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Prostate cancer (PCa) is one of the most commonly diagnosed cancer and one of the leading causes of death among men, with almost 1.41 million new cases and around 375,000 deaths in 2020. Artificial Intelligence algorithms have had a huge…

The aggressiveness of prostate cancer, the most common cancer in men worldwide, is primarily assessed based on histopathological data using the Gleason scoring system. While artificial intelligence (AI) has shown promise in accurately…

We propose a Deep learning-based weak label learning method for analyzing whole slide images (WSIs) of Hematoxylin and Eosin (H&E) stained tumor tissue not requiring pixel-level or tile-level annotations using Self-supervised pre-training…

图像与视频处理 · 电气工程与系统科学 2023-06-29 Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

A large labeled dataset is a key to the success of supervised deep learning, but for medical image segmentation, it is highly challenging to obtain sufficient annotated images for model training. In many scenarios, unannotated images are…

计算机视觉与模式识别 · 计算机科学 2021-07-13 Hao Zheng , Jun Han , Hongxiao Wang , Lin Yang , Zhuo Zhao , Chaoli Wang , Danny Z. Chen

Ovarian cancer is the most lethal cancer of the female reproductive organs. There are $5$ major histological subtypes of epithelial ovarian cancer, each with distinct morphological, genetic, and clinical features. Currently, these…

Self-supervised learning (SSL) has emerged as a powerful paradigm for Chest X-ray (CXR) analysis under limited annotations. Yet, existing SSL strategies remain suboptimal for medical imaging. Masked image modeling allocates substantial…

计算机视觉与模式识别 · 计算机科学 2026-03-25 Wangyu Feng , Shawn Young , Lijian Xu

Pan-cancer classification using transcriptomic (RNA-Seq) data can inform tumor subtyping and therapy selection, but is challenging due to extremely high dimensionality and limited sample sizes. In this study, we propose a novel deep…

基因组学 · 定量生物学 2025-08-06 Vinil Polepalli

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to…

计算机视觉与模式识别 · 计算机科学 2020-11-02 Krishna Chaitanya , Ertunc Erdil , Neerav Karani , Ender Konukoglu

Automatic and accurate Gleason grading of histopathology tissue slides is crucial for prostate cancer diagnosis, treatment, and prognosis. Usually, histopathology tissue slides from different institutions show heterogeneous appearances…

计算机视觉与模式识别 · 计算机科学 2018-06-08 Jian Ren , Ilker Hacihaliloglu , Eric A. Singer , David J. Foran , Xin Qi

The coronavirus pandemic has been going on since the year 2019, and the trend is still not abating. Therefore, it is particularly important to classify medical CT scans to assist in medical diagnosis. At present, Supervised Deep Learning…

图像与视频处理 · 电气工程与系统科学 2022-10-12 Jiashu Xu , Sergii Stirenko

Deep learning-based analysis of high-frequency, high-resolution micro-ultrasound data shows great promise for prostate cancer detection. Previous approaches to analysis of ultrasound data largely follow a supervised learning paradigm.…

图像与视频处理 · 电气工程与系统科学 2022-11-02 Paul F. R. Wilson , Mahdi Gilany , Amoon Jamzad , Fahimeh Fooladgar , Minh Nguyen Nhat To , Brian Wodlinger , Purang Abolmaesumi , Parvin Mousavi

Self-supervised learning (SSL) is a machine learning approach where the data itself provides supervision, eliminating the need for external labels. The model is forced to learn about the data structure or context by solving a pretext task.…

计算机视觉与模式识别 · 计算机科学 2024-07-19 Markus Marks , Manuel Knott , Neehar Kondapaneni , Elijah Cole , Thijs Defraeye , Fernando Perez-Cruz , Pietro Perona

Worldwide, prostate cancer is one of the main cancers affecting men. The final diagnosis of prostate cancer is based on the visual detection of Gleason patterns in prostate biopsy by pathologists. Computer-aided-diagnosis systems allow to…

计算机视觉与模式识别 · 计算机科学 2020-05-26 Amartya Kalapahar , Julio Silva-Rodríguez , Adrián Colomer , Fernando López-Mir , Valery Naranjo

We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…

计算机视觉与模式识别 · 计算机科学 2023-09-08 Alexandre Tiard , Alex Wong , David Joon Ho , Yangchao Wu , Eliram Nof , Alvin C. Goh , Stefano Soatto , Saad Nadeem

Deep Learning models have been successfully utilized to extract clinically actionable insights from routinely available histology data. Generally, these models require annotations performed by clinicians, which are scarce and costly to…

机器学习 · 计算机科学 2024-03-13 Tim Lenz , Omar S. M. El Nahhas , Marta Ligero , Jakob Nikolas Kather

Supervised deep learning methods have achieved considerable success in medical image analysis, owing to the availability of large-scale and well-annotated datasets. However, creating such datasets for whole slide images (WSIs) in…

计算机视觉与模式识别 · 计算机科学 2024-06-10 Hao Wang , Euijoon Ahn , Jinman Kim

Self-supervised learning (SSL) has emerged as a promising paradigm for addressing the annotation bottleneck in medical imaging by learning representations from unlabeled data. However, its effectiveness depends heavily on the design of the…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Chathura Wimalasiri

This paper presents a novel convolutional neural network (CNN) based image compression framework via scalable auto-encoder (SAE). Specifically, our SAE based deep image codec consists of hierarchical coding layers, each of which is an…

多媒体 · 计算机科学 2019-04-02 Chuanmin Jia , Zhaoyi Liu , Yao Wang , Siwei Ma , Wen Gao

Deep learning can promote the mammography-based computer-aided diagnosis (CAD) for breast cancers, but it generally suffers from the small sample size problem. Self-supervised learning (SSL) has shown its effectiveness in medical image…

图像与视频处理 · 电气工程与系统科学 2021-08-31 Ronglin Gong , Jun Wang , Jun Shi

Histopathological assessments, including surgical resection and core needle biopsy, are the standard procedures in the diagnosis of the prostate cancer. Current interpretation of the histopathology images includes the determination of the…

计算机视觉与模式识别 · 计算机科学 2017-05-12 Naiyun Zhou , Andrey Fedorov , Fiona Fennessy , Ron Kikinis , Yi Gao