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Biomechanical modeling of tissue deformation can be used to simulate different scenarios of longitudinal brain evolution. In this work,we present a deep learning framework for hyper-elastic strain modelling of brain atrophy, during healthy…

神经元与认知 · 定量生物学 2021-08-19 Mariana Da Silva , Carole H. Sudre , Kara Garcia , Cher Bass , M. Jorge Cardoso , Emma C. Robinson

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

定量方法 · 定量生物学 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo

Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

神经元与认知 · 定量生物学 2020-03-04 Taban Eslami , Joseph S. Raiker , Fahad Saeed

Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further…

Recent studies in neuroscience highlight the significant potential of brain connectivity networks, which are commonly constructed from functional magnetic resonance imaging (fMRI) data for brain disorder diagnosis. Traditional brain…

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

图像与视频处理 · 电气工程与系统科学 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Functional brain network analysis has become an indispensable tool for brain disease analysis. It is profoundly impacted by deep learning methods, which can characterize complex connections between ROIs. However, the research on foundation…

图像与视频处理 · 电气工程与系统科学 2025-08-08 Yifei Tang , Hongjie Jiang , Changhong Jing , Hieu Pham , Shuqiang Wang

Age is an important variable to describe the expected brain's anatomy status across the normal aging trajectory. The deviation from that normative aging trajectory may provide some insights into neurological diseases. In neuroimaging,…

计算机视觉与模式识别 · 计算机科学 2023-04-14 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Many studies have been conducted on machine learning techniques that…

机器学习 · 统计学 2019-04-15 Takashi Matsubara , Tetsuo Tashiro , Kuniaki Uehara

As the aging population grows, particularly for the baby boomer generation, the United States is witnessing a significant increase in the elderly population experiencing multifunctional disabilities. These disabilities, stemming from a…

机器学习 · 计算机科学 2024-04-09 Suiyao Chen , Xinyi Liu , Yulei Li , Jing Wu , Handong Yao

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

神经元与认知 · 定量生物学 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Recent success in training deep neural networks have prompted active investigation into the features learned on their intermediate layers. Such research is difficult because it requires making sense of non-linear computations performed by…

机器学习 · 计算机科学 2016-03-01 Yixuan Li , Jason Yosinski , Jeff Clune , Hod Lipson , John Hopcroft

Magnetic Resonance Imaging (MRI) is a principal diagnostic approach used in the field of radiology to create images of the anatomical and physiological structure of patients. MRI is the prevalent medical imaging practice to find…

计算机视觉与模式识别 · 计算机科学 2021-06-16 Yusuf Brima , Mossadek Hossain Kamal Tushar , Upama Kabir , Tariqul Islam

The field of neuroscience is facing an unprecedented expanse in the volume and diversity of available data. Traditionally, network models have provided key insights into the structure and function of the brain. With the advent of big data…

神经元与认知 · 定量生物学 2018-02-14 Michael Vaiana , Sarah Muldoon

Segmentation of focal (localized) brain pathologies such as brain tumors and brain lesions caused by multiple sclerosis and ischemic strokes are necessary for medical diagnosis, surgical planning and disease development as well as other…

计算机视觉与模式识别 · 计算机科学 2017-01-25 Mohammad Havaei , Nicolas Guizard , Hugo Larochelle , Pierre-Marc Jodoin

It has become increasingly popular to study the brain as a network due to the realization that functionality cannot be explained exclusively by independent activation of specialized regions. Instead, across a large spectrum of behaviors,…

神经元与认知 · 定量生物学 2014-07-22 Petko Bogdanov , Nazli Dereli , Danielle S. Bassett , Scott T. Grafton , Ambuj K. Singh

Despite the impressive advances achieved using deep learning for functional brain activity analysis, the heterogeneity of functional patterns and the scarcity of imaging data still pose challenges in tasks such as identifying neurological…

图像与视频处理 · 电气工程与系统科学 2025-05-30 Wenhui Cui , Haleh Akrami , Anand A. Joshi , Richard M. Leahy

Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…

神经元与认知 · 定量生物学 2022-07-26 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

Deep learning, a branch of artificial intelligence, is a data-driven method that uses multiple layers of interconnected units or neurons to learn intricate patterns and representations directly from raw input data. Empowered by this…

机器学习 · 计算机科学 2025-07-28 Mohd Halim Mohd Noor , Ayokunle Olalekan Ige

Although normal homologous brain structures are approximately symmetrical by definition, they also have shape differences due to e.g. natural ageing. On the other hand, neurodegenerative conditions induce their own changes in this…