cancer cell lines for predicting cancer drug responses (CDR),…

定量方法 · 定量生物学 2023-11-22 Xiaoqiong Xia , Chaoyu Zhu , Yuqi Shan , Fan Zhong , Lei Liu

Convolutional neural networks (CNNs) have been recently used for a variety of histology image analysis. However, availability of a large dataset is a major prerequisite for training a CNN which limits its use by the computational pathology…

计算机视觉与模式识别 · 计算机科学 2018-03-07 Ruqayya Awan , Navid Alemi Koohbanani , Muhammad Shaban , Anna Lisowska , Nasir Rajpoot

Digital pathology (DP) is a new research area which falls under the broad umbrella of health informatics. Owing to its potential for major public health impact, in recent years DP has been attracting much research attention. Nevertheless, a…

图像与视频处理 · 电气工程与系统科学 2019-03-12 Xingzhi Yue , Neofytos Dimitriou , Ognjen Arandjelovic

Deep transfer learning using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has shown strong predictive power in characterization of breast lesions. However, pretrained convolutional neural networks (CNNs) require 2D inputs,…

医学物理 · 物理学 2019-11-11 Qiyuan Hu , Heather M. Whitney , Maryellen L. Giger

We suggest that deep learning can be used for pre-screening cancer by analyzing demographic and anthropometric information of patients, as well as biological markers obtained from routine blood samples and relative risks obtained from…

机器学习 · 统计学 2023-02-07 Rolando Gonzales Martinez , Daan-Max van Dongen