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Self-supervised learning has proven to be an effective way to learn representations in domains where annotated labels are scarce, such as medical imaging. A widely adopted framework for this purpose is contrastive learning and it has been…

计算机视觉与模式识别 · 计算机科学 2024-02-23 Hugo Figueiras , Helena Aidos , Nuno Cruz Garcia

We introduce a new benchmark dataset, Placenta, for node classification in an underexplored domain: predicting microanatomical tissue structures from cell graphs in placenta histology whole slide images. This problem is uniquely challenging…

Weakly-supervised classification of histopathology slides is a computationally intensive task, with a typical whole slide image (WSI) containing billions of pixels to process. We propose Discriminative Region Active Sampling for Multiple…

图像与视频处理 · 电气工程与系统科学 2023-02-23 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

Learning robust representations to discriminate cell phenotypes based on microscopy images is important for drug discovery. Drug development efforts typically analyse thousands of cell images to screen for potential treatments. Early works…

计算机视觉与模式识别 · 计算机科学 2021-12-28 Alexis Perakis , Ali Gorji , Samriddhi Jain , Krishna Chaitanya , Simone Rizza , Ender Konukoglu

Multimodal alignment of histopathology encoders with transcriptomic and genomic data has been shown to significantly improve performance in downstream diagnostic tasks. Hematological cytology is unique in that visual single-cell evaluation…

计算机视觉与模式识别 · 计算机科学 2026-05-29 Muhammed Furkan Dasdelen , Fatih Ozlugedik , Ilaria Looser , Rao Muhammad Umer , Christian Pohlkamp , Carsten Marr

Hispathological image segmentation algorithms play a critical role in computer aided diagnosis technology. The development of weakly supervised segmentation algorithm alleviates the problem of medical image annotation that it is…

计算机视觉与模式识别 · 计算机科学 2022-05-19 Ziniu Qian , Kailu Li , Maode Lai , Eric I-Chao Chang , Bingzheng Wei , Yubo Fan , Yan Xu

Gene expression can be used to subtype breast cancer with improved prediction of risk of recurrence and treatment responsiveness over that obtained using routine immunohistochemistry (IHC). However, in the clinic, molecular profiling is…

计算机视觉与模式识别 · 计算机科学 2023-05-09 Raktim Kumar Mondol , Ewan K. A. Millar , Peter H Graham , Lois Browne , Arcot Sowmya , Erik Meijering

We propose an exhaustive methodology that leverages all levels of feature abstraction, targeting an enhancement in the generalizability of image classification to unobserved hospitals. Our approach incorporates augmentation-based…

计算机视觉与模式识别 · 计算机科学 2023-08-10 Milad Sikaroudi , Maryam Hosseini , Shahryar Rahnamayan , H. R. Tizhoosh

Purpose - To characterise and assess the quality of published research evaluating artificial intelligence (AI) methods for ovarian cancer diagnosis or prognosis using histopathology data. Methods - A search of PubMed, Scopus, Web of…

图像与视频处理 · 电气工程与系统科学 2023-06-19 Jack Breen , Katie Allen , Kieran Zucker , Pratik Adusumilli , Andy Scarsbrook , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

We present a system for anomaly detection in histopathological images. In histology, normal samples are usually abundant, whereas anomalous (pathological) cases are scarce or not available. Under such settings, one-class classifiers trained…

计算机视觉与模式识别 · 计算机科学 2024-01-10 Igor Zingman , Birgit Stierstorfer , Charlotte Lempp , Fabian Heinemann

Accurate extraction of molecular representations is a critical step in the drug discovery process. In recent years, significant progress has been made in molecular representation learning methods, among which multi-modal molecular…

机器学习 · 计算机科学 2025-05-13 Rong Yin , Ruyue Liu , Xiaoshuai Hao , Xingrui Zhou , Yong Liu , Can Ma , Weiping Wang

Oncolytic viral therapy (OVT) is an emerging precision therapy for aggressive and recurrent cancers. However, its clinical efficacy is hindered by the complexity of tumor-virus-immune interactions and the lack of predictive models for…

定量方法 · 定量生物学 2026-03-11 Abicumaran Uthamacumaran , Juri Kiyokawa , Hiroaki Wakimoto

Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…

图像与视频处理 · 电气工程与系统科学 2023-06-28 Xiaofei Wang , Stephen Price , Chao Li

Recently, self-supervised learning has attracted attention due to its remarkable ability to acquire meaningful representations for classification tasks without using semantic labels. This paper introduces a self-supervised learning…

计算机视觉与模式识别 · 计算机科学 2022-02-09 Hyungtae Lee , Heesung Kwon

Renal Cell Carcinoma is typically asymptomatic at the early stages for many patients. This leads to a late diagnosis of the tumor, where the curability likelihood is lower, and makes the mortality rate of Renal Cell Carcinoma high, with…

计算机视觉与模式识别 · 计算机科学 2025-12-17 Mohamad Mohamad , Francesco Ponzio , Santa Di Cataldo , Damien Ambrosetti , Xavier Descombes

Ovarian cancer remains a challenging malignancy to diagnose and manage, with prognosis heavily dependent on the stage at detection. Accurate grading and staging, primarily based on histopathological examination of biopsy tissue samples, are…

医学物理 · 物理学 2025-05-16 Ashmit K Mishra , Mousa Alrubayan , Prabhakar Pradhan

Recent advances in computer vision and robotics enabled automated large-scale biological image analysis. Various machine learning approaches have been successfully applied to phenotypic profiling. However, it remains unclear how they…

图像与视频处理 · 电气工程与系统科学 2022-03-09 Andrei Dmitrenko , Mauro M. Masiero , Nicola Zamboni

Large pretrained transformers are increasingly being developed as generalised foundation models which can underpin powerful task-specific artificial intelligence models. Histopathology foundation models show great promise across many tasks,…

图像与视频处理 · 电气工程与系统科学 2024-09-10 Jack Breen , Katie Allen , Kieran Zucker , Lucy Godson , Nicolas M. Orsi , Nishant Ravikumar

Cervical cancer is a very common and fatal type of cancer in women. Cytopathology images are often used to screen for this cancer. Given that there is a possibility that many errors can occur during manual screening, a computer-aided…

计算机视觉与模式识别 · 计算机科学 2021-11-09 Wanli Liu , Chen Li , Md Mamunur Rahamana , Tao Jiang , Hongzan Sun , Xiangchen Wu , Weiming Hu , Haoyuan Chen , Changhao Sun , Yudong Yao , Marcin Grzegorzek

Melanoma is the most lethal form of skin cancer, with an increasing incidence rate worldwide. Analyzing histological images of melanoma by localizing and classifying tissues and cell nuclei is considered the gold standard method for…

计算机视觉与模式识别 · 计算机科学 2025-09-03 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod