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How can we build agents that keep learning from experience, quickly and efficiently, after their initial training? Here we take inspiration from the main mechanism of learning in biological brains: synaptic plasticity, carefully tuned by…

神经与进化计算 · 计算机科学 2018-08-01 Thomas Miconi , Jeff Clune , Kenneth O. Stanley

Sustainable research on computational models of neuronal networks requires published models to be understandable, reproducible, and extendable. Missing details or ambiguities about mathematical concepts and assumptions, algorithmic…

Neural plasticity is an important functionality of human brain, in which number of neurons and synapses can shrink or expand in response to stimuli throughout the span of life. We model this dynamic learning process as an $L_0$-norm…

神经与进化计算 · 计算机科学 2021-05-04 Yang Li , Shihao Ji

Convolutional networks are ubiquitous in deep learning. They are particularly useful for images, as they reduce the number of parameters, reduce training time, and increase accuracy. However, as a model of the brain they are seriously…

机器学习 · 计算机科学 2022-01-19 Roman Pogodin , Yash Mehta , Timothy P. Lillicrap , Peter E. Latham

Deep Convolutional Neural Networks (CNNs) achieve high accuracy but often rely on purely global, gradient-based optimisation, which can lead to overfitting, redundant filters, and reduced interpretability. To address these limitations, we…

机器学习 · 计算机科学 2025-08-28 Davorin Miličević , Ratko Grbić

To guide behavior, the brain extracts relevant features from high-dimensional data streamed by sensory organs. Neuroscience experiments demonstrate that the processing of sensory inputs by cortical neurons is modulated by instructive…

神经元与认知 · 定量生物学 2020-10-27 Siavash Golkar , David Lipshutz , Yanis Bahroun , Anirvan M. Sengupta , Dmitri B. Chklovskii

Neural network models of early sensory processing typically reduce the dimensionality of streaming input data. Such networks learn the principal subspace, in the sense of principal component analysis (PCA), by adjusting synaptic weights…

神经元与认知 · 定量生物学 2015-05-18 Cengiz Pehlevan , Tao Hu , Dmitri B. Chklovskii

Artificial neural networks (ANNs) are typically confined to accomplishing pre-defined tasks by learning a set of static parameters. In contrast, biological neural networks (BNNs) can adapt to various new tasks by continually updating the…

人工智能 · 计算机科学 2022-09-20 Fan Wang , Hao Tian , Haoyi Xiong , Hua Wu , Jie Fu , Yang Cao , Yu Kang , Haifeng Wang

Clinical neuroimaging has recently witnessed explosive growth in data availability which brings studying heterogeneity in clinical cohorts to the spotlight. Normative modeling is an emerging statistical tool for achieving this objective.…

Associative memory or content-addressable memory is an important component function in computer science and information processing, and at the same time a key concept in cognitive and computational brain science. Many different neural…

神经与进化计算 · 计算机科学 2026-05-05 Anders Lansner , Andreas Knoblauch , Naresh B Ravichandran , Pawel Herman

Understanding the operation of biological and artificial networks remains a difficult and important challenge. To identify general principles, researchers are increasingly interested in surveying large collections of networks that are…

机器学习 · 统计学 2022-01-14 Alex H. Williams , Erin Kunz , Simon Kornblith , Scott W. Linderman

Hebbian plasticity is a powerful principle that allows biological brains to learn from their lifetime experience. By contrast, artificial neural networks trained with backpropagation generally have fixed connection weights that do not…

神经与进化计算 · 计算机科学 2016-10-20 Thomas Miconi

Humans possess the capability to reason at an abstract level and to structure information into abstract categories, but the underlying neural processes have remained unknown. Experimental evidence has recently emerged for the organization…

神经元与认知 · 定量生物学 2022-04-05 Michael G. Müller , Christos H. Papadimitriou , Wolfgang Maass , Robert Legenstein

Artificial neural networks can be used to solve a variety of robotic tasks. However, they risk failing catastrophically when faced with out-of-distribution (OOD) situations. Several approaches have employed a type of synaptic plasticity…

Classic algorithms and machine learning systems like neural networks are both abundant in everyday life. While classic computer science algorithms are suitable for precise execution of exactly defined tasks such as finding the shortest path…

机器学习 · 计算机科学 2022-09-02 Felix Petersen

Artificial neural networks have diverged far from their early inspiration in neurology. In spite of their technological and commercial success, they have several shortcomings, most notably the need for a large number of training examples…

神经与进化计算 · 计算机科学 2019-12-04 J. Campbell Scott , Thomas F. Hayes , Ahmet S. Ozcan , Winfried W. Wilcke

Normative models of synaptic plasticity use a combination of mathematics and computational simulations to arrive at predictions of behavioral and network-level adaptive phenomena. In recent years, there has been an explosion of theoretical…

神经元与认知 · 定量生物学 2023-08-10 Colin Bredenberg , Cristina Savin

In machine learning, error back-propagation in multi-layer neural networks (deep learning) has been impressively successful in supervised and reinforcement learning tasks. As a model for learning in the brain, however, deep learning has…

机器学习 · 计算机科学 2016-12-19 Thomas Mesnard , Wulfram Gerstner , Johanni Brea

Learning and the ability to learn are important factors in development and evolutionary processes [1]. Depending on the level, the complexity of learning can strongly vary. While associative learning can explain simple learning behaviour…

神经元与认知 · 定量生物学 2007-05-23 Reimer Kuehn , Ion-Olimpiu Stamatescu

Modern scientific fields face the challenge of integrating a wealth of data, analyses, and results. We recently showed that a neglect of this integration can lead to circular analyses and redundant explanations. Here, we help advance…

神经元与认知 · 定量生物学 2025-08-15 Mika Rubinov