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Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

The hydrodynamic theory of active nematics has been often used to describe the spatio-temporal dynamics of cell flows and motile topological defects within soft confluent tissues. Those theories, however, often rely on the assumption that…

软凝聚态物质 · 物理学 2023-08-15 Ioannis Hadjifrangiskou , Liam J. Ruske , Julia M. Yeomans

We derive and numerically solve a surface active nematodynamics model. We validate the numerical approach on a sphere and analyse the influence of hydrodynamics on the oscillatory motion of topological defects. For ellipsoidal surfaces the…

软凝聚态物质 · 物理学 2022-09-07 Michael Nestler , Axel Voigt

We consider the dynamics of active nematics droplets on flat surfaces, based on the continuum hydrodynamic theory. We investigate a wide range of dynamical regimes as a function of the activity and droplet size on surfaces characterized by…

软凝聚态物质 · 物理学 2023-09-11 Rodrigo C. V. Coelho , Hélio R. J. C. Figueiredo , Margarida M. Telo da Gama

Inspired by recent experiments that highlight the role of nematic defects in the morphogenesis of epithelial tissues, we develop a minimal framework to study the dynamics of an active curved surface driven by its nematic texture. Allowing…

软凝聚态物质 · 物理学 2022-09-14 Farzan Vafa , L. Mahadevan

Active nematics are out-of-equilibrium systems in which energy injection at the microscale drives emergent collective behaviors, from spontaneous flows to active turbulence. While the dynamics of these systems have been extensively studied,…

软凝聚态物质 · 物理学 2025-04-15 Ahmet Umut Akduman , Yusuf Sariyar , Giuseppe Negro , Livio Nicola Carenza

Shape transformations of epithelial tissues in three dimensions, which are crucial for embryonic development or in vitro organoid growth, can result from active forces generated within the cytoskeleton of the epithelial cells. How the…

生物物理 · 物理学 2024-12-23 Diana Khoromskaia , Guillaume Salbreux

Active nematics are microscopically driven liquid crystals that exhibit dynamical steady states characterized by the creation and annihilation of topological defects. Motivated by experimental realizations of such systems made of biopolymer…

软凝聚态物质 · 物理学 2018-09-05 Abhijeet Joshi , Elias Putzig , Aparna Baskaran , Michael Hagan

The structure and dynamics of important biological quasi-two-dimensional systems, ranging from cytoskeletal gels to tissues, are controlled by nematic order, flow, defects and activity. Continuum hydrodynamic descriptions combined with…

生物物理 · 物理学 2024-12-03 Waleed Mirza , Alejandro Torres-Sánchez , Guillermo Vilanova , Marino Arroyo

Point-like motile topological defects control the universal dynamics of diverse two-dimensional active nematics ranging from shaken granular rods to cellular monolayers. A comparable understanding in higher dimensions has yet to emerge. We…

Biological cells are able to generate intricate structures and respond to external stimuli, sculpting their membrane from within. Simplified biomimetic systems can aid in understanding the principles which govern these shape changes and…

Topological defects in active liquid crystals can be confined by introducing gradients of activity. Here, we examine the dynamical behavior of two defects confined by a sharp gradient of activity that separates an active circular region and…

软凝聚态物质 · 物理学 2021-06-16 Ali Mozaffari , Rui Zhang , Noe Atzin , Juan J. de Pablo

Morphogenesis emerges from dynamic feedback among geometry, mechanics, and chemistry; however, disentangling these contributions in living systems remains challenging. Here, we focus on the interplay between geometry and mechanics by…

We study emergent dynamics in a viscous drop subject to interfacial nematic activity. Using hydrodynamic simulations, we show how the interplay of nematodynamics, activity-driven flows and surface deformations gives rise to a sequence of…

软凝聚态物质 · 物理学 2024-04-19 Mohammadhossein Firouznia , David Saintillan

Topology transcends boundaries that conventionally delineate physical, biological and engineering sciences. Our ability to mathematically describe topology, combined with our access to precision tracking and manipulation approaches, has…

生物物理 · 物理学 2021-01-01 Anupam Sengupta

Continuum models of active nematic gels have proved successful to describe a number of biological systems consisting of a population of rodlike motile subunits in a fluid environment. However, in order to get a thorough understanding of the…

软凝聚态物质 · 物理学 2023-05-03 Stefano Turzi

With exquisite precision and reproducibility, cells orchestrate the cooperative action of thousands of nanometer-sized molecular motors to carry out mechanical tasks at much larger length scales, such as cell motility, division and…

软凝聚态物质 · 物理学 2013-01-08 Tim Sanchez , Daniel T. N. Chen , Stephen J. DeCamp , Michael Heymann , Zvonimir Dogic

The dynamics of active smectic liquid crystals confined on a spherical surface is explored through an active phase field crystal model. Starting from an initially randomly perturbed isotropic phase, several types of topological defects are…

软凝聚态物质 · 物理学 2025-03-11 Michael Nestler , Simon Praetorius , Zhi-Feng Huang , Hartmut Löwen , Axel Voigt

We consider active nematodynamics on deformable surfaces. Based on a thermodynamically consistent surface Beris-Edwards model we add nematic activity and focus on the emerging additional coupling mechanism between the nematic field, the…

软凝聚态物质 · 物理学 2024-05-24 Ingo Nitschke , Axel Voigt

There is now growing evidence of the emergence and biological functionality of liquid crystal features, including nematic order and topological defects, in cellular tissues. However, how such features that intrinsically rely on particle…

软凝聚态物质 · 物理学 2019-02-06 Romain Mueller , Julia Yeomans , Amin Doostmohammadi
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