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Mammalian brains operate in a very special surrounding: to survive they have to react quickly and effectively to the pool of stimuli patterns previously recognized as danger. Many learning tasks often encountered by living organisms involve…

Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…

神经元与认知 · 定量生物学 2022-04-01 Braden A. W. Brinkman , Han Yan , Arianna Maffei , Il Memming Park , Alfredo Fontanini , Jin Wang , Giancarlo La Camera

The study of balanced networks of excitatory and inhibitory neurons has led to several open questions. On the one hand it is yet unclear whether the asynchronous state observed in the brain is autonomously generated, or if it results from…

神经元与认知 · 定量生物学 2016-09-22 Rodrigo Echeveste , Claudius Gros

Deep feedforward and recurrent rate-based neural networks have become successful functional models of the brain, but they neglect obvious biological details such as spikes and Dale's law. Here we argue that these details are crucial in…

神经元与认知 · 定量生物学 2023-12-29 William F. Podlaski , Christian K. Machens

Neurons and other excitable systems can release energy suddenly given a small stimulus. Excitability has recently drawn increasing interest in optics, as it is key to realize all-optical artificial neurons enabling speed-of-light…

Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…

神经元与认知 · 定量生物学 2011-09-21 Choongseok Park , Leonid L. Rubchinsky

Population-wide oscillations are ubiquitously observed in mesoscopic signals of cortical activity. In these network states a global oscillatory cycle modulates the propensity of neurons to fire. Synchronous activation of neurons has been…

神经元与认知 · 定量生物学 2017-07-04 Tobias Kühn , Moritz Helias

Cortical circuits exhibit intricate recurrent architectures that are remarkably similar across different brain areas. Such stereotyped structure suggests the existence of common computational principles. However, such principles have…

神经元与认知 · 定量生物学 2018-01-04 Rui Ponte Costa , Yannis M. Assael , Brendan Shillingford , Nando de Freitas , Tim P. Vogels

A neural correlate of parametric working memory is a stimulus specific rise in neuron firing rate that persists long after the stimulus is removed. Network models with local excitation and broad inhibition support persistent neural…

神经元与认知 · 定量生物学 2013-10-15 Zachary P. Kilpatrick , Bard Ermentrout , Brent Doiron

A simple model that replicates the dynamics of spiking and spiking-bursting activity of real biological neurons is proposed. The model is a two-dimensional map which contains one fast and one slow variable. The mechanisms behind generation…

混沌动力学 · 物理学 2009-11-07 Nikolai F. Rulkov

Network of neurons in the brain apply - unlike processors in our current generation of computer hardware - an event-based processing strategy, where short pulses (spikes) are emitted sparsely by neurons to signal the occurrence of an event…

神经与进化计算 · 计算机科学 2014-12-19 Zeno Jonke , Stefan Habenschuss , Wolfgang Maass

Networks of interconnected neurons communicating through spiking signals offer the bedrock of neural computations. Our brains spiking neural networks have the computational capacity to achieve complex pattern recognition and cognitive…

神经与进化计算 · 计算机科学 2024-12-06 Naresh Ravichandran , Anders Lansner , Pawel Herman

We study the collective dynamics of a Leaky Integrate and Fire network in which precise relative phase relationship of spikes among neurons are stored, as attractors of the dynamics, and selectively replayed at differentctime scales. Using…

神经元与认知 · 定量生物学 2012-10-26 Silvia Scarpetta , Ferdinando Giacco

A fundamental problem in neuroscience is understanding how working memory -- the ability to store information at intermediate timescales, like 10s of seconds -- is implemented in realistic neuronal networks. The most likely candidate…

神经元与认知 · 定量生物学 2015-05-13 Yasser Roudi , Peter E. Latham

Being permanently confronted with an uncertain world, brains have faced evolutionary pressure to represent this uncertainty in order to respond appropriately. Often, this requires visiting multiple interpretations of the available…

Processing sequential inputs is a fundamental brain function, underlying tasks such as sensory perception, language, and motor control. A challenge in sequence processing is to represent not only the order of events, but also their precise…

神经元与认知 · 定量生物学 2026-05-22 Melissa Lober , Younes Bouhadjar , Markus Diesmann , Tom Tetzlaff

Cortical neurons are subject to sustained and irregular synaptic activity which causes important fluctuations of the membrane potential (Vm). We review here different methods to characterize this activity and its impact on spike generation.…

Short-term memory in the brain cannot in general be explained the way long-term memory can -- as a gradual modification of synaptic weights -- since it takes place too quickly. Theories based on some form of cellular bistability, however,…

神经元与认知 · 定量生物学 2013-01-31 Samuel Johnson , J. Marro , Joaquín J. Torres

We examine whether a single biophysical cortical circuit model can explain both spiking and perceptual variability. We consider perceptual rivalry, which provides a window into intrinsic neural processing since neural activity in some brain…

神经元与认知 · 定量生物学 2018-11-20 Benjamin P Cohen , Carson C Chow , Shashaank Vattikuti

Biologically-inspired Spiking Neural Networks (SNNs), processing information using discrete-time events known as spikes rather than continuous values, have garnered significant attention due to their hardware-friendly and energy-efficient…

神经与进化计算 · 计算机科学 2023-08-21 Bin Lei , Sheng Lin , Pei-Hung Lin , Chunhua Liao , Caiwen Ding