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We consider machine-learning-based thyroid-malignancy prediction from cytopathology whole-slide images (WSI). Multiple instance learning (MIL) approaches, typically used for the analysis of WSIs, divide the image (bag) into patches…

While multiple instance learning (MIL) has shown to be a promising approach for histopathological whole slide image (WSI) analysis, its reliance on permutation invariance significantly limits its capacity to effectively uncover semantic…

图像与视频处理 · 电气工程与系统科学 2025-07-14 Xiwen Chen , Peijie Qiu , Wenhui Zhu , Hao Wang , Huayu Li , Xuanzhao Dong , Xiaotong Sun , Xiaobing Yu , Yalin Wang , Abolfazl Razi , Aristeidis Sotiras

Learning representations for individual instances when only bag-level labels are available is a fundamental challenge in multiple instance learning (MIL). Recent works have shown promising results using contrastive self-supervised learning…

计算机视觉与模式识别 · 计算机科学 2023-07-13 Kangning Liu , Weicheng Zhu , Yiqiu Shen , Sheng Liu , Narges Razavian , Krzysztof J. Geras , Carlos Fernandez-Granda

Annotating large-scale LiDAR point clouds for 3D semantic segmentation is costly and time-consuming, which motivates the use of semi-supervised learning (SemiSL). Standard LiDAR SemiSL methods typically adopt a two-step training paradigm,…

计算机视觉与模式识别 · 计算机科学 2026-05-19 Bin Yang , Alexandru Paul Condurache

Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…

计算机视觉与模式识别 · 计算机科学 2025-07-03 Ali Mammadov , Loïc Le Folgoc , Guillaume Hocquet , Pietro Gori

Multiple Instance Learning (MIL) has advanced WSI analysis but struggles with the complexity and heterogeneity of WSIs. Existing MIL methods face challenges in aggregating diverse patch information into robust WSI representations. While…

计算机视觉与模式识别 · 计算机科学 2025-07-28 Beidi Zhao , SangMook Kim , Hao Chen , Chen Zhou , Zu-hua Gao , Gang Wang , Xiaoxiao Li

Multi-Instance Learning (MIL) is pivotal for analyzing complex, weakly labeled datasets, such as whole-slide images (WSIs) in computational pathology, where bags comprise unordered collections of instances with sparse diagnostic relevance.…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Yuedi Zhang , Zhixiang Xia , Guosheng Yin , Bin Liu

Multiple instance learning (MIL) is the standard approach for whole-slide image (WSI) classification and survival prediction, where attention-based models ag gregate patch features into slide-level predictions. These models treat attention…

计算机视觉与模式识别 · 计算机科学 2026-05-19 Xiangyu Li , Ran Su

Weakly supervised image segmentation approaches in the literature usually achieve high segmentation performance using tight bounding box supervision and decrease the performance greatly when supervised by loose bounding boxes. However,…

计算机视觉与模式识别 · 计算机科学 2023-01-31 Juan Wang , Bin Xia

Fine-grained classification of whole slide images (WSIs) is essential in precision oncology, enabling precise cancer diagnosis and personalized treatment strategies. The core of this task involves distinguishing subtle morphological…

计算机视觉与模式识别 · 计算机科学 2025-04-07 Cheng Jin , Luyang Luo , Huangjing Lin , Jun Hou , Hao Chen

Semi-weakly supervised semantic segmentation (SWSSS) aims to train a model to identify objects in images based on a small number of images with pixel-level labels, and many more images with only image-level labels. Most existing SWSSS…

计算机视觉与模式识别 · 计算机科学 2022-05-04 Wonho Bae , Junhyug Noh , Milad Jalali Asadabadi , Danica J. Sutherland

We present Self-Organizing Visual Prototypes (SOP), a new training technique for unsupervised visual feature learning. Unlike existing prototypical self-supervised learning (SSL) methods that rely on a single prototype to encode all…

计算机视觉与模式识别 · 计算机科学 2025-05-29 Thalles Silva , Helio Pedrini , Adín Ramírez Rivera

Whole slide images (WSI) are microscopy images of stained tissue slides routinely prepared for diagnosis and treatment selection in medical practice. WSI are very large (gigapixel size) and complex (made of up to millions of cells). The…

计算机视觉与模式识别 · 计算机科学 2022-12-08 Tristan Lazard , Marvin Lerousseau , Etienne Decencière , Thomas Walter

Semi-Supervised Instance Segmentation (SSIS) aims to leverage an amount of unlabeled data during training. Previous frameworks primarily utilized the RGB information of unlabeled images to generate pseudo-labels. However, such a mechanism…

计算机视觉与模式识别 · 计算机科学 2024-06-26 Xin Chen , Jie Hu , Xiawu Zheng , Jianghang Lin , Liujuan Cao , Rongrong Ji

In the field of computational histopathology, both whole slide images (WSIs) and diagnostic captions provide valuable insights for making diagnostic decisions. However, aligning WSIs with diagnostic captions presents a significant…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Qifeng Zhou , Wenliang Zhong , Yuzhi Guo , Michael Xiao , Hehuan Ma , Junzhou Huang

This paper presents a weakly supervised image segmentation method that adopts tight bounding box annotations. It proposes generalized multiple instance learning (MIL) and smooth maximum approximation to integrate the bounding box tightness…

计算机视觉与模式识别 · 计算机科学 2021-10-25 Juan Wang , Bin Xia

The segmentation and automatic identification of histological regions of diagnostic interest offer a valuable aid to pathologists. However, segmentation methods are hampered by the difficulty of obtaining pixel-level annotations, which are…

图像与视频处理 · 电气工程与系统科学 2023-02-02 Pushpak Pati , Guillaume Jaume , Zeineb Ayadi , Kevin Thandiackal , Behzad Bozorgtabar , Maria Gabrani , Orcun Goksel

Multi-instance learning (MIL) deals with objects represented as bags of instances and can predict instance labels from bag-level supervision. However, significant performance gaps exist between instance-level MIL algorithms and supervised…

机器学习 · 计算机科学 2022-10-06 Weijia Zhang , Xuanhui Zhang , Han-Wen Deng , Min-Ling Zhang

Pseudo-labeling is significant for semi-supervised instance segmentation, which generates instance masks and classes from unannotated images for subsequent training. However, in existing pipelines, pseudo-labels that contain valuable…

计算机视觉与模式识别 · 计算机科学 2023-08-11 Jie Hu , Chen Chen , Liujuan Cao , Shengchuan Zhang , Annan Shu , Guannan Jiang , Rongrong Ji

Acquiring annotations for whole slide images (WSIs)-based deep learning tasks, such as creating tissue segmentation masks or detecting mitotic figures, is a laborious process due to the extensive image size and the significant manual work…

计算机视觉与模式识别 · 计算机科学 2024-07-10 Jingna Qiu , Marc Aubreville , Frauke Wilm , Mathias Öttl , Jonas Utz , Maja Schlereth , Katharina Breininger