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We present a foundation modeling framework that leverages deep learning to uncover latent genetic signatures across the hematopoietic hierarchy. Our approach trains a fully connected autoencoder on multipotent progenitor cells, reducing…

机器学习 · 计算机科学 2025-03-27 Gabriel Bo , Justin Gu , Christopher Sun

Histopathology images contain essential information for medical diagnosis and prognosis of cancerous disease. Segmentation of glands in histopathology images is a primary step for analysis and diagnosis of an unhealthy patient. Due to the…

图像与视频处理 · 电气工程与系统科学 2019-09-04 Safiyeh Rezaei , Ali Emami , Hamidreza Zarrabi , Shima Rafiei , Kayvan Najarian , Nader Karimi , Shadrokh Samavi , S. M. Reza Soroushmehr

Background and objective: Cell-level pathological image analysis requires working with extremely small image patches (40x40 pixels), far below standard ImageNet resolutions. It remains unclear whether modern deep learning architectures and…

计算机视觉与模式识别 · 计算机科学 2026-03-05 Hiroki Kagiyama , Toru Nagasaka , Yukari Adachi , Takaaki Tachibana , Ryota Ito , Mitsugu Fujita , Kimihiro Yamashita , Yoshihiro Kakeji

To train a robust deep learning model, one usually needs a balanced set of categories in the training data. The data acquired in a medical domain, however, frequently contains an abundance of healthy patients, versus a small variety of…

图像与视频处理 · 电气工程与系统科学 2020-03-09 Jevgenij Gamper , Brandon Chan , Yee Wah Tsang , David Snead , Nasir Rajpoot

Machine learning has endless applications in the health care industry. White blood cell classification is one of the interesting and promising area of research. The classification of the white blood cells plays an important part in the…

计算机视觉与模式识别 · 计算机科学 2021-12-14 Nalla Praveen , Narinder Singh Punn , Sanjay Kumar Sonbhadra , Sonali Agarwal , M. Syafrullah , Krisna Adiyarta

Convolutional neural network (CNN) has achieved unprecedented success in image super-resolution tasks in recent years. However, the network's performance depends on the distribution of the training sets and degrades on out-of-distribution…

计算机视觉与模式识别 · 计算机科学 2021-05-20 Aupendu Kar , Prabir Kumar Biswas

Melanoma is a sort of skin cancer that starts in the cells known as melanocytes. It is more dangerous than other types of skin cancer because it can spread to other organs. Melanoma can be fatal if it spreads to other parts of the body.…

图像与视频处理 · 电气工程与系统科学 2023-12-05 Md. Fahim Uddin , Nafisa Tafshir , Mohammad Monirujjaman Khan

Domain generalisation in computational histopathology is challenging because the images are substantially affected by differences among hospitals due to factors like fixation and staining of tissue and imaging equipment. We hypothesise that…

图像与视频处理 · 电气工程与系统科学 2024-11-15 Dhananjay Tomar , Alexander Binder , Andreas Kleppe

Nuclei segmentation is a fundamental task that is critical for various computational pathology applications including nuclei morphology analysis, cell type classification, and cancer grading. Conventional vision-based methods for nuclei…

计算机视觉与模式识别 · 计算机科学 2018-10-23 Faisal Mahmood , Daniel Borders , Richard Chen , Gregory N. McKay , Kevan J. Salimian , Alexander Baras , Nicholas J. Durr

Nowadays, deep learning methods, especially the convolutional neural networks (CNNs), have shown impressive performance on extracting abstract and high-level features from the hyperspectral image. However, general training process of CNNs…

计算机视觉与模式识别 · 计算机科学 2020-03-12 Zhiqiang Gong , Ping Zhong , Weidong Hu

The shape of erythrocytes or red blood cells is altered in several pathological conditions. Therefore, identifying and quantifying different erythrocyte shapes can help diagnose various diseases and assist in designing a treatment strategy.…

Melanoma, one of most dangerous types of skin cancer, re-sults in a very high mortality rate. Early detection and resection are two key points for a successful cure. Recent research has used artificial intelligence to classify melanoma and…

计算机视觉与模式识别 · 计算机科学 2020-08-31 Cong Tri Pham , Mai Chi Luong , Dung Van Hoang , Antoine Doucet

Cell detection and cell type classification from biomedical images play an important role for high-throughput imaging and various clinical application. While classification of single cell sample can be performed with standard computer…

图像与视频处理 · 电气工程与系统科学 2019-12-17 Wei Qiu , Jiaming Guo , Xiang Li , Mengjia Xu , Mo Zhang , Ning Guo , Quanzheng Li

Much progress has been made in the deep neural network (DNN) based diagnosis of mass lesions breast ultrasound (BUS) images. However, the non-mass lesion is less investigated because of the limited data. Based on the insight that mass data…

图像与视频处理 · 电气工程与系统科学 2022-04-20 Yangrun Hu , Yuanfan Guo , Fan Zhang , Mingda Wang , Tiancheng Lin , Rong Wu , Yi Xu

The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…

图像与视频处理 · 电气工程与系统科学 2024-07-19 Yuan Jin , Gege Ma , Geng Chen , Tianling Lyu , Jan Egger , Junhui Lyu , Shaoting Zhang , Wentao Zhu

Diffusion-weighted magnetic resonance imaging (DW-MRI) derived scalar maps are effective for assessing neurodegenerative diseases and microstructural properties of white matter in large number of brain conditions. However, DW-MRI inherently…

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

计算机视觉与模式识别 · 计算机科学 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

计算机视觉与模式识别 · 计算机科学 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Convolutional neural network (CNN) based segmentation methods provide an efficient and automated way for clinicians to assess the structure and function of the heart in cardiac MR images. While CNNs can generally perform the segmentation…

Skin cancer, the most common human malignancy, is primarily diagnosed visually by physicians [1]. Classification with an automated method like CNN [2, 3] shows potential for challenging tasks [1]. By now, the deep convolutional neural…

计算机视觉与模式识别 · 计算机科学 2017-03-13 Wenhao Zhang , Liangcai Gao , Runtao Liu