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Brain function relies on a precisely coordinated and dynamic balance between the functional integration and segregation of distinct neural systems. Characterizing the way in which neural systems reconfigure their interactions to give rise…

神经元与认知 · 定量生物学 2021-01-28 Lingbin Bian , Tiangang Cui , B. T. Thomas Yeo , Alex Fornito , Adeel Razi , Jonathan Keith

We introduce techniques for analysing the structure of quantum states of many-body localized (MBL) spin chains by identifying correlation clusters from pairwise correlations. These techniques proceed by interpreting pairwise correlations in…

无序系统与神经网络 · 物理学 2022-02-16 Kévin Hémery , Frank Pollmann , Adam Smith

Functional magnetic resonance imaging (fMRI) enables non-invasive brain disorder classification by capturing blood-oxygen-level-dependent (BOLD) signals. However, most existing methods rely on functional connectivity (FC) via Pearson…

计算机视觉与模式识别 · 计算机科学 2026-02-10 Guoqi Yu , Xiaowei Hu , Angelica I. Aviles-Rivero , Anqi Qiu , Shujun Wang

We investigate two recently proposed multivariate time series analysis techniques that aim at detecting phase synchronization clusters in spatially extended, nonstationary systems with regard to field applications. The starting point of…

数据分析、统计与概率 · 物理学 2010-03-15 Stephan Bialonski , Klaus Lehnertz

Multivariate Time-Series (MTS) clustering is crucial for signal processing and data analysis. Although deep learning approaches, particularly those leveraging Contrastive Learning (CL), are prominent for MTS representation, existing…

机器学习 · 计算机科学 2026-01-13 Zexi Tan , Tao Xie , Haoyi Xiao , Baoyao Yang , Yuzhu Ji , An Zeng , Xiang Zhang , Yiqun Zhang

This study integrates causal inference, graph analysis, temporal complexity measures, and machine learning to examine whether individual symptom trajectories can reveal meaningful diagnostic patterns. Testing on a longitudinal dataset of…

应用统计 · 统计学 2025-07-22 Eleonora Vitanza , Pietro DeLellis , Chiara Mocenni , Manuel Ruiz Marin

Objective: An electroencephalogram (EEG)-based brain-computer interface (BCI) enables direct communication between the human brain and a computer. Due to individual differences and non-stationarity of EEG signals, such BCIs usually require…

人机交互 · 计算机科学 2024-12-11 Siyang Li , Ziwei Wang , Hanbin Luo , Lieyun Ding , Dongrui Wu

Currently, data-driven discovery in biological sciences resides in finding segmentation strategies in multivariate data that produce sensible descriptions of the data. Clustering is but one of several approaches and sometimes falls short…

定量方法 · 定量生物学 2022-08-12 Richard Tjörnhammar

With rapid development of techniques to measure brain activity and structure, statistical methods for analyzing modern brain-imaging play an important role in the advancement of science. Imaging data that measure brain function are usually…

统计方法学 · 统计学 2023-01-05 Haoyi Fu , Lu Tang , Ori Rosen , Alison E. Hipwell , Theodore J. Huppert , Robert T. Krafty

Physiologic signals have properties across multiple spatial and temporal scales, which can be shown by the complexity-analysis of the coarse-grained physiologic signals by scaling techniques such as the multiscale. Unfortunately, the…

机器学习 · 计算机科学 2020-11-10 Jiawei Yang , Jeffrey M. Hausdorff

This work proposes a two-step method to enhance disease risk estimation in small areas by integrating spatiotemporal cluster detection within a Bayesian hierarchical spatiotemporal model. First, we introduce an efficient…

统计方法学 · 统计学 2026-04-14 G. Santafé , A. Adin , M. D. Ugarte

We formulate a novel technique for the detection of functional clusters in discrete event data. The advantage of this algorithm is that no prior knowledge of the number of functional groups is needed, as our procedure progressively combines…

神经元与认知 · 定量生物学 2015-05-13 S. Feldt , J. Waddell , V. L. Hetrick , J. D. Berke , M. Zochowski

Querying causal effects from time-series data is important across various fields, including healthcare, economics, climate science, and epidemiology. However, this task becomes complex in the existence of time-varying latent confounders,…

机器学习 · 计算机科学 2024-11-28 Debo Cheng , Ziqi Xu , Jiuyong Li , Lin Liu , Thuc duy Le , Xudong Guo , Shichao Zhang

Early-stage scoliosis is often difficult to detect, particularly in adolescents, where delayed diagnosis can lead to serious health issues. Traditional X-ray-based methods carry radiation risks and rely heavily on clinical expertise,…

计算机视觉与模式识别 · 计算机科学 2025-10-07 Haiqing Li , Yuzhi Guo , Feng Jiang , Thao M. Dang , Hehuan Ma , Qifeng Zhou , Jean Gao , Junzhou Huang

We consider the problem of analyzing multivariate time series collected on multiple subjects, with the goal of identifying groups of subjects exhibiting similar trends in their recorded measurements over time as well as time-varying groups…

In healthcare, patient risk stratification models are often learned using time-series data extracted from electronic health records. When extracting data for a clinical prediction task, several formulations exist, depending on how one…

机器学习 · 计算机科学 2018-12-03 Eli Sherman , Hitinder Gurm , Ulysses Balis , Scott Owens , Jenna Wiens

Most approaches for assessing causality in complex dynamical systems fail when the interactions between variables are inherently non-linear and non-stationary. Here we introduce Temporal Autoencoders for Causal Inference (TACI), a…

机器学习 · 计算机科学 2024-06-06 Josuan Calderon , Gordon J. Berman

In the realm of precision medicine, effective patient stratification and disease subtyping demand innovative methodologies tailored for multi-omics data. Clustering techniques applied to multi-omics data have become instrumental in…

机器学习 · 计算机科学 2024-01-30 Bastian Pfeifer , Christel Sirocchi , Marcus D. Bloice , Markus Kreuzthaler , Martin Urschler

Improving the future of healthcare starts by better understanding the current actual practices in hospital settings. This motivates the objective of discovering typical care pathways from patient data. Revealing typical care pathways can be…

机器学习 · 计算机科学 2024-12-20 Thomas Guyet , Pierre Pinson , Enoal Gesny

Supervised causal learning has shown promise in causal discovery, yet it often struggles with generalization across diverse interventional settings, particularly when intervention targets are unknown. To address this, we propose TICL…

机器学习 · 计算机科学 2026-02-24 Wei Chen , Rui Ding , Bojun Huang , Yang Zhang , Qiang Fu , Yuxuan Liang , Han Shi , Dongmei Zhang