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Elastic light scattering by mature red blood cells (RBCs) was theoretically and experimentally analyzed with the discrete dipole approximation (DDA) and the scanning flow cytometry (SFC), respectively. SFC permits measurement of angular…

Morphology of cardiovascular tissue is influenced by the unsteady behavior of the blood flow and vice versa. Therefore, the pathogenesis of several cardiovascular diseases is directly affected by the blood-flow dynamics. Understanding flow…

Timely diagnostics of microcirculatory system abnormalities which are the most severe diabetic complications, is a significant problem of modern health care. Functional abnormalities manifest themselves earlier than the structural one and…

组织与器官 · 定量生物学 2024-11-27 Irina Mizeva , Elena Zharkikh , Victor Dremin , Evgeny Zherebtsov , Irina Makovik , Elena Potapova , Andrey Dunaev

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with…

医学物理 · 物理学 2021-08-27 Mohammad Sarabian , Hessam Babaee , Kaveh Laksari

Intrasaccular flow disruptors treat cerebral aneurysms by diverting the blood flow from the aneurysm sac. Residual flow into the sac after the intervention is a failure that could be due to the use of an undersized device, or to vascular…

Multiplexed immuno-fluorescence tissue imaging, allowing simultaneous detection of molecular properties of cells, is an essential tool for characterizing the complex cellular mechanisms in translational research and clinical practice. New…

Objective: Blood transfusions, crucial in managing anemia and coagulopathy in ICU settings, require accurate prediction for effective resource allocation and patient risk assessment. However, existing clinical decision support systems have…

Diffuse correlation spectroscopy (DCS) is an emerging noninvasive technique that measures the tissue blood flow, by using near-infrared coherent point-source illumination to detect spectral changes. While machine learning has demonstrated…

机器学习 · 计算机科学 2024-02-02 Xi Chen , Xingda Li

Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…

图像与视频处理 · 电气工程与系统科学 2021-11-08 Virender Ranga , Shivam Gupta , Priyansh Agrawal , Jyoti Meena

An exhaustive description of the dynamics under shear flow of a large number of red blood cells in dilute regime is proposed, which highlights and takes into account the dispersion in cell properties within a given blood sample.…

生物物理 · 物理学 2019-02-11 Christophe Minetti , Vassanti Audemar , Thomas Podgorski , Gwennou Coupier

Background: Cardiovascular diseases (CVDs) are the leading cause of death globally. The use of artificial intelligence (AI) methods - in particular, deep learning (DL) - has been on the rise lately for the analysis of different CVD-related…

The plasma membrane of human red blood cells consists of a lipid bilayer attached to a regular network of underlying cytoskeletal polymers. We model this system at a dynamic coarse-grained level, treating the bilayer as an elastic sheet and…

亚细胞过程 · 定量生物学 2009-11-13 Rui Zhang , Frank L. H. Brown

Machine learning (ML) and deep learning (DL) models have been employed to significantly improve analyses of medical imagery, with these approaches used to enhance the accuracy of prediction and classification. Model predictions and…

图像与视频处理 · 电气工程与系统科学 2023-08-22 Rabia Asghar , Sanjay Kumar , Paul Hynds , Arslan Shaukat

Patient-specific therapies require that cells be manufactured in multiple batches of small volumes, making it a challenge for conventional modes of quality control. The added complexity of inherent variability (even within batches)…

生物物理 · 物理学 2018-04-17 Derrick Yong , Ahmad Amirul Abdul Rahim , Jesslyn Ong , May Win Naing

Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…

软凝聚态物质 · 物理学 2015-03-17 Florian Janoschek , Federico Toschi , Jens Harting

We present experimental evidence of multiple blood flow configurations in a relatively simple microfluidic network under constant inlet conditions. We provide evidence of multistability and unsteady dynamics and find good agreement with a…

流体动力学 · 物理学 2024-10-08 Mathieu Alonzo , Nathaniel J. Karst , Thomas Podgorski , John B. Geddes , Gwennou Coupier

Reflectance Confocal Microscopy (RCM) is a non-invasive imaging technique used in biomedical research and clinical dermatology. It provides virtual high-resolution images of the skin and superficial tissues, reducing the need for physical…

图像与视频处理 · 电气工程与系统科学 2024-04-26 Hong-Jun Yoon , Chris Keum , Alexander Witkowski , Joanna Ludzik , Tracy Petrie , Heidi A. Hanson , Sancy A. Leachman

Designing intelligent microrobots that can autonomously navigate and perform instructed routines in blood vessels, a complex and crowded environment with obstacles including dense cells, different flow patterns and diverse vascular…

软凝聚态物质 · 物理学 2021-03-25 Yuguang Yang , Michael A. Bevan , Bo Li

Leukemia (blood cancer) is an unusual spread of White Blood Cells or Leukocytes (WBCs) in the bone marrow and blood. Pathologists can diagnose leukemia by looking at a person's blood sample under a microscope. They identify and categorize…

计算机视觉与模式识别 · 计算机科学 2023-03-13 Mohammad Zolfaghari , Hedieh Sajedi

Recent advancements in Artificial Intelligence (AI) have significantly influenced the field of Cardiovascular Disease (CVD) analysis, particularly in image-based diagnostics. Our paper presents an extensive review of AI applications in…

图像与视频处理 · 电气工程与系统科学 2025-12-12 Xin Wang , Mingcheng Hu , Connie W. Tsao , Hongtu Zhu
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