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Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Weakly supervised instance labeling using only image-level labels, in lieu of expensive fine-grained pixel annotations, is crucial in several applications including medical image analysis. In contrast to conventional instance segmentation…

计算机视觉与模式识别 · 计算机科学 2019-07-31 Jayaraman J. Thiagarajan , Satyananda Kashyap , Alexandros Karagyris

We describe a novel weakly supervised deep learning framework that combines both the discriminative and generative models to learn meaningful representation in the multiple instance learning (MIL) setting. MIL is a weakly supervised…

机器学习 · 计算机科学 2018-07-09 Shabnam Ghaffarzadegan

The burgeoning discipline of computational pathology shows promise in harnessing whole slide images (WSIs) to quantify morphological heterogeneity and develop objective prognostic modes for human cancers. However, progress is impeded by the…

计算机视觉与模式识别 · 计算机科学 2025-10-20 Chao Tu , Kun Huang , Jie Zhang , Qianjin Feng , Yu Zhang , Zhenyuan Ning

Machine learning models have become integral to many fields, but their reliability, defined as producing dependable, trustworthy, and domain-consistent predictions, remains a critical concern. Multiple Instance Learning (MIL) models…

计算机视觉与模式识别 · 计算机科学 2025-12-10 Hassan Keshvarikhojasteh , Marc Aubreville , Christof A. Bertram , Josien P. W. Pluim , Mitko Veta

Multiple-instance Learning (MIL) is commonly used to undertake computational pathology (CPath) tasks, and the use of multi-scale patches allows diverse features across scales to be learned. Previous studies using multi-scale features in…

计算机视觉与模式识别 · 计算机科学 2026-02-03 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A Fallowfield , Hakan Bilen , Timothy J Kendall

Computational pathology (CPath) digitizes pathology slides into whole slide images (WSIs), enabling analysis for critical healthcare tasks such as cancer diagnosis and prognosis. However, WSIs possess extremely long sequence lengths (up to…

计算机视觉与模式识别 · 计算机科学 2025-12-04 Wenhao Tang , Heng Fang , Ge Wu , Xiang Li , Ming-Ming Cheng

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

图像与视频处理 · 电气工程与系统科学 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

Offline imitation learning (IL) is a powerful method to solve decision-making problems from expert demonstrations without reward labels. Existing offline IL methods suffer from severe performance degeneration under limited expert data.…

机器学习 · 计算机科学 2023-01-11 Wenjia Zhang , Haoran Xu , Haoyi Niu , Peng Cheng , Ming Li , Heming Zhang , Guyue Zhou , Xianyuan Zhan

As a widely used weakly supervised learning scheme, modern multiple instance learning (MIL) models achieve competitive performance at the bag level. However, instance-level prediction, which is essential for many important applications,…

机器学习 · 计算机科学 2022-06-14 Hitesh Sapkota , Qi Yu

Weakly-supervised temporal action localization aims to localize and recognize actions in untrimmed videos with only video-level category labels during training. Without instance-level annotations, most existing methods follow the…

计算机视觉与模式识别 · 计算机科学 2023-05-30 Huan Ren , Wenfei Yang , Tianzhu Zhang , Yongdong Zhang

Traditional supervised learning tasks require a label for every instance in the training set, but in many real-world applications, labels are only available for collections (bags) of instances. This problem setting, known as multiple…

计算机视觉与模式识别 · 计算机科学 2023-05-23 Georg Wölflein , Lucie Charlotte Magister , Pietro Liò , David J. Harrison , Ognjen Arandjelović

The computer-aided analysis of medical scans is a longstanding goal in the medical imaging field. Currently, deep learning has became a dominant methodology for supporting pathologists and radiologist. Deep learning algorithms have been…

机器学习 · 计算机科学 2017-12-06 Jakub M. Tomczak , Maximilian Ilse , Max Welling

Class Incremental Learning (CIL) based on pre-trained models offers a promising direction for open-world continual learning. Existing methods typically rely on correlation-based strategies, where an image's classification feature is used as…

计算机视觉与模式识别 · 计算机科学 2025-05-20 Libo Huang , Zhulin An , Chuanguang Yang , Boyu Diao , Fei Wang , Yan Zeng , Zhifeng Hao , Yongjun Xu

In computational pathology, random sampling of patches during training of Multiple Instance Learning (MIL) methods is computationally efficient and serves as a regularization strategy. Despite its promising benefits, questions concerning…

计算机视觉与模式识别 · 计算机科学 2024-03-11 H. Keshvarikhojasteh , J. P. W. Pluim , M. Veta

Histopathology Whole Slide Image (WSI) analysis serves as the gold standard for clinical cancer diagnosis in the daily routines of doctors. To develop computer-aided diagnosis model for WSIs, previous methods typically employ Multi-Instance…

计算机视觉与模式识别 · 计算机科学 2024-10-21 Honglin Li , Yunlong Zhang , Pingyi Chen , Zhongyi Shui , Chenglu Zhu , Lin Yang

Strongly supervised learning requires detailed knowledge of truth labels at instance levels, and in many machine learning applications this is a major drawback. Multiple instance learning (MIL) is a popular weakly supervised learning method…

机器学习 · 计算机科学 2022-02-18 Saul Fuster , Trygve Eftestøl , Kjersti Engan

Whole Slide Images (WSIs) are typically analyzed using multiple instance learning (MIL) methods. However, the scale and heterogeneity of WSIs generate highly redundant and dispersed information, making it difficult to identify and integrate…

计算机视觉与模式识别 · 计算机科学 2025-12-23 Yueting Zhu , Yuehao Song , Shuai Zhang , Wenyu Liu , Xinggang Wang

Multiple Instance Learning (MIL) has been widely applied in histopathology to classify Whole Slide Images (WSIs) with slide-level diagnoses. While the ground truth is established by expert pathologists, the slides can be difficult to…

计算机视觉与模式识别 · 计算机科学 2026-03-11 Marie Arrivat , Rémy Peyret , Elsa Angelini , Pietro Gori

Multiple instance learning (MIL) aims to learn the mapping between a bag of instances and the bag-level label. In this paper, we propose a new end-to-end graph neural network (GNN) based algorithm for MIL: we treat each bag as a graph and…

机器学习 · 计算机科学 2019-06-13 Ming Tu , Jing Huang , Xiaodong He , Bowen Zhou
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