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The class distribution of data is one of the factors that regulates the performance of machine learning models. However, investigations on the impact of different distributions available in the literature are very few, sometimes absent for…
Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…
We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…
In histopathology, intelligent diagnosis of Whole Slide Images (WSIs) is essential for automating and objectifying diagnoses, reducing the workload of pathologists. However, diagnostic models often face the challenge of forgetting…
Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…
This paper introduces MAD-MIL, a Multi-head Attention-based Deep Multiple Instance Learning model, designed for weakly supervised Whole Slide Images (WSIs) classification in digital pathology. Inspired by the multi-head attention mechanism…
Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…
Whole slide image (WSI) classification is a critical task in computational pathology. However, the gigapixel-size of such images remains a major challenge for the current state of deep-learning. Current methods rely on multiple-instance…
Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…
Tumor segmentation stands as a pivotal task in cancer diagnosis. Given the immense dimensions of whole slide images (WSI) in histology, deep learning approaches for WSI classification mainly operate at patch-wise or superpixel-wise level.…
Whole slide image (WSI) has been widely used to assist automated diagnosis under the deep learning fields. However, most previous works only discuss the SINGLE task setting which is not aligned with real clinical setting, where pathologists…
Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to…
Digital pathology has attracted significant attention in recent years. Analysis of Whole Slide Images (WSIs) is challenging because they are very large, i.e., of Giga-pixel resolution. Identifying Regions of Interest (ROIs) is the first…
Cancer survival prediction is a challenging task that involves analyzing of the tumor microenvironment within Whole Slide Image (WSI). Previous methods cannot effectively capture the intricate interaction features among instances within the…
Early cancer detection is crucial for prognosis, but many cancer types lack large labelled datasets required for developing deep learning models. This paper investigates self-supervised learning (SSL) as an alternative to the standard…
Oncologists often rely on a multitude of data, including whole-slide images (WSIs), to guide therapeutic decisions, aiming for the best patient outcome. However, predicting the prognosis of cancer patients can be a challenging task due to…
Multiple instance learning (MIL) has emerged as a powerful framework for weakly supervised whole slide image (WSI) classification, enabling slide-level predictions without requiring detailed patch-level annotations. Despite its success, a…
Whole Slide Images (WSIs) play a crucial role in accurate cancer diagnosis and prognosis, as they provide tissue details at the cellular level. However, the rapid growth of computational tasks involving WSIs poses significant challenges.…
Digital pathology involves converting physical tissue slides into high-resolution Whole Slide Images (WSIs), which pathologists analyze for disease-affected tissues. However, large histology slides with numerous microscopic fields pose…
With the development of computer-aided diagnosis (CAD) and image scanning technology, Whole-slide Image (WSI) scanners are widely used in the field of pathological diagnosis. Therefore, WSI analysis has become the key to modern digital…