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Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

医学物理 · 物理学 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Low-dose CT (LDCT) protocols reduce radiation exposure but increase image noise, compromising diagnostic confidence. Diffusion-based generative models have shown promise for LDCT denoising by learning image priors and performing iterative…

计算机视觉与模式识别 · 计算机科学 2025-08-14 Tomás de la Sotta , José M. Saavedra , Héctor Henríquez , Violeta Chang , Aline Xavier

Sparse-view sampling in dual-energy computed tomography (DECT) significantly reduces radiation dose and increases imaging speed, yet is highly prone to artifacts. Although diffusion models have demonstrated potential in effectively handling…

图像与视频处理 · 电气工程与系统科学 2025-04-11 Zini Chen , Yao Xiao , Junyan Zhang , Shaoyu Wang , Liu Shi , Qiegen Liu

Generative models have demonstrated significant success in anomaly detection and segmentation over the past decade. Recently, diffusion models have emerged as a powerful alternative, outperforming previous approaches such as GANs and VAEs.…

计算机视觉与模式识别 · 计算机科学 2026-04-22 Mehrdad Moradi , Marco Grasso , Bianca Maria Colosimo , Kamran Paynabar

Cone-beam computed tomography (CBCT) is widely used in image-guided radiotherapy. Reconstructing CBCTs from limited-angle acquisitions (LA-CBCT) is highly desired for improved imaging efficiency, dose reduction, and better mechanical…

医学物理 · 物理学 2024-04-10 Jiacheng Xie , Hua-Chieh Shao , Yunxiang Li , You Zhang

Diffuse optical breast imaging utilizes near-infrared (NIR) light propagation through tissues to assess the optical properties of tissue for the identification of abnormal tissue. This optical imaging approach is sensitive, cost-effective,…

医学物理 · 物理学 2017-11-22 Wenxiang Cong , Xavier Intes , Ge Wang

Breast cancer is the most frequently diagnosed human cancer in the United States at present. Early detection is crucial for its successful treatment. X-ray mammography and digital breast tomosynthesis are currently the main methods for…

Sparse-view Computed Tomography (CT) image reconstruction is a promising approach to reduce radiation exposure, but it inevitably leads to image degradation. Although diffusion model-based approaches are computationally expensive and suffer…

图像与视频处理 · 电气工程与系统科学 2024-03-15 Hanyu Chen , Zhixiu Hao , Lin Guo , Liying Xiao

A major challenge in X-ray computed tomography (CT) is reducing radiation dose while maintaining high quality of reconstructed images. To reduce the radiation dose, one can reduce the number of projection views (sparse-view CT); however, it…

机器学习 · 统计学 2019-09-17 Xuehang Zheng , Il Yong Chun , Zhipeng Li , Yong Long , Jeffrey A. Fessler

Diffusion Posterior Sampling(DPS) methodology is a novel framework that permits nonlinear CT reconstruction by integrating a diffusion prior and an analytic physical system model, allowing for one-time training for different applications.…

图像与视频处理 · 电气工程与系统科学 2024-07-19 Xiao Jiang , Shudong Li , Peiqing Teng , Grace Gang , J. Webster Stayman

Low-dose computed tomography (LDCT) plays a vital role in clinical applications by mitigating radiation risks. Nevertheless, reducing radiation doses significantly degrades image quality. Concurrently, common deep learning methods demand…

图像与视频处理 · 电气工程与系统科学 2024-05-28 Wenhao Zhang , Bin Huang , Shuyue Chen , Xiaoling Xu , Weiwen Wu , Qiegen Liu

Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…

图像与视频处理 · 电气工程与系统科学 2023-07-17 Xuan Liu , Yaoqin Xie , Jun Cheng , Songhui Diao , Shan Tan , Xiaokun Liang

Dynamic contrast-enhanced (DCE) MRI is essential for breast cancer diagnosis and treatment. However, its reliance on contrast agents introduces safety concerns, contraindications, increased cost, and workflow complexity. To this end, we…

Diffusion models face significant challenges when employed for large-scale medical image reconstruction in real practice such as 3D Computed Tomography (CT). Due to the demanding memory, time, and data requirements, it is difficult to train…

计算机视觉与模式识别 · 计算机科学 2025-09-24 Bowen Song , Jason Hu , Zhaoxu Luo , Jeffrey A. Fessler , Liyue Shen

Recently, diffusion models (DM) have been applied in magnetic resonance imaging (MRI) super-resolution (SR) reconstruction, exhibiting impressive performance, especially with regard to detailed reconstruction. However, the current DM-based…

计算机视觉与模式识别 · 计算机科学 2024-04-09 Guangyuan Li , Chen Rao , Juncheng Mo , Zhanjie Zhang , Wei Xing , Lei Zhao

This research presents a novel framework for the compression and decompression of medical images utilizing the Latent Diffusion Model (LDM). The LDM represents advancement over the denoising diffusion probabilistic model (DDPM) with a…

图像与视频处理 · 电气工程与系统科学 2023-10-10 InChan Hwang , MinJae Woo

Breast cancer screening relies heavily on mammography, where the craniocaudal (CC) and mediolateral oblique (MLO) views provide complementary information for diagnosis. However, many datasets lack complete paired views, limiting the…

Limited-angle and sparse-view computed tomography (LACT and SVCT) are crucial for expanding the scope of X-ray CT applications. However, they face challenges due to incomplete data acquisition, resulting in diverse artifacts in the…

图像与视频处理 · 电气工程与系统科学 2024-07-22 Chenhe Du , Xiyue Lin , Qing Wu , Xuanyu Tian , Ying Su , Zhe Luo , Rui Zheng , Yang Chen , Hongjiang Wei , S. Kevin Zhou , Jingyi Yu , Yuyao Zhang

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

医学物理 · 物理学 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

Background: Dual-energy imaging on cone-beam CT (CBCT) scanners has great potential in different clinical applications, including image-guided surgery and adaptive proton therapy. However, the clinical practice of dual-energy CBCT (DE-CBCT)…