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Analyzing the health status of patients based on Electronic Health Records (EHR) is a fundamental research problem in medical informatics. The presence of extensive missing values in EHR makes it challenging for deep neural networks (DNNs)…

机器学习 · 计算机科学 2025-03-14 Weibin Liao , Yinghao Zhu , Zhongji Zhang , Yuhang Wang , Zixiang Wang , Xu Chu , Yasha Wang , Liantao Ma

Real-time monitoring in modern medical research introduces functional longitudinal data, characterized by continuous-time measurements of outcomes, treatments, and confounders. This complexity leads to uncountably infinite…

统计方法学 · 统计学 2025-08-15 Andrew Ying

In many machine learning applications, we are faced with incomplete datasets. In the literature, missing data imputation techniques have been mostly concerned with filling missing values. However, the existence of missing values is…

机器学习 · 计算机科学 2020-09-07 Mohammad Kachuee , Kimmo Karkkainen , Orpaz Goldstein , Sajad Darabi , Majid Sarrafzadeh

Missing data are ubiquitous in empirical databases, yet statistical analyses typically require complete data matrices. Multiple imputation offers a principled solution for filling these gaps. This study evaluates the performance of several…

统计计算 · 统计学 2026-02-05 Enzo Porto Brasil

Missing data are ubiquitous in the era of big data and, if inadequately handled, are known to lead to biased findings and have deleterious impact on data-driven decision makings. To mitigate its impact, many missing value imputation methods…

机器学习 · 计算机科学 2021-10-26 Yiliang Zhang , Qi Long

Missing data theory deals with the statistical methods in the occurrence of missing data. Missing data occurs when some values are not stored or observed for variables of interest. However, most of the statistical theory assumes that data…

统计方法学 · 统计学 2021-10-26 Luis Alejandro Masmela-Caita , Thais Paiva Galletti , Marcos Oliveira Prates

Inference is the task of drawing conclusions about unobserved variables given observations of related variables. Applications range from identifying diseases from symptoms to classifying economic regimes from price movements. Unfortunately,…

Missing data is a common challenge across scientific disciplines. Current imputation methods require the availability of individual data to impute missing values. Often, however, missingness requires using external data for the imputation.…

统计方法学 · 统计学 2024-10-07 Robert Thiesmeier , Matteo Bottai , Nicola Orsini

Instrumental variable methods provide useful tools for inferring causal effects in the presence of unmeasured confounding. To apply these methods with large-scale data sets, a major challenge is to find valid instruments from a possibly…

统计方法学 · 统计学 2024-09-24 Xinyi Zhang , Linbo Wang , Stanislav Volgushev , Dehan Kong

Utilizing covariate information has been a powerful approach to improve the efficiency and accuracy for causal inference, which support massive amount of randomized experiments run on data-driven enterprises. However, state-of-art…

统计方法学 · 统计学 2023-11-06 Yuhang Wu , Jinghai He , Zeyu Zheng

Many scientific questions in biomedical, environmental, and psychological research involve understanding the effects of multiple factors on outcomes. While factorial experiments are ideal for this purpose, randomized controlled treatment…

统计方法学 · 统计学 2025-12-03 Ruoqi Yu , Peng Ding

Quantum machine learning is emerging as a promising application of quantum computing due to its distinct way of encoding and processing data. It is believed that large-scale quantum machine learning demonstrates substantial advantages over…

量子物理 · 物理学 2025-01-15 Kiwmann Hwang , Hyang-Tag Lim , Yong-Su Kim , Daniel K. Park , Yosep Kim

Minimizing the Mean Squared Error (MSE) is a key objective in machine learning and is commonly used for imputing missing values. While this approach provides accurate point estimates, it introduces systematic biases in downstream analyses.…

机器学习 · 统计学 2026-05-06 Stef van Buuren

Missing data is inevitable in longitudinal clinical trials. Conventionally, the missing at random assumption is assumed to handle missingness, which however is unverifiable empirically. Thus, sensitivity analysis is critically important to…

统计方法学 · 统计学 2022-03-18 Siyi Liu , Shu Yang , Yilong Zhang , Guanghan , Liu

Most recent network failure diagnosis systems focused on data center networks where complex measurement systems can be deployed to derive routing information and ensure network coverage in order to achieve accurate and fast fault…

网络与互联网体系结构 · 计算机科学 2022-07-06 Yufeng Xin , Shih-Wen Fu , Anirban Mandal , Ryan Tanaka , Mats Rynge , Karan Vahi , Ewa Deelman

Incomplete Multi-view Clustering (IMC) has emerged as a significant challenge in multi-view learning. A predominant line for IMC is data imputation; however, indiscriminate imputation can result in unreliable content. Recently, researchers…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Cai Xu , Jinlong Liu , Yilin Zhang , Ziyu Guan , Wei Zhao , Xiaofei He

We demonstrate the application of a quantum feature extraction method to enhance multi-class image classification for space applications. By harnessing the dynamics of many-body spin Hamiltonians, the method generates expressive quantum…

Clinical trials with longitudinal outcomes typically include missing data due to missed assessments or structural missingness of outcomes after intercurrent events handled with a hypothetical strategy. Approaches based on Bayesian random…

统计方法学 · 统计学 2022-03-21 Marcel Wolbers , Alessandro Noci , Paul Delmar , Craig Gower-Page , Sean Yiu , Jonathan W. Bartlett

Imputing missing values is common practice in label-free quantitative proteomics. Imputation aims at replacing a missing value with a user-defined one. However, the imputation itself may not be optimally considered downstream of the…

统计方法学 · 统计学 2022-09-08 Marie Chion , Christine Carapito , Frédéric Bertrand

Modern multi-modal and multi-site data frequently suffer from blockwise missingness, where subsets of features are missing for groups of individuals, creating complex patterns that challenge standard inference methods. Existing approaches…

统计方法学 · 统计学 2025-09-18 Sarah Zhao , Emmanuel Candès